Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase
Varghese, Joseph N, Smith, Paul W, Sollis, Steven L, Blick, Tony J, Sahasrabudhe, Anjali, McKimm-Breschkin, Jennifer L, Colman, Peter M
Published in Structure (London) (15.06.1998)
Published in Structure (London) (15.06.1998)
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Mutations in a Conserved Residue in the Influenza Virus Neuraminidase Active Site Decreases Sensitivity to Neu5Ac2en-Derived Inhibitors
McKimm-Breschkin, J L, Sahasrabudhe, A, Blick, T J, McDonald, M, Colman, P M, Hart, G J, Bethell, R C, Varghese, J N
Published in Journal of Virology (01.03.1998)
Published in Journal of Virology (01.03.1998)
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Journal Article
Structural Evidence for a Second Sialic Acid Binding Site in Avian Influenza Virus Neuraminidases
Varghese, J N, Colman, P M, van Donkelaar, A, Blick, T J, Sahasrabudhe, A, McKimm-Breschkin, J L
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.1997)
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The Interaction of Neuraminidase and Hemagglutinin Mutations in Influenza Virus in Resistance to 4-Guanidino-Neu5Ac2en
Blick, Tony J., Sahasrabudhe, Anjali, McDonald, Mandy, Owens, Ian J., Morley, Peter J., Fenton, Robert J., McKimm-Breschkin, Jennifer L.
Published in Virology (New York, N.Y.) (20.06.1998)
Published in Virology (New York, N.Y.) (20.06.1998)
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Journal Article
Mutations conferring zanamivir resistance in human influenza virus N2 neuraminidases compromise virus fitness and are not stably maintained in vitro
Zürcher, Thomas, Yates, Phillip J., Daly, Janet, Sahasrabudhe, Anjali, Walters, Matthew, Dash, Laura, Tisdale, Margaret, McKimm-Breschkin, Jennifer L.
Published in Journal of antimicrobial chemotherapy (01.10.2006)
Published in Journal of antimicrobial chemotherapy (01.10.2006)
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Generation and Characterization of an Influenza Virus Neuraminidase Variant with Decreased Sensitivity to the Neuraminidase-Specific Inhibitor 4-Guanidino-Neu5Ac2en
BLICK, TONY J., TIONG, TAK, SAHASRABUDHE, ANJALI, VARGHESE, JOSEPH N., COLMAN, PETER M., HART, GRAHAM J., BETHELL, RICHARD C., McKIMM-BRESCHKIN, JENNIFER L.
Published in Virology (New York, N.Y.) (20.12.1995)
Published in Virology (New York, N.Y.) (20.12.1995)
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Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4-guanidino-Neu5Ac2en
McKimm-Breschkin, J L, Blick, T J, Sahasrabudhe, A, Tiong, T, Marshall, D, Hart, G J, Bethell, R C, Penn, C R
Published in Antimicrobial Agents and Chemotherapy (01.01.1996)
Published in Antimicrobial Agents and Chemotherapy (01.01.1996)
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Journal Article
Substrate, Inhibitor, or Antibody Stabilizes the Glu 119 Gly Mutant Influenza Virus Neuraminidase
Sahasrabudhe, Anjali, Lawrence, Lynne, Epa, V.Chandana, Varghese, Joseph N., Colman, Peter M., McKimm-Breschkin, Jennifer L.
Published in Virology (New York, N.Y.) (20.07.1998)
Published in Virology (New York, N.Y.) (20.07.1998)
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Journal Article
Mechanisms of resistance of influenza virus to neuraminidase inhibitors
McKimm-Breschkin, Jennifer, Sahasrabudhe, Anjali, Blick, Tony, McDonald, Mandy
Published in International Congress series (01.10.2001)
Published in International Congress series (01.10.2001)
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Journal Article
Production of Recombinant Human Bile Salt Stimulated Lipase and Its Variant inPichia pastoris
Sahasrabudhe, Anjali V., Solapure, Suresh M., Khurana, Rajeev, Suryanarayan, Vepa, Ravishankar, Sudha, deSousa, Sunita M., Das, Goutam
Published in Protein expression and purification (01.12.1998)
Published in Protein expression and purification (01.12.1998)
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