Gamma-secretase modulators: a promising route for the treatment of Alzheimer's disease
Nordvall, Gunnar, Lundkvist, Johan, Sandin, Johan
Published in Frontiers in molecular neuroscience (16.10.2023)
Published in Frontiers in molecular neuroscience (16.10.2023)
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Journal Article
Neuroprotective and Disease-Modifying Effects of the Triazinetrione ACD856, a Positive Allosteric Modulator of Trk-Receptors for the Treatment of Cognitive Dysfunction in Alzheimer's Disease
Parrado Fernandez, Cristina, Juric, Sanja, Backlund, Maria, Dahlström, Märta, Madjid, Nather, Lidell, Veronica, Rasti, Azita, Sandin, Johan, Nordvall, Gunnar, Forsell, Pontus
Published in International journal of molecular sciences (01.07.2023)
Published in International journal of molecular sciences (01.07.2023)
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Journal Article
Active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model
Oliveira, Daniel V, Coupland, Kirsten G, Shao, Wenchao, Jin, Shaobo, Del Gaudio, Francesca, Wang, Sailan, Fox, Rhys, Rutten, Julie W, Sandin, Johan, Zetterberg, Henrik, Lundkvist, Johan, Lesnik Oberstein, Saskia AJ, Lendahl, Urban, Karlström, Helena
Published in EMBO molecular medicine (08.02.2023)
Published in EMBO molecular medicine (08.02.2023)
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Journal Article
Identification of Novel Positive Allosteric Modulators of Neurotrophin Receptors for the Treatment of Cognitive Dysfunction
Dahlström, Märta, Madjid, Nather, Nordvall, Gunnar, Halldin, Magnus M, Vazquez-Juarez, Erika, Lindskog, Maria, Sandin, Johan, Winblad, Bengt, Eriksdotter, Maria, Forsell, Pontus
Published in Cells (Basel, Switzerland) (23.07.2021)
Published in Cells (Basel, Switzerland) (23.07.2021)
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Journal Article
5-Hydroxytryptamine 1A Receptor Blockade Facilitates Aversive Learning in Mice: Interactions with Cholinergic and Glutamatergic Mechanisms
Madjid, Nather, Tottie, Elin Elvander, Lüttgen, Maria, Meister, Björn, Sandin, Johan, Kuzmin, Alexander, Stiedl, Oliver, Ogren, Sven Ove
Published in The Journal of pharmacology and experimental therapeutics (01.02.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2006)
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Journal Article
Nociceptin/orphanin FQ metabolism and bioactive metabolites
Terenius, Lars, Sandin, Johan, Sakurada, Tsukasa
Published in Peptides (New York, N.Y. : 1980) (01.07.2000)
Published in Peptides (New York, N.Y. : 1980) (01.07.2000)
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Journal Article
Antidepressant effects of novel positive allosteric modulators of Trk-receptor mediated signaling – a potential therapeutic concept?
Madjid, Nather, Lidell, Veronica, Nordvall, Gunnar, Lindskog, Maria, Ögren, Sven-Ove, Forsell, Pontus, Sandin, Johan
Published in Psychopharmacology (01.08.2023)
Published in Psychopharmacology (01.08.2023)
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Journal Article
ACD856: A novel positive allosteric modulator of Trk‐signaling in clinical development for the treatment of Alzheimer’s disease
Nordvall, Gunnar, Madjid, Nather, Backlund, Maria, Halldin, Magnus, Rother, Matthias, Nilsson, Boel, Sandin, Johan, Forsell, Pontus
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Journal Article
Results From a Multiple Ascending Dose Study in Healthy Volunteers of ACD856, a Positive Modulator of Neurotrophin Trk‐Receptors
Önnestam, Kristin, Nilsson, Boel, Rother, Matthias, Rein‐Hedin, Erik, Bylund, Johan, Halldin, Magnus, Forsell, Pontus, Nordvall, Gunnar, Sandin, Johan, Segerdahl, Märta
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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Journal Article
AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans
Georgievska, Biljana, Sandin, Johan, Doherty, James, Mörtberg, Anette, Neelissen, Jan, Andersson, Anita, Gruber, Susanne, Nilsson, Yvonne, Schött, Pär, Arvidsson, Per I., Hellberg, Sven, Osswald, Gunilla, Berg, Stefan, Fälting, Johanna, Bhat, Ratan V.
Published in Journal of neurochemistry (01.05.2013)
Published in Journal of neurochemistry (01.05.2013)
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Journal Article
Broad analgesic activity of a novel, selective M1 agonist
Wood, Michael W., Martino, Giovanni, Coupal, Martin, Lindberg, Mattias, Schroeder, Patricia, Santhakumar, Vijayaratnam, Valiquette, Manon, Sandin, Johan, Widzowski, Daniel, Laird, Jennifer
Published in Neuropharmacology (01.09.2017)
Published in Neuropharmacology (01.09.2017)
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Journal Article
Agreement between frontal and occipital regional cerebral oxygen saturation in infants during surgery and general anesthesia an observational study
Jildenstål, Pether, Sandin, Johan, WarrènStomberg, Margareta, Pålsson, Jan, Ricksten, Sven‐Erik, Snygg, Johan
Published in Pediatric anesthesia (01.11.2019)
Published in Pediatric anesthesia (01.11.2019)
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Journal Article
Nociceptin and the NOP receptor in aversive learning in mice
Adem, Abdu, Madjid, Nather, Kahl, Ulrika, Holst, Sarah, Sadek, Bassem, Sandin, Johan, Terenius, Lars, Ögren, Sven Ove
Published in European neuropsychopharmacology (01.12.2017)
Published in European neuropsychopharmacology (01.12.2017)
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