Total Syntheses of (+)-Zampanolide and (+)-Dactylolide Exploiting a Unified Strategy
Smith, Amos B, Safonov, Igor G, Corbett, R. Michael
Published in Journal of the American Chemical Society (18.09.2002)
Published in Journal of the American Chemical Society (18.09.2002)
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Identification of 4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a Novel Inhibitor of AKT Kinase
Heerding, Dirk A, Rhodes, Nelson, Leber, Jack D, Clark, Tammy J, Keenan, Richard M, Lafrance, Louis V, Li, Mei, Safonov, Igor G, Takata, Dennis T, Venslavsky, Joseph W, Yamashita, Dennis S, Choudhry, Anthony E, Copeland, Robert A, Lai, Zhihong, Schaber, Michael D, Tummino, Peter J, Strum, Susan L, Wood, Edgar R, Duckett, Derek R, Eberwein, Derek, Knick, Victoria B, Lansing, Timothy J, McConnell, Randy T, Zhang, ShuYun, Minthorn, Elisabeth A, Concha, Nestor O, Warren, Gregory L, Kumar, Rakesh
Published in Journal of medicinal chemistry (25.09.2008)
Published in Journal of medicinal chemistry (25.09.2008)
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Total Synthesis of (+)-Zampanolide
Smith, Amos B, Safonov, Igor G, Corbett, R. Michael
Published in Journal of the American Chemical Society (12.12.2001)
Published in Journal of the American Chemical Society (12.12.2001)
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Tetrasubstituted pyridines as potent and selective AKT inhibitors: Reduced CYP450 and hERG inhibition of aminopyridines
Lin, Hong, Yamashita, Dennis S., Xie, Ren, Zeng, Jin, Wang, Wenyong, Leber, Jack, Safonov, Igor G., Verma, Sharad, Li, Mei, LaFrance, Louis, Venslavsky, Joseph, Takata, Dennis, Luengo, Juan I., Kahana, Jason A., Zhang, Shuyun, Robell, Kimberly A., Levy, Dana, Kumar, Rakesh, Choudhry, Anthony E., Schaber, Michael, Lai, Zhihong, Brown, Barry S., Donovan, Brian T., Minthorn, Elisabeth A., Brown, Kristin K., Heerding, Dirk A.
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
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New benzimidazoles as thrombopoietin receptor agonists
Safonov, Igor G., Heerding, Dirk A., Keenan, Richard M., Price, Alan T., Erickson-Miller, Connie L., Hopson, Christopher B., Levin, Jenna L., Lord, Kenneth A., Tapley, Peter M.
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Identification of 4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3 S )-3-piperidinylmethyl]oxy}-1 H -imidazo[4,5- c ]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a Novel Inhibitor of AKT Kinase
Heerding, Dirk A., Rhodes, Nelson, Leber, Jack D., Clark, Tammy J., Keenan, Richard M., Lafrance, Louis V., Li, Mei, Safonov, Igor G., Takata, Dennis T., Venslavsky, Joseph W., Yamashita, Dennis S., Choudhry, Anthony E., Copeland, Robert A., Lai, Zhihong, Schaber, Michael D., Tummino, Peter J., Strum, Susan L., Wood, Edgar R., Duckett, Derek R., Eberwein, Derek, Knick, Victoria B., Lansing, Timothy J., McConnell, Randy T., Zhang, ShuYun, Minthorn, Elisabeth A., Concha, Nestor O., Warren, Gregory L., Kumar, Rakesh
Published in Journal of medicinal chemistry (25.09.2008)
Published in Journal of medicinal chemistry (25.09.2008)
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Journal Article
Identification of 4-2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-([(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a Novel Inhibitor of AKT Kinase
HEERDING, Dirk A, RHODES, Nelson, YAMASHITA, Dennis S, CHOUDHRY, Anthony E, COPELAND, Robert A, ZHIHONG LAI, SCHABER, Michael D, TUMMINO, Peter J, STRUM, Susan L, WOOD, Edgar R, DUCKETT, Derek R, EBERWEIN, Derek, LEBER, Jack D, KNICK, Victoria B, LANSING, Timothy J, MCCONNELL, Randy T, SHUYUN ZHANG, MINTHORN, Elisabeth A, CONCHA, Nestor O, WARREN, Gregory L, KUMAR, Rakesh, CLARK, Tammy J, KEENAN, Richard M, LAFRANCE, Louis V, MEI LI, SAFONOV, Igor G, TAKATA, Dennis T, VENSLAVSKY, Joseph W
Published in Journal of medicinal chemistry (2008)
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Published in Journal of medicinal chemistry (2008)
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