Targeting Myeloid Differentiation Primary Response Protein 88 (MyD88) and Galectin-3 to Develop Broad-Spectrum Host-Mediated Therapeutics against SARS-CoV-2
Saikh, Kamal U, Anam, Khairul, Sultana, Halima, Ahmed, Rakin, Kumar, Simran, Srinivasan, Sanjay, Ahmed, Hafiz
Published in International journal of molecular sciences (01.08.2024)
Published in International journal of molecular sciences (01.08.2024)
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Journal Article
Activation of MyD88 signaling upon staphylococcal enterotoxin binding to MHC class II molecules
Kissner, Teri L, Ruthel, Gordon, Alam, Shahabuddin, Ulrich, Robert G, Fernandez, Stefan, Saikh, Kamal U
Published in PloS one (20.01.2011)
Published in PloS one (20.01.2011)
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Protective Immunization against Inhalational Anthrax: A Comparison of Minimally Invasive Delivery Platforms
Mikszta, John A., Sullivan, Vincent J., Dean, Cheryl, Waterston, Andrea M., Alarcon, Jason B., Dekker, John P., Brittingham, John M., Huang, Juan, Hwang, C. Robin, Ferriter, Matthew, Jiang, Ge, Mar, Kevin, Saikh, Kamal U., Stiles, Bradley G., Roy, Chad J., Ulrich, Robert G., Harvey, Noel G.
Published in The Journal of infectious diseases (15.01.2005)
Published in The Journal of infectious diseases (15.01.2005)
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Therapeutic inhibition of pro-inflammatory signaling and toxicity to staphylococcal enterotoxin B by a synthetic dimeric BB-loop mimetic of MyD88
Kissner, Teri L, Ruthel, Gordon, Alam, Shahabuddin, Mann, Enrique, Ajami, Dariush, Rebek, Mitra, Larkin, Eileen, Fernandez, Stefan, Ulrich, Robert G, Ping, Sun, Waugh, David S, Rebek, Jr, Julius, Saikh, Kamal U
Published in PloS one (27.07.2012)
Published in PloS one (27.07.2012)
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Journal Article
An increase in p62/NBR1 levels in melioidosis patients of Sri Lanka exhibit a characteristic of potential host biomarker
Saikh, Kamal U, Ranji, Cyra M, Ulrich, Robert G, Corea, Enoka, De Silva, Aruna Dharshan, Natesan, Mohan
Published in Journal of medical microbiology (01.10.2020)
Published in Journal of medical microbiology (01.10.2020)
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Toll-Like Receptor and Cytokine Expression Patterns of CD56+ T Cells Are Similar to Natural Killer Cells in Response to Infection with Venezuelan Equine Encephalitis Virus Replicons
Saikh, Kamal U., Lee, John S., Kissner, Teri L., Dyas, Beverly, Ulrich, Robert G.
Published in The Journal of infectious diseases (15.11.2003)
Published in The Journal of infectious diseases (15.11.2003)
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Journal Article
Small Molecule Analogues of the parasitic worm product ES-62 interact with the TIR domain of MyD88 to inhibit pro-inflammatory signalling
Suckling, Colin J., Alam, Shahabuddin, Olson, Mark A., Saikh, Kamal U., Harnett, Margaret M., Harnett, William
Published in Scientific reports (01.02.2018)
Published in Scientific reports (01.02.2018)
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Journal Article
Human Cytolytic T Cell Recognition of Yersinia pestis Virulence Proteins That Target Innate Immune Responses
Saikh, Kamal U. , Kissner, Teri L. , Dyas, Beverly , Tropea, Joseph E. , Waugh, David S. , Ulrich, Robert G.
Published in The Journal of infectious diseases (15.12.2006)
Published in The Journal of infectious diseases (15.12.2006)
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Journal Article
Author Correction: Discovery of small molecule inhibitors of MyD88-dependent signaling pathways using a computational screen
Olson, Mark A., Lee, Michael S., Kissner, Teri L., Alam, Shahabuddin, Waugh, David S., Saikh, Kamal U.
Published in Scientific reports (19.11.2018)
Published in Scientific reports (19.11.2018)
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Journal Article
Rational design of peptide derivatives for inhibition of MyD88‐mediated toll‐like receptor signaling in human peripheral blood mononuclear cells and epithelial cells exposed to Francisella tularensis
Ryan, Daniel A., Degardin, Melissa, Alam, Shahabuddin, Kissner, Teri L., Hale, Martha, Cameron, Michael D., Rebek, Mitra, Ajami, Dariush, Saikh, Kamal U., Rebek, Julius
Published in Chemical biology & drug design (01.12.2017)
Published in Chemical biology & drug design (01.12.2017)
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A Small Molecule That Mimics the BB-loop in the Toll Interleukin-1 (IL-1) Receptor Domain of MyD88 Attenuates Staphylococcal Enterotoxin B-induced Pro-inflammatory Cytokine Production and Toxicity in Mice
Kissner, Teri L., Moisan, Lionel, Mann, Enrique, Alam, Shahabuddin, Ruthel, Gordon, Ulrich, Robert G., Rebek, Mitra, Rebek, Julius, Saikh, Kamal U.
Published in The Journal of biological chemistry (09.09.2011)
Published in The Journal of biological chemistry (09.09.2011)
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An increase in intracellular p62/NBR1 and persistence of Burkholderia mallei and B. pseudomallei in infected mice linked to autophagy deficiency
Saikh, Kamal U., Dankmeyer, Jennifer L., Zeng, Xiankun, Ulrich, Robert G., Amemiya, Kei
Published in Immunity, Inflammation and Disease (01.03.2019)
Published in Immunity, Inflammation and Disease (01.03.2019)
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Structure-Based Design and Synthesis of a Small Molecule that Exhibits Anti-inflammatory Activity by Inhibition of MyD88-mediated Signaling to Bacterial Toxin Exposure
Alam, Shahabuddin, Javor, Sacha, Degardin, Melissa, Ajami, Dariush, Rebek, Mitra, Kissner, Teri L., Waag, David M., Rebek Jr, Julius, Saikh, Kamal U.
Published in Chemical biology & drug design (01.08.2015)
Published in Chemical biology & drug design (01.08.2015)
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