Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer's disease
Whelan, Christopher D, Mattsson, Niklas, Nagle, Michael W, Vijayaraghavan, Swetha, Hyde, Craig, Janelidze, Shorena, Stomrud, Erik, Lee, Julie, Fitz, Lori, Samad, Tarek A, Ramaswamy, Gayathri, Margolin, Richard A, Malarstig, Anders, Hansson, Oskar
Published in Acta neuropathologica communications (06.11.2019)
Published in Acta neuropathologica communications (06.11.2019)
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Journal Article
A Dysregulated Endocannabinoid-Eicosanoid Network Supports Pathogenesis in a Mouse Model of Alzheimer's Disease
Piro, Justin R., Benjamin, Daniel I., Duerr, James M., Pi, YeQing, Gonzales, Cathleen, Wood, Kathleen M., Schwartz, Joel W., Nomura, Daniel K., Samad, Tarek A.
Published in Cell reports (Cambridge) (28.06.2012)
Published in Cell reports (Cambridge) (28.06.2012)
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Journal Article
Loss of Retrograde Endocannabinoid Signaling and Reduced Adult Neurogenesis in Diacylglycerol Lipase Knock-out Mice
Gao, Ying, Vasilyev, Dmitry V, Goncalves, Maria Beatriz, Howell, Fiona V, Hobbs, Carl, Reisenberg, Melina, Shen, Ru, Zhang, Mei-Yi, Strassle, Brian W, Lu, Peimin, Mark, Lilly, Piesla, Michael J, Deng, Kangwen, Kouranova, Evguenia V, Ring, Robert H, Whiteside, Garth T, Bates, Brian, Walsh, Frank S, Williams, Gareth, Pangalos, Menelas N, Samad, Tarek A, Doherty, Patrick
Published in The Journal of neuroscience (10.02.2010)
Published in The Journal of neuroscience (10.02.2010)
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Journal Article
Inhibition of monoacylglycerol lipase terminates diazepam‐resistant status epilepticus in mice and its effects are potentiated by a ketogenic diet
Terrone, Gaetano, Pauletti, Alberto, Salamone, Alessia, Rizzi, Massimo, Villa, Bianca R., Porcu, Luca, Sheehan, Mark J., Guilmette, Edward, Butler, Christopher R., Piro, Justin R., Samad, Tarek A., Vezzani, Annamaria
Published in Epilepsia (Copenhagen) (01.01.2018)
Published in Epilepsia (Copenhagen) (01.01.2018)
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Journal Article
Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation
McAllister, Laura A, Butler, Christopher R, Mente, Scot, O’Neil, Steven V, Fonseca, Kari R, Piro, Justin R, Cianfrogna, Julie A, Foley, Timothy L, Gilbert, Adam M, Harris, Anthony R, Helal, Christopher J, Johnson, Douglas S, Montgomery, Justin I, Nason, Deane M, Noell, Stephen, Pandit, Jayvardhan, Rogers, Bruce N, Samad, Tarek A, Shaffer, Christopher L, da Silva, Rafael G, Uccello, Daniel P, Webb, Damien, Brodney, Michael A
Published in Journal of medicinal chemistry (12.04.2018)
Published in Journal of medicinal chemistry (12.04.2018)
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Journal Article
Free Water in White Matter Differentiates MCI and AD From Control Subjects
Dumont, Matthieu, Roy, Maggie, Jodoin, Pierre-Marc, Morency, Felix C., Houde, Jean-Christophe, Xie, Zhiyong, Bauer, Cici, Samad, Tarek A., Van Dijk, Koene R. A., Goodman, James A., Descoteaux, Maxime
Published in Frontiers in aging neuroscience (02.10.2019)
Published in Frontiers in aging neuroscience (02.10.2019)
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Journal Article
Dynamic changes in the microRNA expression profile reveal multiple regulatory mechanisms in the spinal nerve ligation model of neuropathic pain
von Schack, David, Agostino, Michael J, Murray, B Stuart, Li, Yizheng, Reddy, Padmalatha S, Chen, Jin, Choe, Sung E, Strassle, Brian W, Li, Christine, Bates, Brian, Zhang, Lynn, Hu, Huijuan, Kotnis, Smita, Bingham, Brendan, Liu, Wei, Whiteside, Garth T, Samad, Tarek A, Kennedy, Jeffrey D, Ajit, Seena K
Published in PloS one (14.03.2011)
Published in PloS one (14.03.2011)
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Journal Article
Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system
Chanda, Pranab K, Gao, Ying, Mark, Lilly, Btesh, Joan, Strassle, Brian W, Lu, Peimin, Piesla, Michael J, Zhang, Mei-Yi, Bingham, Brendan, Uveges, Albert, Kowal, Dianne, Garbe, David, Kouranova, Evguenia V, Ring, Robert H, Bates, Brian, Pangalos, Menelas N, Kennedy, Jeffrey D, Whiteside, Garth T, Samad, Tarek A
Published in Molecular pharmacology (01.12.2010)
Published in Molecular pharmacology (01.12.2010)
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Journal Article
Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase
Butler, Christopher R., Beck, Elizabeth M., Harris, Anthony, Huang, Zhen, McAllister, Laura A., am Ende, Christopher W., Fennell, Kimberly, Foley, Timothy L., Fonseca, Kari, Hawrylik, Steven J., Johnson, Douglas S., Knafels, John D., Mente, Scot, Noell, G. Stephen, Pandit, Jayvardhan, Phillips, Tracy B., Piro, Justin R., Rogers, Bruce N., Samad, Tarek A., Wang, Jane, Wan, Shuangyi, Brodney, Michael A.
Published in Journal of medicinal chemistry (14.12.2017)
Published in Journal of medicinal chemistry (14.12.2017)
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Journal Article
Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury
Piro, Justin R, Suidan, Georgette L, Quan, Jie, Pi, YeQing, O'Neill, Sharon M, Ilardi, Marissa, Pozdnyakov, Nikolay, Lanz, Thomas A, Xi, Hualin, Bell, Robert D, Samad, Tarek A
Published in Journal of neuroinflammation (14.05.2018)
Published in Journal of neuroinflammation (14.05.2018)
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Journal Article
Prostaglandin E2 Receptor EP4 Contributes to Inflammatory Pain Hypersensitivity
Lin, Chung-Ren, Amaya, Fumimasa, Barrett, Lee, Wang, Haibin, Takada, Junji, Samad, Tarek A, Woolf, Clifford J
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)
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Journal Article
Depression-like phenotype following chronic CB1 receptor antagonism
Beyer, Chad E, Dwyer, Jason M, Piesla, Michael J, Platt, Brian J, Shen, Ru, Rahman, Zia, Chan, Karen, Manners, Melissa T, Samad, Tarek A, Kennedy, Jeffrey D, Bingham, Brendan, Whiteside, Garth T
Published in Neurobiology of disease (01.08.2010)
Published in Neurobiology of disease (01.08.2010)
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Journal Article
The BMP coreceptor RGMb promotes while the endogenous BMP antagonist noggin reduces neurite outgrowth and peripheral nerve regeneration by modulating BMP signaling
Ma, Chi H E, Brenner, Gary J, Omura, Takao, Samad, Omar A, Costigan, Michael, Inquimbert, Perrine, Niederkofler, Vera, Salie, Rishard, Sun, Chia Chi, Lin, Herbert Y, Arber, Silvia, Coppola, Giovanni, Woolf, Clifford J, Samad, Tarek A
Published in The Journal of neuroscience (14.12.2011)
Published in The Journal of neuroscience (14.12.2011)
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Journal Article
Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages
Xia, Yin, Cortez-Retamozo, Virna, Niederkofler, Vera, Salie, Rishard, Chen, Shanzhuo, Samad, Tarek A, Hong, Charles C, Arber, Silvia, Vyas, Jatin M, Weissleder, Ralph, Pittet, Mikael J, Lin, Herbert Y
Published in The Journal of immunology (1950) (01.02.2011)
Published in The Journal of immunology (1950) (01.02.2011)
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Journal Article
Repulsive Guidance Molecule (RGMa), a DRAGON Homologue, Is a Bone Morphogenetic Protein Co-receptor
Babitt, Jodie L, Zhang, Ying, Samad, Tarek A, Xia, Yin, Tang, Jie, Campagna, Jason A, Schneyer, Alan L, Woolf, Clifford J, Lin, Herbert Y
Published in The Journal of biological chemistry (19.08.2005)
Published in The Journal of biological chemistry (19.08.2005)
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Journal Article
Prostanoids and pain: unraveling mechanisms and revealing therapeutic targets
Samad, Tarek A, Sapirstein, Adam, Woolf, Clifford J
Published in Trends in Molecular Medicine (01.08.2002)
Published in Trends in Molecular Medicine (01.08.2002)
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Book Review
Journal Article
DRAGON, a Bone Morphogenetic Protein Co-receptor
Samad, Tarek A., Rebbapragada, Anuradha, Bell, Esther, Zhang, Ying, Sidis, Yisrael, Jeong, Sung-Jin, Campagna, Jason A., Perusini, Stephen, Fabrizio, David A., Schneyer, Alan L., Lin, Herbert Y., Brivanlou, Ali H., Attisano, Liliana, Woolf, Clifford J.
Published in The Journal of biological chemistry (08.04.2005)
Published in The Journal of biological chemistry (08.04.2005)
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Journal Article
Absence of dopamine D2 receptors unmasks an inhibitory control over the brain circuitries activated by cocaine
Welter, Marc, Vallone, Daniela, Samad, Tarek A, Meziane, Hamid, Usiello, Alessandro, Borrelli, Emiliana
Published in Proceedings of the National Academy of Sciences - PNAS (17.04.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (17.04.2007)
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Journal Article