Superior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy
Sánchez-Garrido, Miguel A., Serrano-López, Víctor, Ruiz-Pino, Francisco, Vázquez, María Jesús, Rodríguez-Martín, Andrea, Torres, Encarnación, Velasco, Inmaculada, Rodríguez, Ana Belén, Chicano-Gálvez, Eduardo, Mora-Ortiz, Marina, Ohlsson, Claes, Poutanen, Matti, Pinilla, Leonor, Gaytán, Francisco, Douros, Jonathan D., Yang, Bin, Müller, Timo D., DiMarchi, Richard D., Tschöp, Matthias H., Finan, Brian, Tena-Sempere, Manuel
Published in Nature communications (01.10.2024)
Published in Nature communications (01.10.2024)
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Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease
Finan, Brian, Clemmensen, Christoffer, Zhu, Zhimeng, Stemmer, Kerstin, Gauthier, Karine, Müller, Luisa, De Angelis, Meri, Moreth, Kristin, Neff, Frauke, Perez-Tilve, Diego, Fischer, Katrin, Lutter, Dominik, Sánchez-Garrido, Miguel A., Liu, Peng, Tuckermann, Jan, Malehmir, Mohsen, Healy, Marc E., Weber, Achim, Heikenwalder, Mathias, Jastroch, Martin, Kleinert, Maximilian, Jall, Sigrid, Brandt, Sara, Flamant, Frédéric, Schramm, Karl-Werner, Biebermann, Heike, Döring, Yvonne, Weber, Christian, Habegger, Kirk M., Keuper, Michaela, Gelfanov, Vasily, Liu, Fa, Köhrle, Josef, Rozman, Jan, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabě de Angelis, Martin, Hofmann, Susanna M., Yang, Bin, Tschöp, Matthias H., DiMarchi, Richard, Müller, Timo D.
Published in Cell (20.10.2016)
Published in Cell (20.10.2016)
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Sex-Biased Physiological Roles of NPFF1R, the Canonical Receptor of RFRP-3, in Food Intake and Metabolic Homeostasis Revealed by its Congenital Ablation in mice
Leon, Silvia, Velasco, Inmaculada, Vázquez, Maria J., Barroso, Alexia, Beiroa, Daniel, Heras, Violeta, Ruiz-Pino, Francisco, Manfredi-Lozano, Maria, Romero-Ruiz, Antonio, Sanchez-Garrido, Miguel A., Dieguez, Carlos, Pinilla, Leonor, Roa, Juan, Nogueiras, Ruben, Tena-Sempere, Manuel
Published in Metabolism, clinical and experimental (01.10.2018)
Published in Metabolism, clinical and experimental (01.10.2018)
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Journal Article
Early Metabolic Programming of Puberty Onset: Impact of Changes in Postnatal Feeding and Rearing Conditions on the Timing of Puberty and Development of the Hypothalamic Kisspeptin System
Castellano, Juan M, Bentsen, Agnete H, Sánchez-Garrido, Miguel A, Ruiz-Pino, Francisco, Romero, Magdalena, Garcia-Galiano, David, Aguilar, Enrique, Pinilla, Leonor, Diéguez, Carlos, Mikkelsen, Jens D, Tena-Sempere, Manuel
Published in Endocrinology (Philadelphia) (01.09.2011)
Published in Endocrinology (Philadelphia) (01.09.2011)
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Journal Article
Role of neurokinin B in the control of female puberty and its modulation by metabolic status
Navarro, Víctor M, Ruiz-Pino, Francisco, Sánchez-Garrido, Miguel A, García-Galiano, David, Hobbs, Samuel J, Manfredi-Lozano, María, León, Silvia, Sangiao-Alvarellos, Susana, Castellano, Juan M, Clifton, Donald K, Pinilla, Leonor, Steiner, Robert A, Tena-Sempere, Manuel
Published in The Journal of neuroscience (15.02.2012)
Published in The Journal of neuroscience (15.02.2012)
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Journal Article
Renaissance of leptin for obesity therapy
Quarta, Carmelo, Sánchez-Garrido, Miguel A., Tschöp, Matthias H., Clemmensen, Christoffer
Published in Diabetologia (01.05.2016)
Published in Diabetologia (01.05.2016)
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Journal Article
Book Review
Early nutritional changes induce sexually dimorphic long-term effects on body weight gain and the response to sucrose intake in adult rats
Fuente-Martín, Esther, Granado, Miriam, García-Cáceres, Cristina, Sanchez-Garrido, Miguel A, Frago, Laura M, Tena-Sempere, Manuel, Argente, Jesús, Chowen, Julie A
Published in Metabolism, clinical and experimental (01.06.2012)
Published in Metabolism, clinical and experimental (01.06.2012)
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Journal Article
Defining a novel leptin–melanocortin–kisspeptin pathway involved in the metabolic control of puberty
Manfredi-Lozano, Maria, Roa, Juan, Ruiz-Pino, Francisco, Piet, Richard, Garcia-Galiano, David, Pineda, Rafael, Zamora, Aurora, Leon, Silvia, Sanchez-Garrido, Miguel A, Romero-Ruiz, Antonio, Dieguez, Carlos, Vazquez, Maria Jesus, Herbison, Allan E, Pinilla, Leonor, Tena-Sempere, Manuel
Published in Molecular metabolism (Germany) (01.10.2016)
Published in Molecular metabolism (Germany) (01.10.2016)
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Journal Article
VCE-004.8, A Multitarget Cannabinoquinone, Attenuates Adipogenesis and Prevents Diet-Induced Obesity
Palomares, Belen, Ruiz-Pino, Francisco, Navarrete, Carmen, Velasco, Inmaculada, Sánchez-Garrido, Miguel A., Jimenez-Jimenez, Carla, Pavicic, Carolina, Vazquez, Maria J., Appendino, Giovanni, Bellido, M. Luz, Calzado, Marco A., Tena-Sempere, Manuel, Muñoz, Eduardo
Published in Scientific reports (31.10.2018)
Published in Scientific reports (31.10.2018)
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Journal Article
GLP-1/glucagon receptor co-agonism for treatment of obesity
Sánchez-Garrido, Miguel A., Brandt, Sara J., Clemmensen, Christoffer, Müller, Timo D., DiMarchi, Richard D., Tschöp, Matthias H.
Published in Diabetologia (01.10.2017)
Published in Diabetologia (01.10.2017)
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Journal Article
Early postnatal overnutrition increases adipose tissue accrual in response to a sucrose-enriched diet
Fuente-Martín, Esther, García-Cáceres, Cristina, Granado, Miriam, Sánchez-Garrido, Miguel A, Tena-Sempere, Manuel, Frago, Laura M, Argente, Jesús, Chowen, Julie A
Published in American journal of physiology: endocrinology and metabolism (15.06.2012)
Published in American journal of physiology: endocrinology and metabolism (15.06.2012)
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Journal Article
IL-6 and IGF-1 are independent prognostic factors of liver steatosis and non-alcoholic steatohepatitis in morbidly obese patients
García-Galiano, David, Sánchez-Garrido, Miguel A, Espejo, Isabel, Montero, José Luis, Costán, Guadalupe, Marchal, Trinidad, Membrives, Antonio, Gallardo-Valverde, José M, Muñoz-Castañeda, Juan R, Arévalo, Eugenio, De la Mata, Manuel, Muntané, Jordi
Published in Obesity surgery (01.04.2007)
Published in Obesity surgery (01.04.2007)
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Tetrahydrocannabinolic acid A (THCA-A) reduces adiposity and prevents metabolic disease caused by diet-induced obesity
Palomares, Belén, Ruiz-Pino, Francisco, Garrido-Rodriguez, Martin, Eugenia Prados, M., Sánchez-Garrido, Miguel A., Velasco, Inmaculada, Vazquez, María J., Nadal, Xavier, Ferreiro-Vera, Carlos, Morrugares, Rosario, Appendino, Giovanni, Calzado, Marco A, Tena-Sempere, Manuel, Muñoz, Eduardo
Published in Biochemical pharmacology (01.01.2020)
Published in Biochemical pharmacology (01.01.2020)
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Neonatal Overnutrition Increases Testicular Size and Expression of Luteinizing Hormone β-Subunit in Peripubertal Male Rats
Argente-Arizón, Pilar, Castro-González, David, Díaz, Francisca, Fernández-Gómez, María J, Sánchez-Garrido, Miguel A, Tena-Sempere, Manuel, Argente, Jesús, Chowen, Julie A
Published in Frontiers in endocrinology (Lausanne) (13.04.2018)
Published in Frontiers in endocrinology (Lausanne) (13.04.2018)
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Journal Article
Gonadal hormone-dependent vs. -independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis
Velasco, Inmaculada, León, Silvia, Barroso, Alexia, Ruiz-Pino, Francisco, Heras, Violeta, Torres, Encarnación, León, María, Ruohonen, Suvi T., García-Galiano, David, Romero-Ruiz, Antonio, Sánchez-Garrido, Miguel A., Ohlsson, Claes, Castellano, Juan M., Roa, Juan, Poutanen, Matti, Pinilla, Leonor, Vázquez, María J., Tena-Sempere, Manuel
Published in Metabolism, clinical and experimental (01.09.2019)
Published in Metabolism, clinical and experimental (01.09.2019)
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Journal Article
Interplay between gonadal hormones and postnatal overfeeding in defining sex-dependent differences in gut microbiota architecture
Santos-Marcos, Jose A, Barroso, Alexia, Rangel-Zuñiga, Oriol A, Perdices-Lopez, Cecilia, Haro, Carmen, Sanchez-Garrido, Miguel A, Molina-Abril, Helena, Ohlsson, Claes, Perez-Martinez, Pablo, Poutanen, Matti, Lopez-Miranda, Jose, Perez-Jimenez, Francisco, Tena-Sempere, Manuel, Camargo, Antonio
Published in Aging (Albany, NY.) (27.10.2020)
Published in Aging (Albany, NY.) (27.10.2020)
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Journal Article
Targeted pharmacological therapy restores β-cell function for diabetes remission
Sachs, Stephan, Bastidas-Ponce, Aimée, Tritschler, Sophie, Bakhti, Mostafa, Böttcher, Anika, Sánchez-Garrido, Miguel A, Tarquis-Medina, Marta, Kleinert, Maximilian, Fischer, Katrin, Jall, Sigrid, Harger, Alexandra, Bader, Erik, Roscioni, Sara, Ussar, Siegfried, Feuchtinger, Annette, Yesildag, Burcak, Neelakandhan, Aparna, Jensen, Christine B, Cornu, Marion, Yang, Bin, Finan, Brian, DiMarchi, Richard D, Tschöp, Matthias H, Theis, Fabian J, Hofmann, Susanna M, Müller, Timo D, Lickert, Heiko
Published in Nature metabolism (01.02.2020)
Published in Nature metabolism (01.02.2020)
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Journal Article
Metabolic and Gonadotropic Impact of Sequential Obesogenic Insults in the Female: Influence of the Loss of Ovarian Secretion
Sánchez-Garrido, Miguel A, Ruiz-Pino, Francisco, Manfredi-Lozano, María, Leon, Silvia, Heras, Violeta, Castellano, Juan M, Castaño, Justo P, Luque, Raúl M, Vázquez, María J, Roa, Juan, Romero-Ruiz, Antonio, Diéguez, Carlos, Pinilla, Leonor, Tena-Sempere, Manuel
Published in Endocrinology (Philadelphia) (01.08.2015)
Published in Endocrinology (Philadelphia) (01.08.2015)
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