Spatial segregation of gamma-secretase and substrates in distinct membrane domains
Vetrivel, Kulandaivelu S, Cheng, Haipeng, Kim, Seong-Hun, Chen, Ying, Barnes, Natalie Y, Parent, Angèle T, Sisodia, Sangram S, Thinakaran, Gopal
Published in The Journal of biological chemistry (08.07.2005)
Published in The Journal of biological chemistry (08.07.2005)
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Pen2 and Presenilin-1 Modulate the Dynamic Equilibrium of Presenilin-1 and Presenilin-2 γ-Secretase Complexes
Placanica, Lisa, Tarassishin, Leonid, Yang, Guangli, Peethumnongsin, Erica, Kim, Seong-Hun, Zheng, Hui, Sisodia, Sangram S., Li, Yue-Ming
Published in The Journal of biological chemistry (30.01.2009)
Published in The Journal of biological chemistry (30.01.2009)
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Infection and inflammation: New perspectives on Alzheimer's disease
Whitson, Heather E., Colton, Carol, El Khoury, Joseph, Gate, David, Goate, Alison, Heneka, Michael T., Kaddurah-Daouk, Rima, Klein, Robyn S., Shinohara, Mari L., Sisodia, Sangram, Spudich, Serena S., Stevens, Beth, Tanzi, Rudolph, Ting, Jenny P., Garden, Gwenn, Aiello, Alison, Chiba-Falek, Ornit, Heitman, Joseph, Johnson, Kim G., Luftig, Micah, Moseman, Ashley, Rawls, Jonathan, Shinohara, Mari L., Swanstrom, Ronald, Terrando, Niccolo
Published in Brain, behavior, & immunity. Health (01.07.2022)
Published in Brain, behavior, & immunity. Health (01.07.2022)
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Plug-Based Microfluidics with Defined Surface Chemistry to Miniaturize and Control Aggregation of Amyloidogenic Peptides
Meier, Matthias, Kennedy-Darling, Julia, Choi, Se Hoon, Norstrom, Eric M, Sisodia, Sangram S, Ismagilov, Rustem F
Published in Angewandte Chemie (International ed.) (01.01.2009)
Published in Angewandte Chemie (International ed.) (01.01.2009)
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Structure of γ-Secretase and Its Trimeric Pre-activation Intermediate by Single-particle Electron Microscopy
Renzi, Fabiana, Zhang, Xulun, Rice, William J., Torres-Arancivia, Celia, Gomez-Llorente, Yacob, Diaz, Ruben, Ahn, Kwangwook, Yu, Chunjiang, Li, Yue-Ming, Sisodia, Sangram S., Ubarretxena-Belandia, Iban
Published in The Journal of biological chemistry (17.06.2011)
Published in The Journal of biological chemistry (17.06.2011)
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Impairments in Fast Axonal Transport and Motor Neuron Deficits in Transgenic Mice Expressing Familial Alzheimer's Disease-Linked Mutant Presenilin 1
Lazarov, Orly, Morfini, Gerardo A, Pigino, Gustavo, Gadadhar, Archana, Chen, Xiangjun, Robinson, John, Ho, Hanson, Brady, Scott T, Sisodia, Sangram S
Published in The Journal of neuroscience (27.06.2007)
Published in The Journal of neuroscience (27.06.2007)
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Journal Article
Deficient Neurogenesis in Forebrain-Specific Presenilin-1 Knockout Mice Is Associated with Reduced Clearance of Hippocampal Memory Traces
Feng, Ruiben, Rampon, Claire, Tang, Ya-Ping, Shrom, David, Jin, Janice, Kyin, Maureen, Sopher, Bryce, Martin, George M, Kim, Seong-Hun, Langdon, Ronald B, Sisodia, Sangram S, Tsien, Joe Z
Published in Neuron (Cambridge, Mass.) (06.12.2001)
Published in Neuron (Cambridge, Mass.) (06.12.2001)
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Nuclear Inclusions in Glutamine Repeat Disorders: Are They Pernicious, Coincidental, or Beneficial?
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Book Review
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A Synthetic Antibody Fragment Targeting Nicastrin Affects Assembly and Trafficking of γ-Secretase
Zhang, Xulun, Hoey, Robert, Koide, Akiko, Dolios, Georgia, Paduch, Marcin, Nguyen, Phuong, Wu, Xianzhong, Li, Yueming, Wagner, Steven L., Wang, Rong, Koide, Shohei, Sisodia, Sangram S.
Published in The Journal of biological chemistry (12.12.2014)
Published in The Journal of biological chemistry (12.12.2014)
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Journal Article
Phospholipase D1 Corrects Impaired βAPP Trafficking and Neurite Outgrowth in Familial Alzheimer's Disease-Linked Presenilin-1 Mutant Neurons
Cai, Dongming, Zhong, Minghao, Wang, Runsheng, Netzer, William J., Shields, Dennis, Zheng, Hui, Sisodia, Sangram S., Foster, David A., Gorelick, Fred S., Xu, Huaxi, Greengard, Paul
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2006)
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Journal Article
Presenilin-1 Uses Phospholipase D1 as a Negative Regulator of β-Amyloid Formation
Cai, Dongming, Netzer, William J., Zhong, Minghao, Lin, Yixin, Du, Guangwei, Frohman, Michael, Foster, David A., Sisodia, Sangram S., Xu, Huaxi, Gorelick, Fred S., Greengard, Paul
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2006)
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Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides
Xu, H, Gouras, G K, Greenfield, J P, Vincent, B, Naslund, J, Mazzarelli, L, Fried, G, Jovanovic, J N, Seeger, M, Relkin, N R, Liao, F, Checler, F, Buxbaum, J D, Chait, B T, Thinakaran, G, Sisodia, S S, Wang, R, Greengard, P, Gandy, S
Published in Nature medicine (01.04.1998)
Published in Nature medicine (01.04.1998)
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Journal Article
Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins
Borchelt, David R, Ratovitski, Tamara, van Lare, Judy, Lee, Michael K, Gonzales, Vicki, Jenkins, Nancy A, Copeland, Neal G, Price, Donald L, Sisodia, Sangram S
Published in Neuron (Cambridge, Mass.) (01.10.1997)
Published in Neuron (Cambridge, Mass.) (01.10.1997)
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Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis
Tamboli, Irfan Y, Prager, Kai, Thal, Dietmar R, Thelen, Karin M, Dewachter, Ilse, Pietrzik, Claus U, St George-Hyslop, Peter, Sisodia, Sangram S, De Strooper, Bart, Heneka, Michael T, Filippov, Mikhail A, Müller, Ulrike, van Leuven, Fred, Lütjohann, Dieter, Walter, Jochen
Published in The Journal of neuroscience (12.11.2008)
Published in The Journal of neuroscience (12.11.2008)
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Journal Article
BMS-708,163 Targets Presenilin and Lacks Notch-Sparing Activity
Crump, Christina J, Castro, Suita V, Wang, Feng, Pozdnyakov, Nikolay, Ballard, T. Eric, Sisodia, Sangram S, Bales, Kelly R, Johnson, Douglas S, Li, Yue-Ming
Published in Biochemistry (Easton) (18.09.2012)
Published in Biochemistry (Easton) (18.09.2012)
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