Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm
Wong, Philip C, Zheng, Hui, Chen, Hua, Becher, Mark W, Sirinathsinghji, Dalip J. S, Trumbauer, Myrna E, Chen, Howard Y, Price, Donald L, Van der Ploeg, Lex H. T, Sisodia, Sangram S
Published in Nature (London) (01.05.1997)
Published in Nature (London) (01.05.1997)
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Journal Article
Presenilin-dependent “γ-Secretase” Processing of Deleted in Colorectal Cancer (DCC)
Taniguchi, Yoshihito, Kim, Seong-Hun, Sisodia, Sangram S.
Published in The Journal of biological chemistry (15.08.2003)
Published in The Journal of biological chemistry (15.08.2003)
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Journal Article
ALZHEIMER'S DISEASE: Genetic Studies and Transgenic Models
Price, Donald L, Tanzi, Rudolph E, Borchelt, David R, Sisodia, Sangram S
Published in Annual review of genetics (01.01.1998)
Published in Annual review of genetics (01.01.1998)
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Journal Article
Effects of PS1 deficiency on membrane protein trafficking in neurons
Naruse, S, Thinakaran, G, Luo, J J, Kusiak, J W, Tomita, T, Iwatsubo, T, Qian, X, Ginty, D D, Price, D L, Borchelt, D R, Wong, P C, Sisodia, S S
Published in Neuron (Cambridge, Mass.) (01.11.1998)
Published in Neuron (Cambridge, Mass.) (01.11.1998)
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Journal Article
Evidence That CD147 Modulation of β-Amyloid (Aβ) Levels Is Mediated by Extracellular Degradation of Secreted Aβ
Vetrivel, Kulandaivelu S., Zhang, Xulun, Meckler, Xavier, Cheng, Haipeng, Lee, Sungho, Gong, Ping, Lopes, Kryslaine O., Chen, Ying, Iwata, Nobuhisa, Yin, Ke-Jie, Lee, Jin-Moo, Parent, Angèle T., Saido, Takaomi C., Li, Yue-Ming, Sisodia, Sangram S., Thinakaran, Gopal
Published in The Journal of biological chemistry (11.07.2008)
Published in The Journal of biological chemistry (11.07.2008)
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Journal Article
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
Wong, Philip C, Pardo, Carlos A, Borchelt, David R, Lee, Michael K, Copeland, Neal G, Jenkins, Nancy A, Sisodia, Sangram S, Cleveland, Don W, Price, Donald L
Published in Neuron (Cambridge, Mass.) (01.06.1995)
Published in Neuron (Cambridge, Mass.) (01.06.1995)
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Journal Article
Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo
Thinakaran, Gopal, Borchelt, David R, Lee, Michael K, Slunt, Hilda H, Spitzer, Lia, Kim, Grace, Ratovitsky, Tamara, Davenport, Frances, Nordstedt, Christer, Seeger, Mary, Hardy, John, Levey, Allan I, Gandy, Samuel E, Jenkins, Nancy A, Copeland, Neal G, Price, Donald L, Sisodia, Sangram S
Published in Neuron (Cambridge, Mass.) (01.07.1996)
Published in Neuron (Cambridge, Mass.) (01.07.1996)
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Journal Article
Enhanced Accumulation of Phosphorylated α-Synuclein and Elevated β-Amyloid 42/40 Ratio Caused by Expression of the Presenilin-1 ΔT440 Mutant Associated with Familial Lewy Body Disease and Variant Alzheimer's Disease
Kaneko, Hiroyuki, Kakita, Akiyoshi, Kasuga, Kensaku, Nozaki, Hiroaki, Ishikawa, Atsushi, Miyashita, Akinori, Kuwano, Ryozo, Ito, Genta, Iwatsubo, Takeshi, Takahashi, Hitoshi, Nishizawa, Masatoyo, Onodera, Osamu, Sisodia, Sangram S., Ikeuchi, Takeshi
Published in The Journal of neuroscience (28.11.2007)
Published in The Journal of neuroscience (28.11.2007)
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Journal Article
Presenilin Attenuates Receptor-Mediated Signaling and Synaptic Function
Parent, Angele T, Barnes, Natalie Y, Taniguchi, Yoshihito, Thinakaran, Gopal, Sisodia, Sangram S
Published in The Journal of neuroscience (09.02.2005)
Published in The Journal of neuroscience (09.02.2005)
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Journal Article
Nigrostriatal Dysfunction in Familial Alzheimer's Disease-Linked APPswe/PS1ΔE9 Transgenic Mice
Perez, Sylvia E., Lazarov, Orly, Koprich, James B., Chen, Er-Yun, Rodriguez-Menendez, Virginia, Lipton, Jack W., Sisodia, Sangram S., Mufson, Elliott J.
Published in The Journal of neuroscience (02.11.2005)
Published in The Journal of neuroscience (02.11.2005)
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Journal Article
Alzheimer Amyloid Protein Precursor in the Rat Hippocampus: Transport and Processing through the Perforant Path
Buxbaum, Joseph D, Thinakaran, Gopal, Koliatsos, Vassilis, O'Callahan, James, Slunt, Hilda H, Price, Donald L, Sisodia, Sangram S
Published in The Journal of neuroscience (01.12.1998)
Published in The Journal of neuroscience (01.12.1998)
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Journal Article
Assessment of Normal and Mutant Human Presenilin Function in Caenorhabditis elegans
Levitan, Diane, Doyle, Timothy G., Brousseau, Denise, Lee, Michael K., Thinakaran, Gopal, Slunt, Hilda H., Sisodia, Sangram S., Greenwald, Iva
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.1996)
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Journal Article
Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein
Cai, Dongming, Leem, Jae Yoon, Greenfield, Jeffrey P, Wang, Pei, Kim, Benny S, Wang, Runsheng, Lopes, Kryslaine O, Kim, Seong-Hun, Zheng, Hui, Greengard, Paul, Sisodia, Sangram S, Thinakaran, Gopal, Xu, Huaxi
Published in The Journal of biological chemistry (31.01.2003)
Published in The Journal of biological chemistry (31.01.2003)
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Journal Article
A mouse model for Down syndrome exhibits learning and behaviour deficits
Reeves, Roger H, Irving, Nicholas G, Moran, Timothy H, Wohn, Anny, Kitt, Cheryl, Sisodia, Sangram S, Schmidt, Cecilia, Bronson, Roderick T, Davisson, Muriel T
Published in Nature genetics (01.10.1995)
Published in Nature genetics (01.10.1995)
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Journal Article
Presenilin 1 in migration and morphogenesis in the central nervous system
Louvi, Angeliki, Sisodia, Sangram S, Grove, Elizabeth A
Published in Development (Cambridge) (01.07.2004)
Published in Development (Cambridge) (01.07.2004)
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Journal Article
APP Transgenic Mice Tg2576 Accumulate Aβ Peptides That Are Distinct from the Chemically Modified and Insoluble Peptides Deposited in Alzheimer's Disease Senile Plaques
Kalback, Walter, Watson, M. Desiree, Kokjohn, Tyler A, Kuo, Yu-Min, Weiss, Nicole, Luehrs, Dean C, Lopez, John, Brune, Daniel, Sisodia, Sangram S, Staufenbiel, Matthias, Emmerling, Mark, Roher, Alex E
Published in Biochemistry (Easton) (22.01.2002)
Published in Biochemistry (Easton) (22.01.2002)
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Journal Article
Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease
Takahashi, M, Doré, S, Ferris, C D, Tomita, T, Sawa, A, Wolosker, H, Borchelt, D R, Iwatsubo, T, Kim, S H, Thinakaran, G, Sisodia, S S, Snyder, S H
Published in Neuron (Cambridge, Mass.) (01.11.2000)
Published in Neuron (Cambridge, Mass.) (01.11.2000)
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