SIRT4 Coordinates the Balance between Lipid Synthesis and Catabolism by Repressing Malonyl CoA Decarboxylase
Laurent, Gaëlle, German, Natalie J., Saha, Asish K., de Boer, Vincent C.J., Davies, Michael, Koves, Timothy R., Dephoure, Noah, Fischer, Frank, Boanca, Gina, Vaitheesvaran, Bhavapriya, Lovitch, Scott B., Sharpe, Arlene H., Kurland, Irwin J., Steegborn, Clemens, Gygi, Steven P., Muoio, Deborah M., Ruderman, Neil B., Haigis, Marcia C.
Published in Molecular cell (06.06.2013)
Published in Molecular cell (06.06.2013)
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Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats
Harriman, Geraldine, Greenwood, Jeremy, Bhat, Sathesh, Huang, Xinyi, Wang, Ruiying, Paul, Debamita, Tong, Liang, Saha, Asish K., Westlin, William F., Kapeller, Rosana, Harwood, H. James
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2016)
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AMPK and SIRT1: a long-standing partnership?
Ruderman, Neil B, Xu, X Julia, Nelson, Lauren, Cacicedo, José M, Saha, Asish K, Lan, Fan, Ido, Yasuo
Published in American journal of physiology: endocrinology and metabolism (01.04.2010)
Published in American journal of physiology: endocrinology and metabolism (01.04.2010)
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Journal Article
Estradiol Regulates Brown Adipose Tissue Thermogenesis via Hypothalamic AMPK
Martínez de Morentin, Pablo B., González-García, Ismael, Martins, Luís, Lage, Ricardo, Fernández-Mallo, Diana, Martínez-Sánchez, Noelia, Ruíz-Pino, Francisco, Liu, Ji, Morgan, Donald A., Pinilla, Leonor, Gallego, Rosalía, Saha, Asish K., Kalsbeek, Andries, Fliers, Eric, Bisschop, Peter H., Diéguez, Carlos, Nogueiras, Rubén, Rahmouni, Kamal, Tena-Sempere, Manuel, López, Miguel
Published in Cell metabolism (01.07.2014)
Published in Cell metabolism (01.07.2014)
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Journal Article
Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
Schoenmakers, Erik, González, Carmen R, Velagapudi, Vidya R, López, Miguel, de Morentin, Pablo Blanco Martínez, Vidal-Puig, Antonio, Chatterjee, Krishna, Rahmouni, Kamal, Vázquez, María J, Oreši, Matej, Morgan, Donald A, Diéguez, Carlos, Agassandian, Khristofor, Varela, Luis, Carling, David, Tovar, Sulay, Rodríguez-Cuenca, Sergio, Lage, Ricardo, Gallego, Rosalía, Nogueiras, Rubén, Lelliott, Christopher, Saha, Asish K
Published in Nature medicine (01.09.2010)
Published in Nature medicine (01.09.2010)
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Journal Article
Downregulation of AMPK Accompanies Leucine- and Glucose-Induced Increases in Protein Synthesis and Insulin Resistance in Rat Skeletal Muscle
SAHA, Asish K, JULIA XU, X, LAWSON, Ebony, DEOLIVEIRA, Rosangela, BRANDON, Amanda E, KRAEGEN, Edward W, RUDERMAN, Neil B
Published in Diabetes (New York, N.Y.) (01.10.2010)
Published in Diabetes (New York, N.Y.) (01.10.2010)
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Journal Article
PKD1 Inhibits AMPKα2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells
Coughlan, Kimberly A., Valentine, Rudy J., Sudit, Bella S., Allen, Katherine, Dagon, Yossi, Kahn, Barbara B., Ruderman, Neil B., Saha, Asish K.
Published in The Journal of biological chemistry (11.03.2016)
Published in The Journal of biological chemistry (11.03.2016)
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Journal Article
Hypothalamic Fatty Acid Metabolism Mediates the Orexigenic Action of Ghrelin
López, Miguel, Lage, Ricardo, Saha, Asish K., Pérez-Tilve, Diego, Vázquez, María J., Varela, Luis, Sangiao-Alvarellos, Susana, Tovar, Sulay, Raghay, Kawtar, Rodríguez-Cuenca, Sergio, Deoliveira, Rosangela M., Castañeda, Tamara, Datta, Rakesh, Dong, Jesse Z., Culler, Michael, Sleeman, Mark W., Álvarez, Clara V., Gallego, Rosalía, Lelliott, Christopher J., Carling, David, Tschöp, Matthias H., Diéguez, Carlos, Vidal-Puig, Antonio
Published in Cell metabolism (01.05.2008)
Published in Cell metabolism (01.05.2008)
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Journal Article
Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells
Suchankova, Gabriela, Nelson, Lauren E., Gerhart-Hines, Zachary, Kelly, Meghan, Gauthier, Marie-Soleil, Saha, Asish K., Ido, Yasuo, Puigserver, Pere, Ruderman, Neil B.
Published in Biochemical and biophysical research communications (23.01.2009)
Published in Biochemical and biophysical research communications (23.01.2009)
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Journal Article
Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues
LeBrasseur, Nathan K, Kelly, Meghan, Tsao, Tsu-Shuen, Farmer, Stephen R, Saha, Asish K, Ruderman, Neil B, Tomas, Eva
Published in American journal of physiology: endocrinology and metabolism (01.07.2006)
Published in American journal of physiology: endocrinology and metabolism (01.07.2006)
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Journal Article
Pregnancy Induces Resistance to the Anorectic Effect of Hypothalamic Malonyl-CoA and the Thermogenic Effect of Hypothalamic AMPK Inhibition in Female Rats
Martínez de Morentin, Pablo B, Lage, Ricardo, González-García, Ismael, Ruíz-Pino, Francisco, Martins, Luís, Fernández-Mallo, Diana, Gallego, Rosalía, Fernø, Johan, Señarís, Rosa, Saha, Asish K, Tovar, Sulay, Diéguez, Carlos, Nogueiras, Rubén, Tena-Sempere, Manuel, López, Miguel
Published in Endocrinology (Philadelphia) (01.03.2015)
Published in Endocrinology (Philadelphia) (01.03.2015)
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Journal Article
Enhanced Muscle Fat Oxidation and Glucose Transport by ACRP30 Globular Domain: Acetyl-CoA Carboxylase Inhibition and AMP-Activated Protein Kinase Activation
Tomas, Eva, Tsao, Tsu-Shuen, Saha, Asish K., Murrey, Heather E., Zhang, Cheng cheng, Itani, Samar I., Lodish, Harvey F., Ruderman, Neil B.
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2002)
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Journal Article
Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats
Coughlan, Kimberly A, Balon, Thomas W, Valentine, Rudy J, Petrocelli, Robert, Schultz, Vera, Brandon, Amanda, Cooney, Gregory J, Kraegen, Edward W, Ruderman, Neil B, Saha, Asish K
Published in PloS one (21.05.2015)
Published in PloS one (21.05.2015)
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Journal Article
Minireview: Malonyl CoA, AMP-Activated Protein Kinase, and Adiposity
Ruderman, Neil B, Saha, Asish K, Kraegen, Edward W
Published in Endocrinology (Philadelphia) (01.12.2003)
Published in Endocrinology (Philadelphia) (01.12.2003)
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Journal Article
Lipopolysaccharide (LPS)-induced septic shock causes profound changes in myocardial energy metabolites in pigs
Lado-Abeal, Joaquin, Martinez-Sánchez, Noelia, Cocho, Jose Angel, Martín-Pastor, Manuel, Castro-Piedras, Isabel, Couce-Pico, M. Luz, Saha, Asish K., López, Miguel
Published in Metabolomics (01.10.2018)
Published in Metabolomics (01.10.2018)
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