A crucial role for the C‐terminal domain of exported protein 1 during the mosquito and hepatic stages of the Plasmodium berghei life cycle
Wolanin, Kamil, Fontinha, Diana, Sanches‐Vaz, Margarida, Nyboer, Britta, Heiss, Kirsten, Mueller, Ann‐Kristin, Prudêncio, Miguel
Published in Cellular microbiology (01.10.2019)
Published in Cellular microbiology (01.10.2019)
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Journal Article
Sleeping sickness is a circadian disorder
Rijo-Ferreira, Filipa, Carvalho, Tânia, Afonso, Cristina, Sanches-Vaz, Margarida, Costa, Rui M, Figueiredo, Luísa M, Takahashi, Joseph S
Published in Nature communications (04.01.2018)
Published in Nature communications (04.01.2018)
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Journal Article
Trypanosoma brucei infection protects mice against malaria
Sanches-Vaz, Margarida, Temporão, Adriana, Luis, Rafael, Nunes-Cabaço, Helena, Mendes, António M, Goellner, Sarah, Carvalho, Tânia, Figueiredo, Luisa M, Prudêncio, Miguel
Published in PLoS pathogens (08.11.2019)
Published in PLoS pathogens (08.11.2019)
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Journal Article
African trypanosomes expressing multiple VSGs are rapidly eliminated by the host immune system
Aresta-Branco, Francisco, Sanches-Vaz, Margarida, Bento, Fabio, Rodrigues, João A., Figueiredo, Luisa M.
Published in Proceedings of the National Academy of Sciences - PNAS (08.10.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (08.10.2019)
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Journal Article
Discovery of spirooxadiazoline oxindoles with dual-stage antimalarial activity
Lopes, Elizabeth A., Mestre, Raquel, Fontinha, Diana, Legac, Jenny, Pei, Jinxin V., Sanches-Vaz, Margarida, Mori, Mattia, Lehane, Adele M., Rosenthal, Philip J., Prudêncio, Miguel, Santos, Maria M.M.
Published in European journal of medicinal chemistry (05.06.2022)
Published in European journal of medicinal chemistry (05.06.2022)
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Journal Article
Plasmodium berghei EXP-1 interacts with host Apolipoprotein H during Plasmodium liver-stage development
Cunha, Cláudia Sá e, Nyboer, Britta, Heiss, Kirsten, Sanches-Vaz, Margarida, Fontinha, Diana, Wiedtke, Ellen, Grimm, Dirk, Przyborski, Jude Marek, Mota, Maria M., Prudêncio, Miguel, Mueller, Ann-Kristin
Published in Proceedings of the National Academy of Sciences - PNAS (14.02.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (14.02.2017)
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Journal Article
Endoperoxide-8-aminoquinoline hybrids as dual-stage antimalarial agents with enhanced metabolic stability
Capela, Rita, Magalhães, Joana, Miranda, Daniela, Machado, Marta, Sanches-Vaz, Margarida, Albuquerque, Inês S., Sharma, Moni, Gut, Jiri, Rosenthal, Philip J., Frade, Raquel, Perry, Maria J., Moreira, Rui, Prudêncio, Miguel, Lopes, Francisca
Published in European journal of medicinal chemistry (10.04.2018)
Published in European journal of medicinal chemistry (10.04.2018)
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Journal Article
Coupling the cell-penetrating peptides transportan and transportan 10 to primaquine enhances its activity against liver-stage malaria parasites
Aguiar, Luísa, Machado, Marta, Sanches-Vaz, Margarida, Prudêncio, Miguel, Vale, Nuno, Gomes, Paula
Published in MedChemComm (01.02.2019)
Published in MedChemComm (01.02.2019)
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Journal Article
Structure–Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N‑Aryl-3-trifluoromethyl Pyrido[1,2‑a]benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria
Mayoka, Godfrey, Njoroge, Mathew, Okombo, John, Gibhard, Liezl, Sanches-Vaz, Margarida, Fontinha, Diana, Birkholtz, Lyn-Marie, Reader, Janette, van der Watt, Mariëtte, Coetzer, Theresa L, Lauterbach, Sonja, Churchyard, Alisje, Bezuidenhout, Belinda, Egan, Timothy J, Yeates, Clive, Wittlin, Sergio, Prudêncio, Miguel, Chibale, Kelly
Published in Journal of medicinal chemistry (24.01.2019)
Published in Journal of medicinal chemistry (24.01.2019)
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Journal Article
Multistage Antiplasmodium Activity of Astemizole Analogues and Inhibition of Hemozoin Formation as a Contributor to Their Mode of Action
Kumar, Malkeet, Okombo, John, Mambwe, Dickson, Taylor, Dale, Lawrence, Nina, Reader, Janette, van der Watt, Mariëtte, Fontinha, Diana, Sanches-Vaz, Margarida, Bezuidenhout, Belinda C, Lauterbach, Sonja B, Liebenberg, Dale, Birkholtz, Lyn-Marie, Coetzer, Theresa L, Prudêncio, Miguel, Egan, Timothy J, Wittlin, Sergio, Chibale, Kelly
Published in ACS infectious diseases (08.02.2019)
Published in ACS infectious diseases (08.02.2019)
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