The molecular relationships between apoptosis, autophagy and necroptosis
Lalaoui, Najoua, Lindqvist, Lisa M., Sandow, Jarrod J., Ekert, Paul G.
Published in Seminars in cell & developmental biology (01.03.2015)
Published in Seminars in cell & developmental biology (01.03.2015)
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Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy
Bernardini, Jonathan P, Brouwer, Jason M, Tan, Iris KL, Sandow, Jarrod J, Huang, Shuai, Stafford, Che A, Bankovacki, Aleksandra, Riffkin, Christopher D, Wardak, Ahmad Z, Czabotar, Peter E, Lazarou, Michael, Dewson, Grant
Published in The EMBO journal (15.01.2019)
Published in The EMBO journal (15.01.2019)
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Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
Petrie, Emma J., Sandow, Jarrod J., Jacobsen, Annette V., Smith, Brian J., Griffin, Michael D. W., Lucet, Isabelle S., Dai, Weiwen, Young, Samuel N., Tanzer, Maria C., Wardak, Ahmad, Liang, Lung-Yu, Cowan, Angus D., Hildebrand, Joanne M., Kersten, Wilhelmus J. A., Lessene, Guillaume, Silke, John, Czabotar, Peter E., Webb, Andrew I., Murphy, James M.
Published in Nature communications (21.06.2018)
Published in Nature communications (21.06.2018)
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Arthroscopic rotator cuff repair using a transosseous knotless anchor (ATOK)
Sandow, Michael J., Schutz, Christine R.
Published in Journal of shoulder and elbow surgery (01.03.2020)
Published in Journal of shoulder and elbow surgery (01.03.2020)
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VDAC2 enables BAX to mediate apoptosis and limit tumor development
Chin, Hui San, Li, Mark X., Tan, Iris K. L., Ninnis, Robert L., Reljic, Boris, Scicluna, Kristen, Dagley, Laura F., Sandow, Jarrod J., Kelly, Gemma L., Samson, Andre L., Chappaz, Stephane, Khaw, Seong L., Chang, Catherine, Morokoff, Andrew, Brinkmann, Kerstin, Webb, Andrew, Hockings, Colin, Hall, Cathrine M., Kueh, Andrew J., Ryan, Michael T., Kluck, Ruth M., Bouillet, Philippe, Herold, Marco J., Gray, Daniel H. D., Huang, David C. S., van Delft, Mark F., Dewson, Grant
Published in Nature communications (26.11.2018)
Published in Nature communications (26.11.2018)
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Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis
Garnish, Sarah E., Meng, Yanxiang, Koide, Akiko, Sandow, Jarrod J., Denbaum, Eric, Jacobsen, Annette V., Yeung, Wayland, Samson, Andre L., Horne, Christopher R., Fitzgibbon, Cheree, Young, Samuel N., Smith, Phoebe P. C., Webb, Andrew I., Petrie, Emma J., Hildebrand, Joanne M., Kannan, Natarajan, Czabotar, Peter E., Koide, Shohei, Murphy, James M.
Published in Nature communications (13.04.2021)
Published in Nature communications (13.04.2021)
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Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis
Meng, Yanxiang, Davies, Katherine A., Fitzgibbon, Cheree, Young, Samuel N., Garnish, Sarah E., Horne, Christopher R., Luo, Cindy, Garnier, Jean-Marc, Liang, Lung-Yu, Cowan, Angus D., Samson, Andre L., Lessene, Guillaume, Sandow, Jarrod J., Czabotar, Peter E., Murphy, James M.
Published in Nature communications (22.11.2021)
Published in Nature communications (22.11.2021)
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Journal Article
Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies
Petrie, Emma J., Birkinshaw, Richard W., Koide, Akiko, Denbaum, Eric, Hildebrand, Joanne M., Garnish, Sarah E., Davies, Katherine A., Sandow, Jarrod J., Samson, Andre L., Gavin, Xavier, Fitzgibbon, Cheree, Young, Samuel N., Hennessy, Patrick J., Smith, Phoebe P. C., Webb, Andrew I., Czabotar, Peter E., Koide, Shohei, Murphy, James M.
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2020)
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Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex
Wong, Wilson, Huang, Rick, Menant, Sebastien, Hong, Chuan, Sandow, Jarrod J., Birkinshaw, Richard W., Healer, Julie, Hodder, Anthony N., Kanjee, Usheer, Tonkin, Christopher J., Heckmann, Denise, Soroka, Vladislav, Søgaard, Teit Max Moscote, Jørgensen, Thomas, Duraisingh, Manoj T., Czabotar, Peter E., de Jongh, Willem A., Tham, Wai-Hong, Webb, Andrew I., Yu, Zhiheng, Cowman, Alan F.
Published in Nature (London) (01.01.2019)
Published in Nature (London) (01.01.2019)
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Journal Article
Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3
Petrie, Emma J., Sandow, Jarrod J., Lehmann, Wil I.L., Liang, Lung-Yu, Coursier, Diane, Young, Samuel N., Kersten, Wilhelmus J.A., Fitzgibbon, Cheree, Samson, André L., Jacobsen, Annette V., Lowes, Kym N., Au, Amanda E., Jousset Sabroux, Hélène, Lalaoui, Najoua, Webb, Andrew I., Lessene, Guillaume, Manning, Gerard, Lucet, Isabelle S., Murphy, James M.
Published in Cell reports (Cambridge) (24.09.2019)
Published in Cell reports (Cambridge) (24.09.2019)
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How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor
Xu, Yibin, Kirk, Nicholas S., Venugopal, Hariprasad, Margetts, Mai B., Croll, Tristan I., Sandow, Jarrod J., Webb, Andrew I., Delaine, Carlie A., Forbes, Briony E., Lawrence, Michael C.
Published in Structure (London) (07.07.2020)
Published in Structure (London) (07.07.2020)
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Journal Article
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues
Davies, Katherine A., Fitzgibbon, Cheree, Young, Samuel N., Garnish, Sarah E., Yeung, Wayland, Coursier, Diane, Birkinshaw, Richard W., Sandow, Jarrod J., Lehmann, Wil I. L., Liang, Lung-Yu, Lucet, Isabelle S., Chalmers, James D., Patrick, Wayne M., Kannan, Natarajan, Petrie, Emma J., Czabotar, Peter E., Murphy, James M.
Published in Nature communications (19.06.2020)
Published in Nature communications (19.06.2020)
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BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association
Dengler, Michael A., Robin, Adeline Y., Gibson, Leonie, Li, Mark X., Sandow, Jarrod J., Iyer, Sweta, Webb, Andrew I., Westphal, Dana, Dewson, Grant, Adams, Jerry M.
Published in Cell reports (Cambridge) (09.04.2019)
Published in Cell reports (Cambridge) (09.04.2019)
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ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis
Sandow, J J, Dorstyn, L, O'Reilly, L A, Tailler, M, Kumar, S, Strasser, A, Ekert, P G
Published in Cell death and differentiation (01.03.2014)
Published in Cell death and differentiation (01.03.2014)
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Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix
Oliver, Michael R., Horne, Christopher R., Shrestha, Safal, Keown, Jeremy R., Liang, Lung-Yu, Young, Samuel N., Sandow, Jarrod J., Webb, Andrew I., Goldstone, David C., Lucet, Isabelle S., Kannan, Natarajan, Metcalf, Peter, Murphy, James M.
Published in Nature communications (12.02.2021)
Published in Nature communications (12.02.2021)
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Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid-binding residues
Chen, Kelan, Birkinshaw, Richard W, Gurzau, Alexandra D, Wanigasuriya, Iromi, Wang, Ruoyun, Iminitoff, Megan, Sandow, Jarrod J, Young, Samuel N, Hennessy, Patrick J, Willson, Tracy A, Heckmann, Denise A, Webb, Andrew I, Blewitt, Marnie E, Czabotar, Peter E, Murphy, James M
Published in Science signaling (16.06.2020)
Published in Science signaling (16.06.2020)
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Journal Article
Hemiarthroplasty vs total shoulder replacement for rotator cuff intact osteoarthritis: how do they fare after a decade?
Sandow, Michael J., BMBS, FRACS, David, Huw, BMBChr, FRCS, MCH(Orth), Bentall, Steven J., MBBS, FRACS
Published in Journal of shoulder and elbow surgery (01.07.2013)
Published in Journal of shoulder and elbow surgery (01.07.2013)
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