Cellular senescence mediates fibrotic pulmonary disease
Schafer, Marissa J, White, Thomas A, Iijima, Koji, Haak, Andrew J, Ligresti, Giovanni, Atkinson, Elizabeth J, Oberg, Ann L, Birch, Jodie, Salmonowicz, Hanna, Zhu, Yi, Mazula, Daniel L, Brooks, Robert W, Fuhrmann-Stroissnigg, Heike, Pirtskhalava, Tamar, Prakash, Y S, Tchkonia, Tamara, Robbins, Paul D, Aubry, Marie Christine, Passos, João F, Kirkland, James L, Tschumperlin, Daniel J, Kita, Hirohito, LeBrasseur, Nathan K
Published in Nature communications (23.02.2017)
Published in Nature communications (23.02.2017)
Get full text
Journal Article
Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice
Ogrodnik, Mikolaj, Evans, Shane A., Fielder, Edward, Victorelli, Stella, Kruger, Patrick, Salmonowicz, Hanna, Weigand, Bettina M., Patel, Ayush D., Pirtskhalava, Tamar, Inman, Christine L., Johnson, Kurt O., Dickinson, Stephanie L., Rocha, Azucena, Schafer, Marissa J., Zhu, Yi, Allison, David B., Zglinicki, Thomas, LeBrasseur, Nathan K., Tchkonia, Tamar, Neretti, Nicola, Passos, João F., Kirkland, James L., Jurk, Diana
Published in Aging cell (01.02.2021)
Published in Aging cell (01.02.2021)
Get full text
Journal Article
Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan
Piper, Matthew D.W., Soultoukis, George A., Blanc, Eric, Mesaros, Andrea, Herbert, Samantha L., Juricic, Paula, He, Xiaoli, Atanassov, Ilian, Salmonowicz, Hanna, Yang, Mingyao, Simpson, Stephen J., Ribeiro, Carlos, Partridge, Linda
Published in Cell metabolism (07.03.2017)
Published in Cell metabolism (07.03.2017)
Get full text
Journal Article
Dynamic JUNQ inclusion bodies are asymmetrically inherited in mammalian cell lines through the asymmetric partitioning of vimentin
Ogrodnik, Mikolaj, Salmonowicz, Hanna, Brown, Rachel, Turkowska, Joanna, Sredniawa, Wladyslaw, Pattabiraman, Sundararaghavan, Amen, Triana, Abraham, Ayelet-chen, Eichler, Noam, Lyakhovetsky, Roman, Kaganovich, Daniel
Published in Proceedings of the National Academy of Sciences - PNAS (03.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (03.06.2014)
Get full text
Journal Article
Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
Kelly, George, Kataura, Tetsushi, Panek, Johan, Ma, Gailing, Salmonowicz, Hanna, Davis, Ashley, Kendall, Hannah, Brookes, Charlotte, Ayine-Tora, Daniel Moscoh, Banks, Peter, Nelson, Glyn, Dobby, Laura, Pitrez, Patricia R., Booth, Laura, Costello, Lydia, Richardson, Gavin D., Lovat, Penny, Przyborski, Stefan, Ferreira, Lino, Greaves, Laura, Szczepanowska, Karolina, von Zglinicki, Thomas, Miwa, Satomi, Brown, Max, Flagler, Michael, Oblong, John E., Bascom, Charles C., Carroll, Bernadette, Reynisson, Jóhannes, Korolchuk, Viktor I.
Published in Developmental cell (05.08.2024)
Published in Developmental cell (05.08.2024)
Get full text
Journal Article
Activation of transcription enforces the formation of distinct nuclear bodies in zebrafish embryos
Heyn, Patricia, Salmonowicz, Hanna, Rodenfels, Jonathan, Neugebauer, Karla M.
Published in RNA biology (03.06.2017)
Published in RNA biology (03.06.2017)
Get full text
Journal Article
Mitochondria and cellular senescence: Implications for musculoskeletal ageing
Habiballa, Leena, Salmonowicz, Hanna, Passos, João F.
Published in Free radical biology & medicine (20.02.2019)
Published in Free radical biology & medicine (20.02.2019)
Get full text
Journal Article
Cytoplasmic DNA: sources, sensing, and role in aging and disease
Miller, Karl N., Victorelli, Stella G., Salmonowicz, Hanna, Dasgupta, Nirmalya, Liu, Tianhui, Passos, João F., Adams, Peter D.
Published in Cell (28.10.2021)
Published in Cell (28.10.2021)
Get full text
Journal Article
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence
Anderson, Rhys, Lagnado, Anthony, Maggiorani, Damien, Walaszczyk, Anna, Dookun, Emily, Chapman, James, Birch, Jodie, Salmonowicz, Hanna, Ogrodnik, Mikolaj, Jurk, Diana, Proctor, Carole, Correia‐Melo, Clara, Victorelli, Stella, Fielder, Edward, Berlinguer‐Palmini, Rolando, Owens, Andrew, Greaves, Laura C, Kolsky, Kathy L, Parini, Angelo, Douin‐Echinard, Victorine, LeBrasseur, Nathan K, Arthur, Helen M, Tual‐Chalot, Simon, Schafer, Marissa J, Roos, Carolyn M, Miller, Jordan D, Robertson, Neil, Mann, Jelena, Adams, Peter D, Tchkonia, Tamara, Kirkland, James L, Mialet‐Perez, Jeanne, Richardson, Gavin D, Passos, João F
Published in The EMBO journal (01.03.2019)
Published in The EMBO journal (01.03.2019)
Get full text
Journal Article
Apoptotic stress causes mtDNA release during senescence and drives the SASP
Victorelli, Stella, Salmonowicz, Hanna, Chapman, James, Martini, Helene, Vizioli, Maria Grazia, Riley, Joel S, Cloix, Catherine, Hall-Younger, Ella, Machado Espindola-Netto, Jair, Jurk, Diana, Lagnado, Anthony B, Sales Gomez, Lilian, Farr, Joshua N, Saul, Dominik, Reed, Rebecca, Kelly, George, Eppard, Madeline, Greaves, Laura C, Dou, Zhixun, Pirius, Nicholas, Szczepanowska, Karolina, Porritt, Rebecca A, Huang, Huijie, Huang, Timothy Y, Mann, Derek A, Masuda, Claudio Akio, Khosla, Sundeep, Dai, Haiming, Kaufmann, Scott H, Zacharioudakis, Emmanouil, Gavathiotis, Evripidis, LeBrasseur, Nathan K, Lei, Xue, Sainz, Alva G, Korolchuk, Viktor I, Adams, Peter D, Shadel, Gerald S, Tait, Stephen W G, Passos, João F
Published in Nature (London) (19.10.2023)
Published in Nature (London) (19.10.2023)
Get full text
Journal Article
Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner
Lagnado, Anthony, Leslie, Jack, Ruchaud‐Sparagano, Marie‐Helene, Victorelli, Stella, Hirsova, Petra, Ogrodnik, Mikolaj, Collins, Amy L, Vizioli, Maria Grazia, Habiballa, Leena, Saretzki, Gabriele, Evans, Shane A, Salmonowicz, Hanna, Hruby, Adam, Geh, Daniel, Pavelko, Kevin D, Dolan, David, Reeves, Helen L, Grellscheid, Sushma, Wilson, Colin H, Pandanaboyana, Sanjay, Doolittle, Madison, Zglinicki, Thomas, Oakley, Fiona, Gallage, Suchira, Wilson, Caroline L, Birch, Jodie, Carroll, Bernadette, Chapman, James, Heikenwalder, Mathias, Neretti, Nicola, Khosla, Sundeep, Masuda, Claudio Akio, Tchkonia, Tamar, Kirkland, James L, Jurk, Diana, Mann, Derek A, Passos, João F
Published in The EMBO journal (03.05.2021)
Published in The EMBO journal (03.05.2021)
Get full text
Journal Article
The Pet127 protein is a mitochondrial 5'-to-3' exoribonuclease from the PD-(D/E)XK superfamily involved in RNA maturation and intron degradation in yeasts
Łabędzka-Dmoch, Karolina, Rażew, Michal, Gapińska, Marta, Piątkowski, Jakub, Kolondra, Adam, Salmonowicz, Hanna, Wenda, Joanna M, Nowotny, Marcin, Golik, Paweł
Published in RNA (Cambridge) (01.05.2022)
Published in RNA (Cambridge) (01.05.2022)
Get full text
Journal Article
Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP
Victorelli, Stella, Salmonowicz, Hanna, Chapman, James, Martini, Helene, Vizioli, Maria Grazia, Riley, Joel S, Cloix, Catherine, Hall-Younger, Ella, Machado Espindola-Netto, Jair, Jurk, Diana, Lagnado, Anthony B, Sales Gomez, Lilian, Farr, Joshua N, Saul, Dominik, Reed, Rebecca, Kelly, George, Eppard, Madeline, Greaves, Laura C, Dou, Zhixun, Pirius, Nicholas, Szczepanowska, Karolina, Porritt, Rebecca A, Huang, Huijie, Huang, Timothy Y, Mann, Derek A, Masuda, Claudio Akio, Khosla, Sundeep, Dai, Haiming, Kaufmann, Scott H, Zacharioudakis, Emmanouil, Gavathiotis, Evripidis, LeBrasseur, Nathan K, Lei, Xue, Sainz, Alva G, Korolchuk, Viktor I, Adams, Peter D, Shadel, Gerald S, Tait, Stephen W G, Passos, João F
Published in Nature (London) (01.01.2024)
Published in Nature (London) (01.01.2024)
Get full text
Journal Article
Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan
Piper, Matthew D.W., Soultoukis, George A., Blanc, Eric, Mesaros, Andrea, Herbert, Samantha L., Juricic, Paula, He, Xiaoli, Atanassov, Ilian, Salmonowicz, Hanna, Yang, Mingyao, Simpson, Stephen J., Ribeiro, Carlos, Partridge, Linda
Published in Cell metabolism (02.05.2017)
Published in Cell metabolism (02.05.2017)
Get full text
Journal Article
Length-independent telomere damage drives cardiomyocyte senescence
Anderson, Rhys, Lagnado, Anthony, Maggiorani, Damien, Walaszczyk, Anna, Dookun, Emily, Chapman, James, Birch, Jodie, Salmonowicz, Hanna, Ogrodnik, Mikolaj, Jurk, Diana, Proctor, Carole, Correia-Melo, Clara, Victorelli, Stella, Fielder, Edward, Berlinguer-Palmini, Rolando, Owens, W Andrew, Greaves, Laura, Kolsky, Kathy, Parini, Angelo, Douin-Echinard, Victorine, Lebrasseur, Nathan, Arthur, Helen, Simon Tual-Chalot, Schafer, Marissa, Roos, Carolyn, Miller, Jordan, Robertson, Neil, Mann, Jelena, Adams, Peter D, Tchkonia, Tamara, Kirkland, Jams L, Mialet-Perez, Jeanne, Richardson, Gavin David, Passos, Joao F
Published in bioRxiv (17.08.2018)
Published in bioRxiv (17.08.2018)
Get full text
Paper