Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
Prinz, Marco, Ransohoff, Richard M, Priller, Josef, Sisodia, Sangram S
Published in Nature neuroscience (01.10.2011)
Published in Nature neuroscience (01.10.2011)
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Journal Article
The gut microbiome in Alzheimer's disease: what we know and what remains to be explored
Chandra, Sidhanth, Sisodia, Sangram S, Vassar, Robert J
Published in Molecular neurodegeneration (01.02.2023)
Published in Molecular neurodegeneration (01.02.2023)
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Journal Article
Sex-specific effects of microbiome perturbations on cerebral Aβ amyloidosis and microglia phenotypes
Dodiya, Hemraj B, Kuntz, Thomas, Shaik, Shabana M, Baufeld, Caroline, Leibowitz, Jeffrey, Zhang, Xulun, Gottel, Neil, Zhang, Xiaoqiong, Butovsky, Oleg, Gilbert, Jack A, Sisodia, Sangram S
Published in The Journal of experimental medicine (01.07.2019)
Published in The Journal of experimental medicine (01.07.2019)
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Journal Article
Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer’s disease
Minter, Myles R., Zhang, Can, Leone, Vanessa, Ringus, Daina L., Zhang, Xiaoqiong, Oyler-Castrillo, Paul, Musch, Mark W., Liao, Fan, Ward, Joseph F., Holtzman, David M., Chang, Eugene B., Tanzi, Rudolph E., Sisodia, Sangram S.
Published in Scientific reports (21.07.2016)
Published in Scientific reports (21.07.2016)
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Journal Article
Synergistic depletion of gut microbial consortia, but not individual antibiotics, reduces amyloidosis in APPPS1-21 Alzheimer’s transgenic mice
Dodiya, Hemraj B., Frith, Mary, Sidebottom, Ashley, Cao, Yajun, Koval, Jason, Chang, Eugene, Sisodia, Sangram S.
Published in Scientific reports (18.05.2020)
Published in Scientific reports (18.05.2020)
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Journal Article
ApoE isoform- and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy
Seo, Dong-Oh, O'Donnell, David, Jain, Nimansha, Ulrich, Jason D, Herz, Jasmin, Li, Yuhao, Lemieux, Mackenzie, Cheng, Jiye, Hu, Hao, Serrano, Javier R, Bao, Xin, Franke, Emily, Karlsson, Maria, Meier, Martin, Deng, Su, Desai, Chandani, Dodiya, Hemraj, Lelwala-Guruge, Janaki, Handley, Scott A, Kipnis, Jonathan, Sisodia, Sangram S, Gordon, Jeffrey I, Holtzman, David M
Published in Science (American Association for the Advancement of Science) (13.01.2023)
Published in Science (American Association for the Advancement of Science) (13.01.2023)
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Journal Article
Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging
Füger, Petra, Hefendehl, Jasmin K, Veeraraghavalu, Karthik, Wendeln, Ann-Christin, Schlosser, Christine, Obermüller, Ulrike, Wegenast-Braun, Bettina M, Neher, Jonas J, Martus, Peter, Kohsaka, Shinichi, Thunemann, Martin, Feil, Robert, Sisodia, Sangram S, Skodras, Angelos, Jucker, Mathias
Published in Nature neuroscience (01.10.2017)
Published in Nature neuroscience (01.10.2017)
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Journal Article
Deficits in Enrichment-Dependent Neurogenesis and Enhanced Anxiety Behaviors Mediated by Expression of Alzheimer's Disease-Linked Ps1 Variants Are Rescued by Microglial Depletion
Ortega-Martinez, Sylvia, Palla, Nisha, Zhang, Xiaoqiong, Lipman, Erin, Sisodia, Sangram S
Published in The Journal of neuroscience (21.08.2019)
Published in The Journal of neuroscience (21.08.2019)
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Journal Article
Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer’s disease
Minter, Myles R., Hinterleitner, Reinhard, Meisel, Marlies, Zhang, Can, Leone, Vanessa, Zhang, Xiaoqiong, Oyler-Castrillo, Paul, Zhang, Xulun, Musch, Mark W., Shen, Xunuo, Jabri, Bana, Chang, Eugene B., Tanzi, Rudolph E., Sisodia, Sangram S.
Published in Scientific reports (05.09.2017)
Published in Scientific reports (05.09.2017)
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Journal Article
Gut microbiota-driven brain Aβ amyloidosis in mice requires microglia
Dodiya, Hemraj B, Lutz, Holly L, Weigle, Ian Q, Patel, Priyam, Michalkiewicz, Julia, Roman-Santiago, Carlos J, Zhang, Can Martin, Liang, Yingxia, Srinath, Abhinav, Zhang, Xulun, Xia, Jessica, Olszewski, Monica, Zhang, Xiaoqiong, Schipma, Matthew John, Chang, Eugene B, Tanzi, Rudolph E, Gilbert, Jack A, Sisodia, Sangram S
Published in The Journal of experimental medicine (03.01.2022)
Published in The Journal of experimental medicine (03.01.2022)
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Journal Article
A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2
Zhang, Xulun, Garbett, Krassimira, Veeraraghavalu, Karthikeyan, Wilburn, Brian, Gilmore, Reid, Mirnics, Karoly, Sisodia, Sangram S
Published in The Journal of neuroscience (20.06.2012)
Published in The Journal of neuroscience (20.06.2012)
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Journal Article
Increased Type I interferon signaling and brain endothelial barrier dysfunction in an experimental model of Alzheimer’s disease
Jana, Arundhati, Wang, Xinge, Leasure, Joseph W., Magana, Lissette, Wang, Li, Kim, Young-Mee, Dodiya, Hemraj, Toth, Peter T., Sisodia, Sangram S., Rehman, Jalees
Published in Scientific reports (01.10.2022)
Published in Scientific reports (01.10.2022)
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Journal Article
DNA-based fluorescent probes of NOS2 activity in live brains
Veetil, Aneesh T., Zou, Junyi, Henderson, Katharine W., Jani, Maulik S., Shaik, Shabana M., Sisodia, Sangram S., Hale, Melina E., Krishnan, Yamuna
Published in Proceedings of the National Academy of Sciences - PNAS (30.06.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (30.06.2020)
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Journal Article
Amyloid beta from axons and dendrites reduces local spine number and plasticity
Wei, Wei, Malinow, Roberto, Nguyen, Louis N, Sisodia, Sangram, Hagiwara, Hiroaki, Kessels, Helmut W
Published in Nature neuroscience (01.02.2010)
Published in Nature neuroscience (01.02.2010)
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Journal Article
Nontranscriptional Role of Hif-1α in Activation of γ-Secretase and Notch Signaling in Breast Cancer
Villa, Jennifer C., Chiu, Danica, Brandes, Alissa H., Escorcia, Freddy E., Villa, Carlos H., Maguire, William F., Hu, Cheng-Jun, de Stanchina, Elisa, Simon, M. Celeste, Sisodia, Sangram S., Scheinberg, David A., Li, Yue-Ming
Published in Cell reports (Cambridge) (21.08.2014)
Published in Cell reports (Cambridge) (21.08.2014)
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