Improvement of sensory deficits in fragile X mice by increasing cortical interneuron activity after the critical period
Kourdougli, Nazim, Suresh, Anand, Liu, Benjamin, Juarez, Pablo, Lin, Ashley, Chung, David T., Graven Sams, Anette, Gandal, Michael J., Martínez-Cerdeño, Verónica, Buonomano, Dean V., Hall, Benjamin J., Mombereau, Cédric, Portera-Cailliau, Carlos
Published in Neuron (Cambridge, Mass.) (20.09.2023)
Published in Neuron (Cambridge, Mass.) (20.09.2023)
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Journal Article
Hit-to-lead optimization of a series of carboxamides of ethyl 2-amino-4-phenylthiazole-5-carboxylates as novel adenosine A2A receptor antagonists
GRAVEN SAMS, Anette, MIKKELSEN, Gitte Kobberøe, LARSEN, Mogens, TORUP, Lars, BRENNUM, Lise Tottrup, SCHRØDER, Tenna Juul, BANG-ANDERSEN, Benny
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
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Journal Article
KV7 칼륨 채널 오프너로서의 알코올 유도체
CHEN SHU HUI, ROTTLAENDER MARIO, LARSEN KRESTIAN, SAMS ANETTE GRAVEN, WANG XIAOFANG, DAS DEBASIS, HONG JIAN
Year of Publication 31.03.2022
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Year of Publication 31.03.2022
Patent
Kv3 칼륨 채널 활성제로서의 아릴설포닐피롤카복사미드 유도체
SAMS ANETTE GRAVEN, RASMUSSEN LARS KYHN, FLEMING PAUL ROBERT, YU WANWAN
Year of Publication 08.07.2021
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Year of Publication 08.07.2021
Patent
In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders
Grupe, Morten, Bentzen, Bo Hjorth, Benned-Jensen, Tau, Nielsen, Vibeke, Frederiksen, Kristen, Jensen, Henrik Sindal, Jacobsen, Anne-Marie, Skibsbye, Lasse, Sams, Anette Graven, Grunnet, Morten, Rottländer, Mario, Bastlund, Jesper Frank
Published in European journal of pharmacology (15.11.2020)
Published in European journal of pharmacology (15.11.2020)
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Journal Article
2-SUBSTITUTED-ETHYNYLTHIAZOLE DERIVATIVES AND USES OF SAME
GRENON MICHEL, SAMS ANETTE GRAVEN, HOPPER ALLEN, MIKKELSEN GITTE KOBBEROEE, PACKIARAJAN MATHIVANAN
Year of Publication 08.08.2012
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Year of Publication 08.08.2012
Patent
Efficacy switching SAR of mGluR5 allosteric modulators: Highly potent positive and negative modulators from one chemotype
Sams, Anette Graven, Mikkelsen, Gitte Kobberøe, Brodbeck, Robbin M., Pu, Xiaosui, Ritzén, Andreas
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
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Journal Article
Hit-to-lead investigation of a series of novel combined dopamine D-2 and muscarinic M-1 receptor ligands with putative antipsychotic and pro-cognitive potential
Sams, Anette Graven, Larsen, Krestian, Mikkelsen, Gitte Kobberoe, Hentzer, Morten, Christoffersen, Claus Tornby, Jensen, Klaus Gjervig, Frederiksen, Kristen, Bang-Andersen, Benny
Published in Bioorganic & medicinal chemistry letters (01.08.2012)
Published in Bioorganic & medicinal chemistry letters (01.08.2012)
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Journal Article
Hit-to-lead investigation of a series of novel combined dopamine D2 and muscarinic M1 receptor ligands with putative antipsychotic and pro-cognitive potential
Sams, Anette Graven, Larsen, Krestian, Mikkelsen, Gitte Kobberøe, Hentzer, Morten, Christoffersen, Claus Tornby, Jensen, Klaus Gjervig, Frederiksen, Kristen, Bang-Andersen, Benny
Published in Bioorganic & medicinal chemistry letters (01.08.2012)
Published in Bioorganic & medicinal chemistry letters (01.08.2012)
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Journal Article
Hit-to-lead optimization of a series of carboxamides of ethyl 2-amino-4-phenylthiazole-5-carboxylates as novel adenosine A 2A receptor antagonists
Sams, Anette Graven, Mikkelsen, Gitte Kobberøe, Larsen, Mogens, Torup, Lars, Brennum, Lise Tøttrup, Schrøder, Tenna Juul, Bang-Andersen, Benny
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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Journal Article
N-thiazol-2-yl-benzamide derivatives
GITTE MIKKELSEN, ANETTE GRAVEN SAMS, MOGENS LARSEN, ANETTE, GRAVEN SAMS
Year of Publication 06.05.2005
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Year of Publication 06.05.2005
Patent
ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS
Wang, Xiaofang, Rottlander, Mario, Hong, Jian, Sams, Anette Graven, Chen, Shu Hui, Larsen, Krestian, Das, Debasis
Year of Publication 03.10.2024
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Year of Publication 03.10.2024
Patent
ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS
SAMS, Anette, Graven, WANG, Xiaofang, CHEN, Shu, Hui, LARSEN, Krestian, DAS, Debasis, HONG, Jian, ROTTLÄNDER, Mario
Year of Publication 02.10.2024
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Year of Publication 02.10.2024
Patent
ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS
SAMS, Anette, Graven, WANG, Xiaofang, CHEN, Shu, Hui, LARSEN, Krestian, DAS, Debasis, HONG, Jian, ROTTLÄNDER, Mario
Year of Publication 10.06.2024
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Year of Publication 10.06.2024
Patent
ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS
ANETTE GRAVEN SAMS, MARIO ROTTLÄNDER, KRESTIAN LARSEN, XIAOFANG WANG, DEBASIS DAS, SHU HUI CHEN, JIAN HONG
Year of Publication 24.04.2024
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Year of Publication 24.04.2024
Patent
ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS
Sams, Anette, Graven, Wang, Xiaofang, Chen, Shu, Hui, Rottländer, Mario, Hong, Jian, Das, Debasis
Year of Publication 10.11.2023
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Year of Publication 10.11.2023
Patent
ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS
CHEN, SHU HUI, WANG, XIAOFANG, ROTTLÄNDER, MARIO, SAMS, ANETTE GRAVEN, DAS, DEBASIS, HONG, JIAN
Year of Publication 06.11.2023
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Year of Publication 06.11.2023
Patent