Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial
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Published in The Lancet (British edition) (04.01.2014)
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Trastuzumab with trimodality treatment for oesophageal adenocarcinoma with HER2 overexpression (NRG Oncology/RTOG 1010): a multicentre, randomised, phase 3 trial
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RTOG 0529: A Phase 2 Evaluation of Dose-Painted Intensity Modulated Radiation Therapy in Combination With 5-Fluorouracil and Mitomycin-C for the Reduction of Acute Morbidity in Carcinoma of the Anal Canal
Kachnic, Lisa A., MD, Winter, Kathryn, MS, Myerson, Robert J., MD, Goodyear, Michael D., MD, Willins, John, PhD, Esthappan, Jacqueline, PhD, Haddock, Michael G., MD, Rotman, Marvin, MD, Parikh, Parag J., MD, Safran, Howard, MD, Willett, Christopher G., MD
Published in International journal of radiation oncology, biology, physics (01.05.2013)
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ONC201 and imipridones: Anti-cancer compounds with clinical efficacy
Prabhu, Varun Vijay, Morrow, Sara, Rahman Kawakibi, Abed, Zhou, Lanlan, Ralff, Marie, Ray, Jocelyn, Jhaveri, Aakash, Ferrarini, Isacco, Lee, Young, Parker, Cassandra, Zhang, Yiqun, Borsuk, Robyn, Chang, Wen-I, Honeyman, Joshua N., Tavora, Fabio, Carneiro, Benedito, Raufi, Alexander, Huntington, Kelsey, Carlsen, Lindsey, Louie, Anna, Safran, Howard, Seyhan, Attila A., Tarapore, Rohinton S., Schalop, Lee, Stogniew, Martin, Allen, Joshua E., Oster, Wolfgang, El-Deiry, Wafik S.
Published in Neoplasia (New York, N.Y.) (01.12.2020)
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Oncogenic ALK Fusion in Rare and Aggressive Subtype of Colorectal Adenocarcinoma as a Potential Therapeutic Target
Yakirevich, Evgeny, Resnick, Murray B, Mangray, Shamlal, Wheeler, Michael, Jackson, Cynthia L, Lombardo, Kara A, Lee, Jeeyun, Kim, Kyoung-Mee, Gill, Anthony J, Wang, Kai, Gowen, Kyle, Sun, James, Miller, Vincent A, Stephens, Philip J, Ali, Siraj M, Ross, Jeffrey S, Safran, Howard
Published in Clinical cancer research (01.08.2016)
Published in Clinical cancer research (01.08.2016)
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EZH2i EPZ-6438 and HDACi vorinostat synergize with ONC201/TIC10 to activate integrated stress response, DR5, reduce H3K27 methylation, ClpX and promote apoptosis of multiple tumor types including DIPG
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Published in Neoplasia (New York, N.Y.) (01.08.2021)
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Addition of Algenpantucel-L Immunotherapy to Standard Adjuvant Therapy for Pancreatic Cancer: a Phase 2 Study
Hardacre, Jeffrey M., Mulcahy, Mary, Small, William, Talamonti, Mark, Obel, Jennifer, Krishnamurthi, Smitha, Rocha-Lima, Caio S., Safran, Howard, Lenz, Heinz-Joseph, Chiorean, E. Gabriela
Published in Journal of gastrointestinal surgery (2013)
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Phase II Trial of Cetuximab, Gemcitabine, and Oxaliplatin Followed by Chemoradiation With Cetuximab for Locally Advanced (T4) Pancreatic Adenocarcinoma: Correlation of Smad4(Dpc4) Immunostaining With Pattern of Disease Progression
CRANE, Christopher H, VARADHACHARY, Gauri R, DAS, Prajnan, LEE, Jeffrey E, ABBRUZZESE, James L, WOLFF, Robert A, YORDY, John S, STAERKEL, Gregg A, JAVLE, Milind M, SAFRAN, Howard, HAQUE, Waqar, HOBBS, Bridgett D, KRISHNAN, Sunil, FLEMING, Jason B
Published in Journal of clinical oncology (01.08.2011)
Published in Journal of clinical oncology (01.08.2011)
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Failure to Adhere to Protocol Specified Radiation Therapy Guidelines Was Associated With Decreased Survival in RTOG 9704—A Phase III Trial of Adjuvant Chemotherapy and Chemoradiotherapy for Patients With Resected Adenocarcinoma of the Pancreas
Abrams, Ross A., M.D, Winter, Kathryn A., M.S, Regine, William F., M.D, Safran, Howard, M.D, Hoffman, John P., M.D, Lustig, Robert, M.D, Konski, Andre A., M.D, Benson, Al B., M.D, Macdonald, John S., M.D, Rich, Tyvin A., M.D, Willett, Christopher G., M.D
Published in International journal of radiation oncology, biology, physics (01.02.2012)
Published in International journal of radiation oncology, biology, physics (01.02.2012)
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Postresection CA 19-9 Predicts Overall Survival in Patients With Pancreatic Cancer Treated With Adjuvant Chemoradiation: A Prospective Validation by RTOG 9704
BERGER, Adam C, GARCIA, Miguel, HOFFMAN, John P, REGINE, William F, ABRAMS, Ross A, SAFRAN, Howard, KONSKI, Andre, BENSON, Alan B, MACDONALD, John, WILLETT, Christopher G
Published in Journal of clinical oncology (20.12.2008)
Published in Journal of clinical oncology (20.12.2008)
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Prometastatic secretome trafficking via exosomes initiates pancreatic cancer pulmonary metastasis
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Published in Cancer letters (01.07.2020)
Published in Cancer letters (01.07.2020)
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Analysis of Radiation Therapy Quality Assurance in NRG Oncology RTOG 0848
Tchelebi, Leila T, Winter, Kathryn A, Abrams, Ross A, Safran, Howard P, Regine, William F, McNulty, Susan, Wu, Abraham, Du, Kevin L, Seaward, Samantha A, Bian, Shelly X, Aljumaily, Raid, Shivnani, Anand, Knoble, Jeanna L, Crocenzi, Todd S, DiPetrillo, Thomas A, Roof, Kevin S, Crane, Christopher H, Goodman, Karyn A
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Published in International journal of radiation oncology, biology, physics (01.01.2024)
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Phase I study to assess the effect of adavosertib (AZD1775) on the pharmacokinetics of substrates of CYP1A2, CYP2C19, and CYP3A in patients with advanced solid tumors
Någård, Mats, Ah-See, Mei-Lin, Strauss, James, Wise-Draper, Trisha, Safran, Howard P., Nadeau, Laura, Edenfield, William J., Lewis, Lionel D., Ottesen, Lone H., Li, Yan, Mugundu, Ganesh M.
Published in Cancer chemotherapy and pharmacology (01.09.2023)
Published in Cancer chemotherapy and pharmacology (01.09.2023)
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Adavosertib (AZD1775) does not prolong the QTc interval in patients with advanced solid tumors: a phase I open-label study
Någård, Mats, Ah-See, Mei-Lin, Strauss, James, Wise-Draper, Trisha, Safran, Howard P., Nadeau, Laura, Edenfield, William J., Lewis, Lionel D., Rekić, Dinko, Dota, Corina, Ottesen, Lone H., Li, Yan, Mugundu, Ganesh M.
Published in Cancer chemotherapy and pharmacology (01.08.2023)
Published in Cancer chemotherapy and pharmacology (01.08.2023)
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Clinical activity of 9-ING-41, a small molecule selective glycogen synthase kinase-3 beta (GSK-3β) inhibitor, in refractory adult T-Cell leukemia/lymphoma
Hsu, Andrew, Huntington, Kelsey E., De Souza, Andre, Zhou, Lanlan, Olszewski, Adam J., Makwana, Nirav P., Treaba, Diana O., Cavalcante, Ludimila, Giles, Francis J., Safran, Howard, El-Deiry, Wafik S., Carneiro, Benedito A.
Published in Cancer biology & therapy (31.12.2022)
Published in Cancer biology & therapy (31.12.2022)
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Strategies to sensitize cancer cells to immunotherapy
George, Andrew, Sahin, Ilyas, Carneiro, Benedito A., Dizon, Don S., Safran, Howard P., El-Deiry, Wafik S.
Published in Human vaccines & immunotherapeutics (03.08.2021)
Published in Human vaccines & immunotherapeutics (03.08.2021)
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The Influence of Total Nodes Examined, Number of Positive Nodes, and Lymph Node Ratio on Survival After Surgical Resection and Adjuvant Chemoradiation for Pancreatic Cancer: A Secondary Analysis of RTOG 9704
Showalter, Timothy N., M.D, Winter, Kathryn A., M.S, Berger, Adam C., M.D, Regine, William F., M.D, Abrams, Ross A., M.D, Safran, Howard, M.D, Hoffman, John P., M.D, Benson, Al B., M.D, MacDonald, John S., M.D, Willett, Christopher G., M.D
Published in International journal of radiation oncology, biology, physics (01.12.2011)
Published in International journal of radiation oncology, biology, physics (01.12.2011)
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Eltrombopag for thrombocytopenia in patients with advanced solid tumors receiving gemcitabine-based chemotherapy: a randomized, placebo-controlled phase 2 study
Winer, Eric S., Safran, Howard, Karaszewska, Boguslawa, Bauer, Sebastian, Khan, Dilawar, Doerfel, Steffen, Burgess, Paul, Kalambakas, Stacey, Mostafa Kamel, Yasser, Forget, Frederic
Published in International journal of hematology (01.12.2017)
Published in International journal of hematology (01.12.2017)
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Informed consent in oncology clinical trials: A Brown University Oncology Research Group prospective cross-sectional pilot study
Schumacher, Andrew, Sikov, William M, Quesenberry, Matthew I, Safran, Howard, Khurshid, Humera, Mitchell, Kristen M, Olszewski, Adam J
Published in PloS one (24.02.2017)
Published in PloS one (24.02.2017)
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