ERK is a Pivotal Player of Chemo-Immune-Resistance in Cancer
Salaroglio, Iris C, Mungo, Eleonora, Gazzano, Elena, Kopecka, Joanna, Riganti, Chiara
Published in International journal of molecular sciences (21.05.2019)
Published in International journal of molecular sciences (21.05.2019)
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Journal Article
PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy
Salaroglio, Iris C, Panada, Elisa, Moiso, Enrico, Buondonno, Ilaria, Provero, Paolo, Rubinstein, Menachem, Kopecka, Joanna, Riganti, Chiara
Published in Molecular cancer (12.05.2017)
Published in Molecular cancer (12.05.2017)
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Journal Article
Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors
Gazzano, Elena, Rolando, Barbara, Chegaev, Konstantin, Salaroglio, Iris C., Kopecka, Joanna, Pedrini, Isabella, Saponara, Simona, Sorge, Matteo, Buondonno, Ilaria, Stella, Barbara, Marengo, Alessandro, Valoti, Massimo, Brancaccio, Mara, Fruttero, Roberta, Gasco, Alberto, Arpicco, Silvia, Riganti, Chiara
Published in Journal of controlled release (28.01.2018)
Published in Journal of controlled release (28.01.2018)
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Journal Article
Mitochondria-Targeted Doxorubicin: A New Therapeutic Strategy against Doxorubicin-Resistant Osteosarcoma
Buondonno, Ilaria, Gazzano, Elena, Jean, Sae Rin, Audrito, Valentina, Kopecka, Joanna, Fanelli, Marilù, Salaroglio, Iris C, Costamagna, Costanzo, Roato, Ilaria, Mungo, Eleonora, Hattinger, Claudia M, Deaglio, Silvia, Kelley, Shana O, Serra, Massimo, Riganti, Chiara
Published in Molecular cancer therapeutics (01.11.2016)
Published in Molecular cancer therapeutics (01.11.2016)
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Journal Article
A novel combinatory treatment against a CDDP-resistant non-small cell lung cancer based on a Ruthenium(II)-cyclopentadienyl compound
Salaroglio, Iris C., Stefanova, Denitsa, Teixeira, Ricardo G., Oliveira, Nuno F.B., Ahmed, Amer, Fusi, Fabio, Tzankova, Virginia, Yordanov, Yordan, Machuqueiro, Miguel, Saponara, Simona, Valente, Andreia, Riganti, Chiara
Published in Pharmacological research (01.10.2024)
Published in Pharmacological research (01.10.2024)
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Journal Article
Potential Diagnostic and Prognostic Role of Microenvironment in Malignant Pleural Mesothelioma
Salaroglio, Iris C., Kopecka, Joanna, Napoli, Francesca, Pradotto, Monica, Maletta, Francesca, Costardi, Lorena, Gagliasso, Matteo, Milosevic, Vladan, Ananthanarayanan, Preeta, Bironzo, Paolo, Tabbò, Fabrizio, Cartia, Carlotta F., Passone, Erika, Comunanza, Valentina, Ardissone, Francesco, Ruffini, Enrico, Bussolino, Federico, Righi, Luisella, Novello, Silvia, Di Maio, Massimo, Papotti, Mauro, Scagliotti, Giorgio V., Riganti, Chiara
Published in Journal of thoracic oncology (01.08.2019)
Published in Journal of thoracic oncology (01.08.2019)
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Journal Article
Mitochondrial ROS drive resistance to chemotherapy and immune-killing in hypoxic non-small cell lung cancer
Salaroglio, Iris C., Belisario, Dimas Carolina, Akman, Muhlis, La Vecchia, Sofia, Godel, Martina, Anobile, Dario Pasquale, Ortone, Giacomo, Digiovanni, Sabrina, Fontana, Simona, Costamagna, Costanzo, Rubinstein, Menachem, Kopecka, Joanna, Riganti, Chiara
Published in Journal of experimental & clinical cancer research (11.08.2022)
Published in Journal of experimental & clinical cancer research (11.08.2022)
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Journal Article
Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer
Salaroglio, Iris C, Gazzano, Elena, Abdullrahman, Ahmad, Mungo, Eleonora, Castella, Barbara, Abd-Elrahman, Gamal Eldein Fathy Abd-Ellatef, Massaia, Massimo, Donadelli, Massimo, Rubinstein, Menachem, Riganti, Chiara, Kopecka, Joanna
Published in Journal of experimental & clinical cancer research (27.11.2018)
Published in Journal of experimental & clinical cancer research (27.11.2018)
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Journal Article
Hypoxia as a driver of resistance to immunotherapy
Kopecka, Joanna, Salaroglio, Iris C., Perez-Ruiz, Elizabeth, Sarmento-Ribeiro, Ana Bela, Saponara, Simona, De Las Rivas, Javier, Riganti, Chiara
Published in Drug resistance updates (01.12.2021)
Published in Drug resistance updates (01.12.2021)
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Journal Article
Mitochondrial metabolism: Inducer or therapeutic target in tumor immune-resistance?
Kopecka, Joanna, Gazzano, Elena, Castella, Barbara, Salaroglio, Iris C., Mungo, Eleonora, Massaia, Massimo, Riganti, Chiara
Published in Seminars in cell & developmental biology (01.02.2020)
Published in Seminars in cell & developmental biology (01.02.2020)
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Journal Article
Carbonic Anhydrase XII Inhibitors Overcome P-Glycoprotein-Mediated Resistance to Temozolomide in Glioblastoma
Salaroglio, Iris C, Mujumdar, Prashant, Annovazzi, Laura, Kopecka, Joanna, Mellai, Marta, Schiffer, Davide, Poulsen, Sally-Ann, Riganti, Chiara
Published in Molecular cancer therapeutics (01.12.2018)
Published in Molecular cancer therapeutics (01.12.2018)
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Journal Article
Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P‑Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells
Riganti, Chiara, Contino, Marialessandra, Guglielmo, Stefano, Perrone, Maria G, Salaroglio, Iris C, Milosevic, Vladan, Giampietro, Roberta, Leonetti, Francesco, Rolando, Barbara, Lazzarato, Loretta, Colabufo, Nicola A, Fruttero, Roberta
Published in Journal of medicinal chemistry (24.01.2019)
Published in Journal of medicinal chemistry (24.01.2019)
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Journal Article
Fighting Multidrug Resistance with Ruthenium–Cyclopentadienyl Compounds: Unveiling the Mechanism of P‑gp Inhibition
Teixeira, Ricardo G., Salaroglio, Iris C., Oliveira, Nuno F. B., Sequeira, João G. N., Fontrodona, Xavier, Romero, Isabel, Machuqueiro, Miguel, Tomaz, Ana Isabel, Garcia, M. Helena, Riganti, Chiara, Valente, Andreia
Published in Journal of medicinal chemistry (26.10.2023)
Published in Journal of medicinal chemistry (26.10.2023)
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Journal Article
Autocrine 17-β-estradiol/estrogen receptor-α loop determines the response to immune-checkpoint inhibitors in non-small cell lung cancer
Anobile, Dario P, Salaroglio, Iris C, Tabbò, Fabrizio, La Vecchia, Sofia, Akman, Muhlis, Napoli, Francesca, Bungaro, Maristella, Benso, Federica, Aldieri, Elisabetta, Bironzo, Paolo, Kopecka, Joanna, Passiglia, Francesco, Righi, Luisella, Novello, Silvia, Scagliotti, Giorgio V, Riganti, Chiara
Published in Clinical cancer research (02.10.2023)
Published in Clinical cancer research (02.10.2023)
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Journal Article
Wnt/IL‐1β/IL‐8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5
Milosevic, Vladan, Kopecka, Joanna, Salaroglio, Iris C., Libener, Roberta, Napoli, Francesca, Izzo, Stefania, Orecchia, Sara, Ananthanarayanan, Preeta, Bironzo, Paolo, Grosso, Federica, Tabbò, Fabrizio, Comunanza, Valentina, Alexa‐Stratulat, Teodora, Bussolino, Federico, Righi, Luisella, Novello, Silvia, Scagliotti, Giorgio V., Riganti, Chiara
Published in International journal of cancer (01.01.2020)
Published in International journal of cancer (01.01.2020)
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Journal Article
P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors
Kopecka, Joanna, Rankin, Gregory M, Salaroglio, Iris C, Poulsen, Sally-Ann, Riganti, Chiara
Published in Oncotarget (27.12.2016)
Published in Oncotarget (27.12.2016)
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Journal Article
Increasing intratumor C/EBP-[beta] LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer
Salaroglio, Iris C, Gazzano, Elena, Abdullrahman, Ahmad, Mungo, Eleonora, Castella, Barbara, Abd-elrahman, Gamal Eldein Fathy Abd-ellatef, Massaia, Massimo, Donadelli, Massimo, Rubinstein, Menachem, Riganti, Chiara, Kopecka, Joanna
Published in Journal of experimental & clinical cancer research (27.11.2018)
Published in Journal of experimental & clinical cancer research (27.11.2018)
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Journal Article
The Cross-Talk between Canonical and Non-Canonical Wnt-Dependent Pathways Regulates P-Glycoprotein Expression in Human Blood–Brain Barrier Cells
Pinzón-Daza, Martha L, Salaroglio, Iris C, Kopecka, Joanna, Garzòn, Ruth, Couraud, Pierre-Olivier, Ghigo, Dario, Riganti, Chiara
Published in Journal of cerebral blood flow and metabolism (01.08.2014)
Published in Journal of cerebral blood flow and metabolism (01.08.2014)
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Journal Article
Loss of C/EBP-β LIP drives cisplatin resistance in malignant pleural mesothelioma
Kopecka, Joanna, Salaroglio, Iris C., Righi, Luisella, Libener, Roberta, Orecchia, Sara, Grosso, Federica, Milosevic, Vladan, Ananthanarayanan, Preeta, Ricci, Luisa, Capelletto, Enrica, Pradotto, Monica, Napoli, Francesca, Di Maio, Massimo, Novello, Silvia, Rubinstein, Menachem, Scagliotti, Giorgio V., Riganti, Chiara
Published in Lung cancer (Amsterdam, Netherlands) (01.06.2018)
Published in Lung cancer (Amsterdam, Netherlands) (01.06.2018)
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Journal Article
Temozolomide down-regulates P-glycoprotein in human blood–brain barrier cells by disrupting Wnt3 signaling
Riganti, Chiara, Salaroglio, Iris C, Pinzòn-Daza, Martha L, Caldera, Valentina, Campia, Ivana, Kopecka, Joanna, Mellai, Marta, Annovazzi, Laura, Couraud, Pierre-Olivier, Bosia, Amalia, Ghigo, Dario, Schiffer, Davide
Published in Cellular and molecular life sciences : CMLS (01.02.2014)
Published in Cellular and molecular life sciences : CMLS (01.02.2014)
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