Ultralarge Virtual Screening Identifies SARS-CoV‑2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses
Luttens, Andreas, Gullberg, Hjalmar, Abdurakhmanov, Eldar, Vo, Duy Duc, Akaberi, Dario, Talibov, Vladimir O, Nekhotiaeva, Natalia, Vangeel, Laura, De Jonghe, Steven, Jochmans, Dirk, Krambrich, Janina, Tas, Ali, Lundgren, Bo, Gravenfors, Ylva, Craig, Alexander J, Atilaw, Yoseph, Sandström, Anja, Moodie, Lindon W. K, Lundkvist, Åke, van Hemert, Martijn J, Neyts, Johan, Lennerstrand, Johan, Kihlberg, Jan, Sandberg, Kristian, Danielson, U. Helena, Carlsson, Jens
Published in Journal of the American Chemical Society (23.02.2022)
Published in Journal of the American Chemical Society (23.02.2022)
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Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries
Akaberi, Dario, Pourghasemi Lati, Monireh, Krambrich, Janina, Berger, Julia, Neilsen, Grace, Strandback, Emilia, Turunen, S. Pauliina, Wannberg, Johan, Gullberg, Hjalmar, Moche, Martin, Chinthakindi, Praveen Kumar, Nyman, Tomas, Sarafianos, Stefan G., Sandström, Anja, Järhult, Josef D., Sandberg, Kristian, Lundkvist, Åke, Verho, Oscar, Lennerstrand, Johan
Published in Antimicrobial agents and chemotherapy (28.08.2024)
Published in Antimicrobial agents and chemotherapy (28.08.2024)
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Antibacterial sulfonimidamide-based oligopeptides as type I signal peptidase inhibitors: Synthesis and biological evaluation
Benediktsdottir, Andrea, Lu, Lu, Cao, Sha, Zamaratski, Edouard, Karlén, Anders, Mowbray, Sherry L., Hughes, Diarmaid, Sandström, Anja
Published in European journal of medicinal chemistry (15.11.2021)
Published in European journal of medicinal chemistry (15.11.2021)
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Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors
Benediktsdottir, Andrea, Sooriyaarachchi, Sanjeewani, Cao, Sha, Ottosson, Nina E., Lindström, Stefan, Lundgren, Bo, Kloditz, Katharina, Lola, Daina, Bobileva, Olga, Loza, Einars, Hughes, Diarmaid, Jones, T. Alwyn, Mowbray, Sherry L., Zamaratski, Edouard, Sandström, Anja, Karlén, Anders
Published in European journal of medicinal chemistry (15.11.2024)
Published in European journal of medicinal chemistry (15.11.2024)
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Identification of a C2-symmetric diol based human immunodeficiency virus protease inhibitor targeting Zika virus NS2B-NS3 protease
Akaberi, Dario, Chinthakindi, Praveen K., Båhlström, Amanda, Palanisamy, Navaneethan, Sandström, Anja, Lundkvist, Åke, Lennerstrand, Johan
Published in Journal of biomolecular structure & dynamics (11.12.2020)
Published in Journal of biomolecular structure & dynamics (11.12.2020)
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Targeting the NS2B-NS3 protease of tick-borne encephalitis virus with pan-flaviviral protease inhibitors
Akaberi, Dario, Båhlström, Amanda, Chinthakindi, Praveen K., Nyman, Tomas, Sandström, Anja, Järhult, Josef D., Palanisamy, Navaneethan, Lundkvist, Åke, Lennerstrand, Johan
Published in Antiviral research (01.06.2021)
Published in Antiviral research (01.06.2021)
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Constrained H‑Phe-Phe-NH2 Analogues with High Affinity to the Substance P 1–7 Binding Site and with Improved Metabolic Stability and Cell Permeability
Fransson, Rebecca, Sköld, Christian, Kratz, Jadel M, Svensson, Richard, Artursson, Per, Nyberg, Fred, Hallberg, Mathias, Sandström, Anja
Published in Journal of medicinal chemistry (27.06.2013)
Published in Journal of medicinal chemistry (27.06.2013)
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Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket
Gising, Johan, Belfrage, Anna Karin, Alogheli, Hiba, Ehrenberg, Angelica, Åkerblom, Eva, Svensson, Richard, Artursson, Per, Karlén, Anders, Danielson, U. Helena, Larhed, Mats, Sandström, Anja
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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Impact of N-methylation of the substance P 1–7 amide on anti-allodynic effect in mice after peripheral administration
Skogh, Anna, Lesniak, Anna, Gaugaz, Fabienne Z., Svensson, Richard, Lindeberg, Gunnar, Fransson, Rebecca, Nyberg, Fred, Hallberg, Mathias, Sandström, Anja
Published in European journal of pharmaceutical sciences (15.11.2017)
Published in European journal of pharmaceutical sciences (15.11.2017)
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Pan-NS3 protease inhibitors of hepatitis C virus based on an R3-elongated pyrazinone scaffold
Belfrage, Anna Karin, Abdurakhmanov, Eldar, Åkerblom, Eva, Brandt, Peter, Alogheli, Hiba, Neyts, Johan, Danielson, U. Helena, Sandström, Anja
Published in European journal of medicinal chemistry (25.03.2018)
Published in European journal of medicinal chemistry (25.03.2018)
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Palladium-Catalyzed Carbonylation of Aryl Iodides with Sulfinamides
Belfrage, Anna Karin, Wakchaure, Prasad, Larhed, Mats, Sandström, Anja
Published in European journal of organic chemistry (01.11.2015)
Published in European journal of organic chemistry (01.11.2015)
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Journal Article
Importance of N- and C-terminal residues of substance P 1–7 for alleviating allodynia in mice after peripheral administration
Skogh, Anna, Lesniak, Anna, Gaugaz, Fabienne Z., Svensson, Richard, Lindeberg, Gunnar, Fransson, Rebecca, Nyberg, Fred, Hallberg, Mathias, Sandström, Anja
Published in European journal of pharmaceutical sciences (30.08.2017)
Published in European journal of pharmaceutical sciences (30.08.2017)
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Synthesis of Sulfonimidamide‐Based Amino Acid Building Blocks with Orthogonal Protecting Groups
Chinthakindi, Praveen K., Benediktsdottir, Andrea, Ibrahim, Ayah, Wared, Atta, Aurell, Carl‐Johan, Pettersen, Anna, Zamaratski, Edouard, Arvidsson, Per I., Chen, Yantao, Sandström, Anja
Published in European journal of organic chemistry (07.02.2019)
Published in European journal of organic chemistry (07.02.2019)
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