Abstract 1713: Novel, potent and orally bioavailable small molecule CD73 inhibitors for cancer immunotherapy
Venkateshappa, Chandregowda, Narayanan, Kishore, Kothandaraman, Prasath, Priyadarshani, Garima, Nair, Rashmi, Goyal, Megha, Ahuja, Vijay Kamal, Dadhania, Sagar, Aravind, AB, Samiulla, DS, Daginakkatte, Girish, Antony, Thomas, Nellore, Kavitha, Panigrahi, Sunil, Chikkanna, Dinesh, Samajdar, Susanta, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer
He, Tongchen, Cheng, Caleb, Qiao, Yuanyuan, Cho, Hanbyul, Young, Eleanor, Mannan, Rahul, Mahapatra, Somnath, Miner, Stephanie J, Zheng, Yang, Kim, NamHoon, Zeng, Victoria Z, Wisniewski, Jasmine P, Hou, Siyu, Jackson, Bailey, Cao, Xuhong, Su, Fengyun, Wang, Rui, Chang, Yu, Kuila, Bilash, Mukherjee, Subhendu, Dukare, Sandeep, Aithal, Kiran B, D S, Samiulla, Abbineni, Chandrasekhar, Vaishampayan, Ulka, Lyssiotis, Costas A, Parolia, Abhijit, Xiao, Lanbo, Chinnaiyan, Arul M
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2024)
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Abstract 1266: Discovery and preclinical evaluation of a novel covalent inhibitor of FABP5 for cancer therapy
Chikkanna, Dinesh, Satyam, Leena Khare, Pnaigrahi, Sunil Kumar, Khairnar, Vinayak, Pothuganti, Manoj, Kaza, Lakshmi Narayan, Kalidindi, Narasimha Raju, Nataraj, Vijaya Shankar, Gatta, Aditya Kiran, Krishnamurthy, Narasimha Rao, Patil, Sandeep, Samiulla, DS, Aithal, Kiran, Ahuja, Vijay Kamal, Tiwari, Nirbhay Kumar, Charamannna, KB, Pise, Pravin, Anthony, Thomas, Nellore, Kavitha, Giri, Sanjeev, Chelur, Shekar, Samajdar, Susanta, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 4086: Preclinical evaluation of pharmacokinetics, pharmacodynamics and efficacy of the dual CD73-A2AR Inhibitors
Chikkanna, Dinesh, Narayanan, Kishore, Panigrahi, Sunil, Priyadarshini, Garima, Goyal, Megha, Mani, Jiju, Samiulla, DS, dadhania, Sagar, Aravind, AB, Daginakatte, Girish, Anthony, Thomas, Nellore, Kavitha, Samajdar, Susanta, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 1753: Targeting cancer with selective cbp/p300 bromodomain inhibitors
Jaleel, Mahaboobi, Senaiar, Ramesh S., Abbineni, Chandrasekhar, Renukappa, Girish A., Mukherjee, Subhendu, Marappan, Sivapriya, Samiulla, DS, Aravind, AB, Kumar, Naveen R., Reddy, Venkata Siva N., Babu, Asha, Srinivas, Akhila P., Yadlapalli, Prasad, Tgore, Suraj, NR, Raghavendra, Naik, Chandranath D., Giri, Sanjeev, Antony, Thomas, Nellore, Kavitha, Chelur, Shekar, Daginakatte, Girish, Ravanti, laura, Myllymäki, Mikko, Wohlfahrt, Gerd, Mattila, Elina, Karlsson, Stefan, Björkman, Mari, Riikonen, Reetta, Ikonen, Tarja, Leimu, Laura, Mälmström, Chira, Korjamo, Timo, Moilanen, Anu, Ramachandra, Murali, Samajdar, Susanta
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 1754: First in class orally bioavailable BETBRD degraders
Abbineni, Chandrasekhar, Jaleel, Mahaboobi, Mukherjee, Subhendu, Marappan, Sivapriya, Tiwari, Nirbhay Kumar, Samiulla, DS, Aravind, AB, Kumar, Naveen R, Bansal, Indu, Reddy, Raghurami B, Bandaru, NVM Rao, Srinivas, Akhila, Maben, Janith Mary, Tgore, Suraj, Kumar, Avainash, Nankar, Rakesh P., Naik, Chandranath D., Antony, Thomas, Nellore, Kavitha, Giri, Sanjeev, Daginakatte, Girish, Chelur, Shekar, Törmäkangas, Olli, Wohlfahrt, Gerd, Björkman, Mari, Mattila, Elina, Ravanti, Laura, Moilanen, Anu, Ramachandra, Murali, Samajdar, Susanta
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 6537: A novel CCR4 antagonist induces potent anti-tumor response through inhibition of Treg migration into the tumor microenvironment
Nair, Rashmi, Abbineni, Chandrasekhar, Talluri, Krishna Chaitanya, Dhudashiya, Amit A, AB, Aravind, R, Naveen Kumar, R, Ramya, Balasubramanyam, D, Obanna, Pathur, Madhaiyan, Rabin, Samiulla, DS, Daginakatte, Girish, Narayanan, Kishore, Nellore, Kavitha, Chelur, Shekar, Samajdar, Susanta, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer
He, Tongchen, Cheng, Caleb, Qiao, Yuanyuan, Cho, Hanbyul, Young, Eleanor, Mannan, Rahul, Mahapatra, Somnath, Miner, Stephanie J, Zheng, Yang, Kim, NamHoon, Zeng, Victoria Z, Wisniewski, Jasmine P, Hou, Siyu, Jackson, Bailey, Cao, Xuhong, Su, Fengyun, Wang, Rui, Chang, Yu, Kuila, Bilash, Mukherjee, Subhendu, Dukare, Sandeep, Aithal, Kiran B, D S, Samiulla, Abbineni, Chandrasekhar, Lyssiotis, Costas A, Parolia, Abhijit, Xiao, Lanbo, Chinnaiyan, Arul M
Published in bioRxiv (02.03.2024)
Published in bioRxiv (02.03.2024)
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Paper
Rational selection of structurally diverse natural product scaffolds with favorable ADME properties for drug discovery
Samiulla, D S, Vaidyanathan, V V, Arun, P C, Balan, G, Blaze, M, Bondre, S, Chandrasekhar, G, Gadakh, A, Kumar, R, Kharvi, G, Kim, H O, Kumar, S, Malikayil, J A, Moger, M, Mone, M K, Nagarjuna, P, Ogbu, C, Pendhalkar, D, Rao, A V S Raja, Rao, G Venkateshwar, Sarma, V K, Shaik, S, Sharma, G V R, Singh, S, Sreedhar, C, Sonawane, R, Timmanna, U, Hardy, L W
Published in Molecular diversity (2005)
Published in Molecular diversity (2005)
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Abstract 1144: Orally bioavailable SMARCA2 degraders with exceptional selectivity and potency
Abbineni, Chandrasekhar, Satyam, Leena Khare, Kuila, Bilash, Ettam, Ashok, Rawoof, Khaji Abdul, MR, Sreevidya, Dukare, Sandeep Vitthal, Gore, Suraj T., Nankar, Rakesh P., Ahuja, Vijay Kamal, KB, Charamanna, Goyal, Megha, Aithal, Kiran, DS, Samiulla, Mukherjee, Subhendu, Antony, Thomas, Giri, Sanjeev, Chelur, Shekar, Nellore, Kavitha, Daginakatte, Girish, Ramachandra, Murali, Samajdar, Susanta
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 3852: Combination efficacy and safety profile of an orally bioavailable small molecule agent targeting CD47/SIRPα axis
Daginakatte, Girish, Pottayil, Sasikumar, Chennakrishna, Gundala, Balasubramanian, Wesley Roy, Naremaddepalli, Sudarshan, Bhumireddy, Archana, Patil, Sandeep, Nellore, Kavitha, Chand, Priyabrata, Aithal, Kiran, Dhudashiya, Amit, DS, Samiulla, Eswarappa, Rajesh, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 3844: Anti-tumor efficacy of SMARCA degraders in pre-clinical models of cancer
Satyam, Leena Khare, Sasmal, Sanjita, Pothuganti, Manoj K., M.R., Sreevidya, Ettam, Ashokk, Nunna, Sireesha, Roshaiah, Marla, Chithaluru, Shankaraiah, Pallepati, Rangarao, Pawar, Amitkumar A., Narukulla, Leela P., Sripathi, Raghunadh A., Tgore, Suraj, Nankar, Rakesh P., KB, Charamanna, S, Nagesh Gowda, Aithal, Kiran, DS, Samiulla, Mukherjee, Subhendu, Chelur, Shekar, Nellore, Kavitha, Daginakatte, Girish, Ramachandra, Murali, Samajdar, Susanta
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 4432: A highly differentiated A2AR inhibitor for potential use in cancer therapy
Venkateshappa, Chandregowda, Narayanan, Kishore, Nair, Rashmi, AB, Aravind, Putta, Ramakishore VP, Nagaraj, Jwala, Goyal, Megha, Ahuja, Vijay Kamal, Dhudashiya, Amith A, DS, Samiulla, Daginakatte, Girish, Antony, Thomas, Nellore, Kavitha, Samajdar, Susanta, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract B172: Potent anti-tumor activity of a selective and orally bioavailable reversible covalent CDK12 inhibitor
Khare, Leena, Poddutoori, Ramulu, Mukherjee, Subhendu, DS, Samiulla, TS, Devaraja, Marappan, Sivapriya, Nayak, Shilpa, Sivakumar, Sasirekha, Kaza, Lakshmi, Tgore, Suraj, Dhudashiya, Amit, NR, Raghavendra, Gunnepalli, Bhargav, B, Aravind A, A, Amith, KB, Charamanna, Antony, Thomas, Nellore, Kavitha, Daginakatte, Girish, Chelur, Shekar, Giri, Sanjeev, Ramachandra, Murali, Samajdar, Susanta
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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Abstract 4133: ODM-203, a novel, selective and balanced FGFR and VEGFR inhibitor with strong activity on primary and metastatic tumor growth in FGFR-dependent and angiogenic cancer models
Holmström, Tim, Moilanen, Anu, Björkman, Mari, Linnanen, Tero, Wohlfahrt, Gerd, Karlsson, Stefan, Oksala, Riikka, Korjamo, Timo, Samajdar, Susanta, Rajagopalan, Srinivasan, Chelur, Shekar, Narayan, Kishore, Ramachandra, Raghuveer, Anthony, Thomas, DS, Samiulla, Ramachandra, Murali, Kallio, Pekka
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Trypsin inhibitory activity of Lawsonia inermis
Yogisha, S., Samiulla, D.S., Prashanth, D., Padmaja, R., Amit, A.
Published in Fitoterapia (01.12.2002)
Published in Fitoterapia (01.12.2002)
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Journal Article
α-Glucosidase inhibitory activity of Mangifera indica bark
Prashanth, D., Amit, A., Samiulla, D.S., Asha, M.K., Padmaja, R.
Published in Fitoterapia (01.08.2001)
Published in Fitoterapia (01.08.2001)
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