Cell Lineage Tracing Identifies Hormone-Regulated and Wnt-Responsive Vaginal Epithelial Stem Cells
Ali, Ayesha, Syed, Shafiq M., Jamaluddin, M. Fairuz B., Colino-Sanguino, Yolanda, Gallego-Ortega, David, Tanwar, Pradeep S.
Published in Cell reports (Cambridge) (04.02.2020)
Published in Cell reports (Cambridge) (04.02.2020)
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DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns
Skvortsova, Ksenia, Masle-Farquhar, Etienne, Luu, Phuc-Loi, Song, Jenny Z., Qu, Wenjia, Zotenko, Elena, Gould, Cathryn M., Du, Qian, Peters, Timothy J., Colino-Sanguino, Yolanda, Pidsley, Ruth, Nair, Shalima S., Khoury, Amanda, Smith, Grady C., Miosge, Lisa A., Reed, Joanne H., Kench, James G., Rubin, Mark A., Horvath, Lisa, Bogdanovic, Ozren, Lim, Sue Mei, Polo, Jose M., Goodnow, Christopher C., Stirzaker, Clare, Clark, Susan J.
Published in Cancer cell (11.02.2019)
Published in Cancer cell (11.02.2019)
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Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer
Valdés-Mora, Fátima, Gould, Cathryn M, Colino-Sanguino, Yolanda, Qu, Wenjia, Song, Jenny Z, Taylor, Kylie M, Buske, Fabian A, Statham, Aaron L, Nair, Shalima S, Armstrong, Nicola J, Kench, James G, Lee, Kenneth M L, Horvath, Lisa G, Qiu, Minru, Ilinykh, Alexei, Yeo-Teh, Nicole S, Gallego-Ortega, David, Stirzaker, Clare, Clark, Susan J
Published in Nature communications (07.11.2017)
Published in Nature communications (07.11.2017)
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Performance comparison of high throughput single-cell RNA-Seq platforms in complex tissues
Colino-Sanguino, Yolanda, Rodriguez de la Fuente, Laura, Gloss, Brian, Law, Andrew M.K., Handler, Kristina, Pajic, Marina, Salomon, Robert, Gallego-Ortega, David, Valdes-Mora, Fatima
Published in Heliyon (01.09.2024)
Published in Heliyon (01.09.2024)
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Clinical relevance of the transcriptional signature regulated by CDC42 in colorectal cancer
Valdés-Mora, Fatima, Locke, Warwick J, Bandrés, Eva, Gallego-Ortega, David, Cejas, Paloma, García-Cabezas, Miguel Angel, Colino-Sanguino, Yolanda, Feliú, Jaime, Del Pulgar, Teresa Gómez, Lacal, Juan Carlos
Published in Oncotarget (18.04.2017)
Published in Oncotarget (18.04.2017)
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Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson's disease
Tamburrino, Anna, Churchill, Madeline J, Wan, Oi W, Colino-Sanguino, Yolanda, Ippolito, Rossana, Bergstrand, Sofie, Wolf, Daniel A, Herz, Niculin J, Sconce, Michelle D, Björklund, Anders, Meshul, Charles K, Decressac, Mickael
Published in Acta neuropathologica communications (14.12.2015)
Published in Acta neuropathologica communications (14.12.2015)
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A Read/Write Mechanism Connects p300 Bromodomain Function to H2A.Z Acetylation
Colino-Sanguino, Yolanda, Cornett, Evan M., Moulder, David, Smith, Grady C., Hrit, Joel, Cordeiro-Spinetti, Eric, Vaughan, Robert M., Krajewski, Krzysztof, Rothbart, Scott B., Clark, Susan J., Valdés-Mora, Fátima
Published in iScience (22.11.2019)
Published in iScience (22.11.2019)
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ALTEN: A High‐Fidelity Primary Tissue‐Engineering Platform to Assess Cellular Responses Ex Vivo
Law, Andrew M. K., Chen, Jiamin, Colino‐Sanguino, Yolanda, Fuente, Laura Rodriguez de la, Fang, Guocheng, Grimes, Susan M., Lu, Hongxu, Huang, Robert J., Boyle, Sarah T., Venhuizen, Jeron, Castillo, Lesley, Tavakoli, Javad, Skhinas, Joanna N., Millar, Ewan K. A., Beretov, Julia, Rossello, Fernando J., Tipper, Joanne L., Ormandy, Christopher J., Samuel, Michael S., Cox, Thomas R., Martelotto, Luciano, Jin, Dayong, Valdes‐Mora, Fatima, Ji, Hanlee P., Gallego‐Ortega, David
Published in Advanced science (01.07.2022)
Published in Advanced science (01.07.2022)
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The H2A.Z-nuclesome code in mammals: emerging functions
Colino-Sanguino, Yolanda, Clark, Susan J, Valdes-Mora, Fatima
Published in Trends in genetics (01.03.2022)
Published in Trends in genetics (01.03.2022)
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The H2A.Z-nucleosome code in mammals: emerging functions
Colino-Sanguino, Yolanda, Clark, Susan J., Valdes-Mora, Fatima
Published in Trends in genetics (01.03.2022)
Published in Trends in genetics (01.03.2022)
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The H2A.Z-nucleosome code in mammals: emerging functions
Colino-Sanguino, Yolanda, Clark, Susan J., Valdes-Mora, Fatima
Published in Trends in genetics (01.05.2022)
Published in Trends in genetics (01.05.2022)
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DIPG-24. COMBINED EPIGENETIC THERAPY WITH FACT AND BET INHIBITORS REMODELS CHROMATIN AND DISRUPTS ONCOGENIC TRANSCRIPTION IN DIFFUSE MIDLINE GLIOMA
Holliday, Holly, Khan, Aaminah, Jayatilleke, Nisitha, Mayoh, Chelsea, Ross, Samuel E, Guo, Xinyi, Sanguino, Yolanda Colino, Gopalakrishnan, Anjana, Ehteda, Anahid, Tsoli, Maria, Ziegler, David S
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma
Jackson, Evangeline R, Duchatel, Ryan J, Staudt, Dilana E, Persson, Mika L, Mannan, Abdul, Yadavilli, Sridevi, Parackal, Sarah, Game, Shaye, Chong, Wai Chin, Jayasekara, W Samantha Nilanthi, Le Grand, Marion, Kearney, Padraic S, Douglas, Alicia M, Findlay, Izac J, Germon, Zacary P, McEwen, Holly P, Beitaki, Tyrone S, Patabendige, Adjanie, Skerrett-Byrne, David A, Nixon, Brett, Smith, Nathan D, Day, Bryan, Manoharan, Neevika, Nagabushan, Sumanth, Hansford, Jordan R, Govender, Dinisha, McCowage, Geoffrey B, Firestein, Ron, Howlett, Meegan, Endersby, Raelene, Gottardo, Nicholas G, Alvaro, Frank, Waszak, Sebastian M, Larsen, Martin R, Colino-Sanguino, Yolanda, Valdés-Mora, Fatima, Rakotomalala, Andria, Meignan, Samuel, Pasquier, Eddy, Andre, Nicolas, Hulleman, Esther, Eisenstat, David D, Vitanza, Nicholas A, Nazarian, Javad, Koschmann, Carl, Mueller, Sabine, Cain, Jason E, Dun, Matthew D
Published in Cancer research (Chicago, Ill.) (05.05.2023)
Published in Cancer research (Chicago, Ill.) (05.05.2023)
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DIPG-37. Exploring the role of the epigenetic factor H2A.Z acetylation in DIPG
Sanguino, Yolanda Colino, de la Fuente, Laura Rodriguez, Kisswani, Dana, Kearney, Padraic, Jackson, Evangeline, Duchatel, Ryan, Holliday, Holly, Jabado, Nada, Tsoli, Maria, Ziegler, David, Dun, Matthew, Mora, Fatima Valdes
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
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Journal Article
PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
Duchatel, Ryan J, Jackson, Evangeline R, Parackal, Sarah G, Kiltschewskij, Dylan, Findlay, Izac J, Mannan, Abdul, Staudt, Dilana E, Thomas, Bryce C, Germon, Zacary P, Laternser, Sandra, Kearney, Padraic S, Jamaluddin, M Fairuz B, Douglas, Alicia M, Beitaki, Tyrone, McEwen, Holly P, Persson, Mika L, Hocke, Emily A, Jain, Vaibhav, Aksu, Michael, Manning, Elizabeth E, Murray, Heather C, Verrills, Nicole M, Sun, Claire Xin, Daniel, Paul, Vilain, Ricardo E, Skerrett-Byrne, David A, Nixon, Brett, Hua, Susan, de Bock, Charles E, Colino-Sanguino, Yolanda, Valdes-Mora, Fatima, Tsoli, Maria, Ziegler, David S, Cairns, Murray J, Raabe, Eric H, Vitanza, Nicholas A, Hulleman, Esther, Phoenix, Timothy N, Koschmann, Carl, Alvaro, Frank, Dayas, Christopher V, Tinkle, Christopher L, Wheeler, Helen, Whittle, James R, Eisenstat, David D, Firestein, Ron, Mueller, Sabine, Valvi, Santosh, Hansford, Jordan R, Ashley, David M, Gregory, Simon G, Kilburn, Lindsay B, Nazarian, Javad, Cain, Jason E, Dun, Matthew D
Published in The Journal of clinical investigation (15.03.2024)
Published in The Journal of clinical investigation (15.03.2024)
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EXTH-36. COMBINING ONC201 AND PAXALISIB FOR THE TREATMENT OF DIFFUSE MIDLINE GLIOMA (DMG); THE PRECLINICAL RESULTS UNDERPINNING THE INTERNATIONAL PHASE II CLINICAL TRIAL (NCT05009992)
Jackson, Evangeline, Duchatel, Ryan, Staudt, Dilana, Persson, Mika, Mannan, Abdul, Yadavilli, Sridevi, Parackal, Sarah, Game, Shaye, Chong, Wai Chin, Jayasekara, W Samantha, Grand, Marion Le, Kearney, Padraic, Douglas, Alicia, Findlay, Izac, Germon, Zacary, McEwen, Holly, Beitaki, Tyrone, Patabendige, Adjanie, Skerrett-byrne, David, Nixon, Brett, Smith, Nathan, Day, Bryan, Manoharan, Neevika, Nagabushan, Sumanth, Hansford, Jordan, Govender, Dinisher, McCowage, Geoffrey, Firestein, Ron, Howlett, Meegan, Endersby, Raelene, Gottardo, Nicholas, Alvaro, Frank, Waszak, Sebastian, Larsen, Martin, Sanguino, Yolanda Colino, Valdes-Mora, Fatima, Rakotomalala, Andria, Meignan, Samuel, Pasquier, Eddy, Andre, Nicolas, Hulleman, Esther, Eisenstat, David, Vitanza, Nicholas, Nazarian, Javad, Koschmann, Carl, Mueller, Sabine, Cain, Jason, Dun, Matthew
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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Abstract B016: Targeting the epigenome through combined Facilitates Chromatin Transcription (FACT) and Bromodomain and Extra-Terminal Domain (BET) inhibition in Diffuse Midline Glioma (DMG)
Holliday, Holly, Khan, Aaminah, Jayatilleke, Nisitha, Mayoh, Chelsea, Ross, Samuel E., Sanguino, Yolanda Colino, Gopalakrishnan, Anjana, Ehteda, Anahid, Rayner, Benjamin, Tsoli, Maria, Ziegler, David S.
Published in Cancer research (Chicago, Ill.) (04.03.2024)
Published in Cancer research (Chicago, Ill.) (04.03.2024)
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EXTH-12. PRECLINICAL AND CASE STUDY EXAMINATION OF THE COMBINATION OF THE CLPP AGONIST ONC201 WITH THE PI3K/AKT INHIBITOR PAXALISIB FOR THE TREATMENT OF DIFFUSE MIDLINE GLIOMA
Jackson, Evangeline, Duchatel, Ryan, Persson, Mika, Mannan, Abdul, Yadavilli, Sridevi, Parackal, Sarah, Game, Shaye, Chong, Wai Chin, Jayasekara, Samantha, Le Grand, Marion, Kearney, Padraic, Douglas, Alicia, Findlay, Izac, Staudt, Dilana, Germon, Zacary, Skerrett-Byrne, David, Nixon, Brett, Smith, Nathan, Hulleman, Esther, Day, Bryan, McCowage, Geoffrey, Alvaro, Frank, Waszak, Sebastian, Larsen, Martin, Colino-Sanguino, Yolanda, Valdes-Mora, Fatima, Rakotomalala, Andria, Meignan, Samuel, Pasquier, Eddy, Vitanza, Nicholas, Nazarian, Javad, Koschmann, Carl, Cain, Jason, Mueller, Sabine, Dun, Matthew
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
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DIPG-07. Preclinical and case study results underpinning the phase II clinical trial testing the combination of ONC201 and paxalisib for the treatment of patients with diffuse midline glioma (NCT05009992)
Dun, Matthew D, Jackson, Evangeline R, Duchatel, Ryan J, Persson, Mika L, Mannan, Abdul, Yadavilli, Sridevi, Parackal, Sarah, Game, Shaye, Chong, Wai Chin, Jayasekara, Samantha, Le Grand, Marion, Kearney, Padraic S, Douglas, Alicia M, Findlay, Izac J, Staudt, Dilana, Germon, Zacary P, Skerrett-Byrne, David A, Nixon, Brett, Smith, Nathan D, Hulleman, Esther, Day, Bryan, McCowage, Geoff B, Alvaro, Frank, Waszak, Sebastian M, Larsen, Martin R, Colino-Sanguino, Yolanda, Valdes-Mora, Fatima, Rakotomalala, Andria, Meignan, Samuel, Pasquier, Eddy, Vitanza, Nicholas A, Nazarian, Javad, Koschmann, Carl, Cain, Jason, Mueller, Sabine
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
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