Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function
Palanikumar, L., Karpauskaite, Laura, Al-Sayegh, Mohamed, Chehade, Ibrahim, Alam, Maheen, Hassan, Sarah, Maity, Debabrata, Ali, Liaqat, Kalmouni, Mona, Hunashal, Yamanappa, Ahmed, Jemil, Houhou, Tatiana, Karapetyan, Shake, Falls, Zackary, Samudrala, Ram, Pasricha, Renu, Esposito, Gennaro, Afzal, Ahmed J., Hamilton, Andrew D., Kumar, Sunil, Magzoub, Mazin
Published in Nature communications (25.06.2021)
Published in Nature communications (25.06.2021)
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Journal Article
Effective holistic characterization of small molecule effects using heterogeneous biological networks
Mangione, William, Falls, Zackary, Samudrala, Ram
Published in Frontiers in pharmacology (26.04.2023)
Published in Frontiers in pharmacology (26.04.2023)
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Journal Article
Optimal COVID-19 therapeutic candidate discovery using the CANDO platform
Mangione, William, Falls, Zackary, Samudrala, Ram
Published in Frontiers in pharmacology (25.08.2022)
Published in Frontiers in pharmacology (25.08.2022)
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Journal Article
Identifying Protein Features and Pathways Responsible for Toxicity Using Machine Learning and Tox21: Implications for Predictive Toxicology
Moukheiber, Lama, Mangione, William, Moukheiber, Mira, Maleki, Saeed, Falls, Zackary, Gao, Mingchen, Samudrala, Ram
Published in Molecules (Basel, Switzerland) (08.05.2022)
Published in Molecules (Basel, Switzerland) (08.05.2022)
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Journal Article
A Deep-Learning Proteomic-Scale Approach for Drug Design
Overhoff, Brennan, Falls, Zackary, Mangione, William, Samudrala, Ram
Published in Pharmaceuticals (Basel, Switzerland) (07.12.2021)
Published in Pharmaceuticals (Basel, Switzerland) (07.12.2021)
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Journal Article
Combating Ebola with Repurposed Therapeutics Using the CANDO Platform
Chopra, Gaurav, Kaushik, Sashank, Elkin, Peter L, Samudrala, Ram
Published in Molecules (Basel, Switzerland) (25.11.2016)
Published in Molecules (Basel, Switzerland) (25.11.2016)
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Journal Article
Exploration of interaction scoring criteria in the CANDO platform
Falls, Zackary, Mangione, William, Schuler, James, Samudrala, Ram
Published in BMC research notes (07.06.2019)
Published in BMC research notes (07.06.2019)
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Journal Article
Data access for the 1,000 Plants (1KP) project
Matasci, Naim, Hung, Ling-Hong, Yan, Zhixiang, Carpenter, Eric J, Wickett, Norman J, Mirarab, Siavash, Nguyen, Nam, Warnow, Tandy, Ayyampalayam, Saravanaraj, Barker, Michael, Burleigh, J Gordon, Gitzendanner, Matthew A, Wafula, Eric, Der, Joshua P, dePamphilis, Claude W, Roure, Béatrice, Philippe, Hervé, Ruhfel, Brad R, Miles, Nicholas W, Graham, Sean W, Mathews, Sarah, Surek, Barbara, Melkonian, Michael, Soltis, Douglas E, Soltis, Pamela S, Rothfels, Carl, Pokorny, Lisa, Shaw, Jonathan A, DeGironimo, Lisa, Stevenson, Dennis W, Villarreal, Juan Carlos, Chen, Tao, Kutchan, Toni M, Rolf, Megan, Baucom, Regina S, Deyholos, Michael K, Samudrala, Ram, Tian, Zhijian, Wu, Xiaolei, Sun, Xiao, Zhang, Yong, Wang, Jun, Leebens-Mack, Jim, Wong, Gane Ka-Shu
Published in Gigascience (27.10.2014)
Published in Gigascience (27.10.2014)
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Journal Article
CANDO and the infinite drug discovery frontier
Minie, Mark, Chopra, Gaurav, Sethi, Geetika, Horst, Jeremy, White, George, Roy, Ambrish, Hatti, Kaushik, Samudrala, Ram
Published in Drug discovery today (01.09.2014)
Published in Drug discovery today (01.09.2014)
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Journal Article
Accurate Prediction of Inhibitor Binding to HIV-1 Protease Using CANDOCK
Falls, Zackary, Fine, Jonathan, Chopra, Gaurav, Samudrala, Ram
Published in Frontiers in chemistry (17.01.2022)
Published in Frontiers in chemistry (17.01.2022)
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Journal Article
Multiscale Analysis and Validation of Effective Drug Combinations Targeting Driver KRAS Mutations in Non-Small Cell Lung Cancer
Bruggemann, Liana, Falls, Zackary, Mangione, William, Schwartz, Stanley A, Battaglia, Sebastiano, Aalinkeel, Ravikumar, Mahajan, Supriya D, Samudrala, Ram
Published in International journal of molecular sciences (05.01.2023)
Published in International journal of molecular sciences (05.01.2023)
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Journal Article
A novel knowledge-based approach to design inorganic-binding peptides
Oren, Ersin Emre, Tamerler, Candan, Sahin, Deniz, Hnilova, Marketa, Seker, Urartu Ozgur Safak, Sarikaya, Mehmet, Samudrala, Ram
Published in Bioinformatics (01.11.2007)
Published in Bioinformatics (01.11.2007)
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Journal Article