Docking, synthesis and antiproliferative activity of N-acylhydrazone derivatives designed as combretastatin A4 analogues
do Amaral, Daniel Nascimento, Cavalcanti, Bruno C, Bezerra, Daniel P, Ferreira, Paulo Michel P, Castro, Rosane de Paula, Sabino, José Ricardo, Machado, Camila Maria Longo, Chammas, Roger, Pessoa, Claudia, Sant'Anna, Carlos M R, Barreiro, Eliezer J, Lima, Lídia Moreira
Published in PloS one (10.03.2014)
Published in PloS one (10.03.2014)
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Design, Synthesis, and Pharmacological Evaluation of Novel N‑Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors
Rodrigues, Daniel A, Ferreira-Silva, Guilherme À, Ferreira, Ana C. S, Fernandes, Renan A, Kwee, Jolie K, Sant’Anna, Carlos M. R, Ionta, Marisa, Fraga, Carlos A. M
Published in Journal of medicinal chemistry (28.01.2016)
Published in Journal of medicinal chemistry (28.01.2016)
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Beneficial effects of a novel agonist of the adenosine A2A receptor on monocrotaline‐induced pulmonary hypertension in rats
Alencar, Allan K N, Pereira, Sharlene L, Montagnoli, Tadeu L, Maia, Rodolfo C, Kümmerle, Arthur E, Landgraf, Sharon S, Caruso‐Neves, Celso, Ferraz, Emanuelle B, Tesch, Roberta, Nascimento, José H M, Sant'Anna, Carlos M R, Fraga, Carlos A M, Barreiro, Eliezer J, Sudo, Roberto T, Zapata‐Sudo, Gisele
Published in British journal of pharmacology (01.07.2013)
Published in British journal of pharmacology (01.07.2013)
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Structure-property relationship studies of 3-acyl-substituted furans: the serendipitous identification and characterization of a new non-classical hydrogen bond donor moiety
Rodrigues, Daniel A, Pinheiro, Pedro de Sena M, Sagrillo, Fernanda, Freitas, Maria Clara, Alves, Marina, Thota, Sreekanth, Tinoco, Luzineide W, Magalhães, Alvicler, Sant'Anna, Carlos M. R, Fraga, Carlos A. M
Published in New journal of chemistry (14.07.2020)
Published in New journal of chemistry (14.07.2020)
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Evaluation by fluorescence, STD-NMR, docking and semi-empirical calculations of the o-NBA photo-acid interaction with BSA
Chaves, Otávio A., Jesus, Catarina S.H., Cruz, Pedro F., Sant'Anna, Carlos M.R., Brito, Rui M.M., Serpa, Carlos
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05.12.2016)
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05.12.2016)
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Quantitative Structure-Property Relationship (QSPR) Models for a Local Quantum Descriptor: Investigation of the 4- and 3-Substituted-Cinnamic Acid Esterification
Rodrigues-Santos, Cláudio E, Echevarria, Aurea, Sant'Anna, Carlos M R, Bitencourt, Thiago B, Nascimento, Maria G, Bauerfeldt, Glauco F
Published in Molecules (Basel, Switzerland) (22.09.2015)
Published in Molecules (Basel, Switzerland) (22.09.2015)
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NSAIDs revisited: Putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARγ)
Romeiro, Nelilma C., Sant'Anna, Carlos M.R., Lima, Lidia M., Fraga, Carlos A.M., Barreiro, Eliezer J.
Published in European journal of medicinal chemistry (01.09.2008)
Published in European journal of medicinal chemistry (01.09.2008)
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Design, Synthesis, and Pharmacological Evaluation of First‐in‐Class Multitarget N‐Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors
Rodrigues, Daniel A., Guerra, Fabiana S., Sagrillo, Fernanda S., Sena M. Pinheiro, Pedro, Alves, Marina A., Thota, Sreekanth, Chaves, Lorrane S., Sant'Anna, Carlos M. R., Fernandes, Patrícia D., Fraga, Carlos A. M.
Published in ChemMedChem (18.03.2020)
Published in ChemMedChem (18.03.2020)
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Molecular docking study and development of an empirical binding free energy model for phosphodiesterase 4 inhibitors
Oliveira, Fernanda G., Sant’Anna, Carlos M.R., Caffarena, Ernesto R., Dardenne, Laurent E., Barreiro, Eliezer J.
Published in Bioorganic & medicinal chemistry (01.09.2006)
Published in Bioorganic & medicinal chemistry (01.09.2006)
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N -acylhydrazone derivative ameliorates monocrotaline-induced pulmonary hypertension through the modulation of adenosine AA2R activity
Alencar, Allan K.N, Pereira, Sharlene L, da Silva, Flavia E, Mendes, Luiza V.P, Cunha, Valéria do M.N, Lima, Lidia M, Montagnoli, Tadeu L, Caruso-Neves, Celso, Ferraz, Emanuelle B, Tesch, Roberta, Nascimento, José H.M, Sant'Anna, Carlos M.R, Fraga, Carlos A.M, Barreiro, Eliezer J, Sudo, Roberto T, Zapata-Sudo, Gisele
Published in International journal of cardiology (01.05.2014)
Published in International journal of cardiology (01.05.2014)
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Antihypertensive profile of 2-thienyl-3,4-methylenedioxybenzoylhydrazone is mediated by activation of the A2A adenosine receptor
Leal, Carla Moreira, Pereira, Sharlene Lopes, Kümmerle, Arthur Eugen, Leal, Daniella Moreira, Tesch, Roberta, de Sant’Anna, Carlos M.R., Fraga, Carlos Alberto M., Barreiro, Eliezer Jesus, Sudo, Roberto Takashi, Zapata-Sudo, Gisele
Published in European journal of medicinal chemistry (01.09.2012)
Published in European journal of medicinal chemistry (01.09.2012)
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Structural insights into cholinesterases inhibition by harmane β-carbolinium derivatives: A kinetics – molecular modeling approach
Torres, Juliana M., Lira, Aline F., Silva, Daniel R., Guzzo, Lucas M., Sant’Anna, Carlos M.R., Kümmerle, Arthur E., Rumjanek, Victor M.
Published in Phytochemistry (Oxford) (01.09.2012)
Published in Phytochemistry (Oxford) (01.09.2012)
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Structure-based design and biological profile of ( E)- N-(4-Nitrobenzylidene)-2-naphthohydrazide, a novel small molecule inhibitor of IκB kinase-β
Avila, Carolina M., Lopes, Alexandra B., Gonçalves, Arlan S., da Silva, Leandro L., Romeiro, Nelilma C., Miranda, Ana Luisa P., Sant’Anna, Carlos M.R., Barreiro, Eliezer J., Fraga, Carlos A.M.
Published in European journal of medicinal chemistry (01.04.2011)
Published in European journal of medicinal chemistry (01.04.2011)
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LASSBio-897 Reduces Lung Injury Induced by Silica Particles in Mice: Potential Interaction with the A2A Receptor
Carvalho, Vinicius F., Ferreira, Tatiana P. T., de Arantes, Ana C. S., Noël, François, Tesch, Roberta, Sant’Anna, Carlos M. R., Barreiro, Eliezer J. L., Fraga, Carlos A. M., Rodrigues e Silva, Patrícia M., Martins, Marco A.
Published in Frontiers in pharmacology (31.10.2017)
Published in Frontiers in pharmacology (31.10.2017)
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A novel 3D-QSAR comparative molecular field analysis (CoMFA) model of imidazole and quinazolinone functionalized p38 MAP kinase inhibitors
Sperandio da Silva, Gilberto M., Sant'Anna, Carlos M.R., Barreiro, Eliezer J.
Published in Bioorganic & medicinal chemistry (15.06.2004)
Published in Bioorganic & medicinal chemistry (15.06.2004)
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New triterpene glycoside and other chemical constituents from the leaves of Swartzia apetala Raddi var. glabra
de Araújo, Marcelo F., Curcino Vieira, Ivo J., Sant'Anna, Carlos M.R., da Silva, Daniel Rosa, Vitorino Maia, Ana Isabel, Braz-Filho, Raimundo, Vieira-da-Motta, Olney, Mathias, Leda
Published in Natural product research (01.10.2013)
Published in Natural product research (01.10.2013)
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