Subasumstat, a first-in-class inhibitor of SUMO-activating enzyme, demonstrates dose-dependent target engagement and SUMOylation inhibition, leading to rapid activation of innate and adaptive immune responses in the dose escalation portion of a phase 1/2 clinical study
Saggu, G., Stroopinsky, D., Dudek, A.Z., Olszanski, A.J., Juric, D., Dowlati, A., Vaishampayan, U., Assad, H., Rodón, J., Gibbs, J., Green, J., Du, Z., Rudicell, R., Kannan, K., Gharavi, R., Gomez-Pinillos, A., Fram, R.J., Berger, A., Sachsenmeier, K., Kasar, S.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Synovial accumulation of technetium labelled liposomes in rheumatoid arthritis
Williams, B D, O'Sullivan, M M, Saggu, G S, Williams, K E, Williams, L A, Morgan, J R
Published in Annals of the rheumatic diseases (01.04.1987)
Published in Annals of the rheumatic diseases (01.04.1987)
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Gastric emptying and small bowel transit times in volunteers after intravenous morphine and nalbuphine
Yukioka, H, Rosen, M, Evans, K T, Leach, K G, Hayward, M W, Saggu, G S
Published in Anaesthesia (01.07.1987)
Published in Anaesthesia (01.07.1987)
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Imaging in rheumatoid arthritis using liposomes labelled with technetium
Williams, B D, O'Sullivan, M M, Saggu, G S, Williams, K E, Williams, L A, Morgan, J R
Published in British Medical Journal (Clinical research ed.) (01.11.1986)
Published in British Medical Journal (Clinical research ed.) (01.11.1986)
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Type II endoleaks: challenges and solutions
Brown, Andrew, Saggu, Greta K, Bown, Matthew J, Sayers, Robert D, Sidloff, David A
Published in Vascular health and risk management (01.01.2016)
Published in Vascular health and risk management (01.01.2016)
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