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Stoeck, Alexander, Keller, Sascha, Riedle, Svenja, Sanderson, Michael P, Runz, Steffen, Le Naour, Francois, Gutwein, Paul, Ludwig, Andreas, Rubinstein, Eric, Altevogt, Peter
Published in Biochemical journal (01.02.2006)
Published in Biochemical journal (01.02.2006)
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The IGF1R/INSR Inhibitor BI 885578 Selectively Inhibits Growth of IGF2-Overexpressing Colorectal Cancer Tumors and Potentiates the Efficacy of Anti-VEGF Therapy
Sanderson, Michael P, Hofmann, Marco H, Garin-Chesa, Pilar, Schweifer, Norbert, Wernitznig, Andreas, Fischer, Stefan, Jeschko, Astrid, Meyer, Reiner, Moll, Jürgen, Pecina, Thomas, Arnhof, Heribert, Weyer-Czernilofsky, Ulrike, Zahn, Stephan K, Adolf, Günther R, Kraut, Norbert
Published in Molecular cancer therapeutics (01.10.2017)
Published in Molecular cancer therapeutics (01.10.2017)
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Generation of novel, secreted epidermal growth factor receptor (EGFR/ErbB1) isoforms via metalloprotease-dependent ectodomain shedding and exosome secretion
Sanderson, Michael P., Keller, Sascha, Alonso, Angel, Riedle, Svenja, Dempsey, Peter J., Altevogt, Peter
Published in Journal of cellular biochemistry (15.04.2008)
Published in Journal of cellular biochemistry (15.04.2008)
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SHP2 Inhibition Influences Therapeutic Response to Tepotinib in Tumors with MET Alterations
Pudelko, Linda, Jaehrling, Frank, Reusch, Christof, Viteri, Santiago, Stroh, Christopher, Linde, Nina, Sanderson, Michael P., Musch, Doreen, Lebrun, Catherine Jorand, Keil, Marina, Esdar, Christina, Blaukat, Andree, Rosell, Rafael, Schumacher, Karl Maria, Karachaliou, Niki
Published in iScience (18.12.2020)
Published in iScience (18.12.2020)
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ADAM10 Mediates Ectodomain Shedding of the Betacellulin Precursor Activated by p-Aminophenylmercuric Acetate and Extracellular Calcium Influx
Sanderson, Michael P., Erickson, Sarah N., Gough, Peter J., Garton, Kyle J., Wille, Paul T., Raines, Elaine W., Dunbar, Andrew J., Dempsey, Peter J.
Published in The Journal of biological chemistry (21.01.2005)
Published in The Journal of biological chemistry (21.01.2005)
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BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition
Hofmann, Marco H, Gmachl, Michael, Ramharter, Juergen, Savarese, Fabio, Gerlach, Daniel, Marszalek, Joseph R, Sanderson, Michael P, Kessler, Dirk, Trapani, Francesca, Arnhof, Heribert, Rumpel, Klaus, Botesteanu, Dana-Adriana, Ettmayer, Peter, Gerstberger, Thomas, Kofink, Christiane, Wunberg, Tobias, Zoephel, Andreas, Fu, Szu-Chin, Teh, Jessica L, Böttcher, Jark, Pototschnig, Nikolai, Schachinger, Franziska, Schipany, Katharina, Lieb, Simone, Vellano, Christopher P, O'Connell, Jonathan C, Mendes, Rachel L, Moll, Jurgen, Petronczki, Mark, Heffernan, Timothy P, Pearson, Mark, McConnell, Darryl B, Kraut, Norbert
Published in Cancer discovery (01.01.2021)
Published in Cancer discovery (01.01.2021)
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Translational PK/PD Modeling of Tumor Growth Inhibition and Target Inhibition to Support Dose Range Selection of the LMP7 Inhibitor M3258 in Relapsed/Refractory Multiple Myeloma
Lignet, Floriane, Esdar, Christina, Walter-Bausch, Gina, Friese-Hamim, Manja, Stinchi, Sofia, Drouin, Elise, El Bawab, Samer, Becker, Andreas D, Gimmi, Claude, Sanderson, Michael P, Rohdich, Felix
Published in The Journal of pharmacology and experimental therapeutics (01.01.2023)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2023)
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Syk and Lyn mediate distinct Syk phosphorylation events in FcɛRI-signal transduction: implications for regulation of IgE-mediated degranulation
Sanderson, Michael P, Wex, Eva, Kono, Takeshi, Uto, Katsuhiro, Schnapp, Andreas
Published in Molecular immunology (01.11.2010)
Published in Molecular immunology (01.11.2010)
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FGFR1 overexpression in non-small cell lung cancer is mediated by genetic and epigenetic mechanisms and is a determinant of FGFR1 inhibitor response
Bogatyrova, Olga, Mattsson, Johanna S.M., Ross, Edith M., Sanderson, Michael P., Backman, Max, Botling, Johan, Brunnström, Hans, Kurppa, Pinja, La Fleur, Linnéa, Strell, Carina, Wilm, Claudia, Zimmermann, Astrid, Esdar, Christina, Micke, Patrick
Published in European journal of cancer (1990) (01.07.2021)
Published in European journal of cancer (1990) (01.07.2021)
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Selective and Potent CDK8/19 Inhibitors Enhance NK-Cell Activity and Promote Tumor Surveillance
Hofmann, Marco H, Mani, Rajeswaran, Engelhardt, Harald, Impagnatiello, Maria A, Carotta, Sebastian, Kerenyi, Marc, Lorenzo-Herrero, Seila, Böttcher, Jark, Scharn, Dirk, Arnhof, Heribert, Zoephel, Andreas, Schnitzer, Renate, Gerstberger, Thomas, Sanderson, Michael P, Rajgolikar, Girish, Goswami, Swagata, Vasu, Sumithira, Ettmayer, Peter, Gonzalez, Segundo, Pearson, Mark, McConnell, Darryl B, Kraut, Norbert, Muthusamy, Natarajan, Moll, Jürgen
Published in Molecular cancer therapeutics (01.04.2020)
Published in Molecular cancer therapeutics (01.04.2020)
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M3258 Is a Selective Inhibitor of the Immunoproteasome Subunit LMP7 (β5i) Delivering Efficacy in Multiple Myeloma Models
Sanderson, Michael P, Friese-Hamim, Manja, Walter-Bausch, Gina, Busch, Michael, Gaus, Stefanie, Musil, Djordje, Rohdich, Felix, Zanelli, Ugo, Downey-Kopyscinski, Sondra L, Mitsiades, Constantine S, Schadt, Oliver, Klein, Markus, Esdar, Christina
Published in Molecular cancer therapeutics (01.08.2021)
Published in Molecular cancer therapeutics (01.08.2021)
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Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage
Aleksic, Tamara, Gray, Nicki, Wu, Xiaoning, Rieunier, Guillaume, Osher, Eliot, Mills, Jack, Verrill, Clare, Bryant, Richard J, Han, Cheng, Hutchinson, Kathryn, Lambert, Adam G, Kumar, Rajeev, Hamdy, Freddie C, Weyer-Czernilofsky, Ulrike, Sanderson, Michael P, Bogenrieder, Thomas, Taylor, Stephen, Macaulay, Valentine M
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Structure-Based Optimization and Discovery of M3258, a Specific Inhibitor of the Immunoproteasome Subunit LMP7 (β5i)
Klein, Markus, Busch, Michael, Friese-Hamim, Manja, Crosignani, Stefano, Fuchss, Thomas, Musil, Djordje, Rohdich, Felix, Sanderson, Michael P, Seenisamy, Jeyaprakashnarayanan, Walter-Bausch, Gina, Zanelli, Ugo, Hewitt, Philip, Esdar, Christina, Schadt, Oliver
Published in Journal of medicinal chemistry (22.07.2021)
Published in Journal of medicinal chemistry (22.07.2021)
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