Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid‑4 (TRPV4)
Brnardic, Edward J, Ye, Guosen, Brooks, Carl, Donatelli, Carla, Barton, Linda, McAtee, Jeff, Sanchez, Robert M, Shu, Arthur, Erhard, Karl, Terrell, Lamont, Graczyk-Millbrandt, Grazyna, He, Yanan, Costell, Melissa H, Behm, David J, Roethke, Theresa, Stoy, Patrick, Holt, Dennis A, Lawhorn, Brian G
Published in Journal of medicinal chemistry (08.11.2018)
Published in Journal of medicinal chemistry (08.11.2018)
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Discovery of GSK3527497: A Candidate for the Inhibition of Transient Receptor Potential Vanilloid‑4 (TRPV4)
Brooks, Carl A, Barton, Linda S, Behm, David J, Brnardic, Edward J, Costell, Melissa H, Holt, Dennis A, Jolivette, Larry J, Matthews, Jay M, McAtee, John J, McCleland, Brent W, Patterson, Jaclyn R, Pero, Joseph E, Rivero, Ralph A, Roethke, Theresa J, Sanchez, Robert M, Shenje, Raynold, Terrell, Lamont R, Lawhorn, Brian G
Published in Journal of medicinal chemistry (24.10.2019)
Published in Journal of medicinal chemistry (24.10.2019)
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Synthesis and structure–activity relationships of 1,2,4-triazolo[1,5-a]pyrimidin-7(3H)-ones as novel series of potent β isoform selective phosphatidylinositol 3-kinase inhibitors
Sanchez, Robert M., Erhard, Karl, Hardwicke, Mary Ann, Lin, Hong, McSurdy-Freed, Jeanelle, Plant, Ramona, Raha, Kaushik, Rominger, Cynthia M., Schaber, Michael D., Spengler, Michael D., Moore, Michael L., Yu, Hongyi, Luengo, Juan I., Tedesco, Rosanna, Rivero, Ralph A.
Published in Bioorganic & medicinal chemistry letters (01.05.2012)
Published in Bioorganic & medicinal chemistry letters (01.05.2012)
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Synthesis and structure–activity relationships of imidazo[1,2-a]pyrimidin-5(1H)-ones as a novel series of beta isoform selective phosphatidylinositol 3-kinase inhibitors
Lin, Hong, Erhard, Karl, Hardwicke, Mary Ann, Luengo, Juan I., Mack, James F., McSurdy-Freed, Jeanelle, Plant, Ramona, Raha, Kaushik, Rominger, Cynthia M., Sanchez, Robert M., Schaber, Michael D., Schulz, Mark J., Spengler, Michael D., Tedesco, Rosanna, Xie, Ren, Zeng, Jin J., Rivero, Ralph A.
Published in Bioorganic & medicinal chemistry letters (15.03.2012)
Published in Bioorganic & medicinal chemistry letters (15.03.2012)
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Journal Article
Fast halogen abstractions from alkyl halides by alkyl radicals. Quantitation of the processes occurring in and a caveat for studies employing alkyl halide mechanistic probes
Newcomb, Martin, Sanchez, Robert M, Kaplan, Jere
Published in Journal of the American Chemical Society (01.02.1987)
Published in Journal of the American Chemical Society (01.02.1987)
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Journal Article
An efficient and practical synthesis of 2,4-substituted pyrido[4,3-d]pyrimidin-5(6H)-ones
Tian, Xinrong, Suarez, Dominic P., Li, William Hoi Hong, McSherry, Allison K., Sanchez, Robert M., Moore, Michael L., Axten, Jeffrey M.
Published in Tetrahedron letters (05.12.2019)
Published in Tetrahedron letters (05.12.2019)
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Journal Article
A Convenient synthesis of the, conformationally constrained amino acid 5,5-dimethylproline
Magaard, Victoria W., Sanchez, Robert M., Bean, John W., Moore, Michael L.
Published in Tetrahedron letters (15.01.1993)
Published in Tetrahedron letters (15.01.1993)
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