Therapeutic strategies to alter the oxygen affinity of sickle hemoglobin
Safo, Martin K, Kato, Gregory J
Published in Hematology/oncology clinics of North America (01.04.2014)
Published in Hematology/oncology clinics of North America (01.04.2014)
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Journal Article
The antisickling agent, 5‐hydroxymethyl‐2‐furfural: Other potential pharmacological applications
Pagare, Piyusha P., McGinn, Mina, Ghatge, Mohini S., Shekhar, Vibha, Alhashimi, Rana T., Daniel Pierce, B., Abdulmalik, Osheiza, Zhang, Yan, Safo, Martin K.
Published in Medicinal research reviews (01.11.2024)
Published in Medicinal research reviews (01.11.2024)
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Journal Article
Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia
Sun, Kaiqi, Zhang, Yujin, D’Alessandro, Angelo, Nemkov, Travis, Song, Anren, Wu, Hongyu, Liu, Hong, Adebiyi, Morayo, Huang, Aji, Wen, Yuan E., Bogdanov, Mikhail V., Vila, Alejandro, O’Brien, John, Kellems, Rodney E., Dowhan, William, Subudhi, Andrew W., Jameson-Van Houten, Sonja, Julian, Colleen G., Lovering, Andrew T., Safo, Martin, Hansen, Kirk C., Roach, Robert C., Xia, Yang
Published in Nature communications (15.07.2016)
Published in Nature communications (15.07.2016)
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Journal Article
Crystal structures of influenza A virus matrix protein M1: variations on a theme
Safo, Martin K, Musayev, Faik N, Mosier, Philip D, Zhou, Qibing, Xie, Hang, Desai, Umesh R
Published in PloS one (08.10.2014)
Published in PloS one (08.10.2014)
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Journal Article
Modulating hemoglobin allostery for treatment of sickle cell disease: current progress and intellectual property
Pagare, Piyusha P, Rastegar, Aref, Abdulmalik, Osheiza, Omar, Abdelsattar M, Zhang, Yan, Fleischman, Andrew, Safo, Martin K
Published in Expert opinion on therapeutic patents (01.02.2022)
Published in Expert opinion on therapeutic patents (01.02.2022)
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Journal Article
Functional and structural properties of pyridoxal reductase (PdxI) from Escherichia coli: a pivotal enzyme in the vitamin B6 salvage pathway
Tramonti, Angela, Donkor, Akua K., Parroni, Alessia, Musayev, Faik N., Barile, Anna, Ghatge, Mohini S., Graziani, Claudio, Alkhairi, Mona, AlAwadh, Mohammed, Salvo, Martino Luigi, Safo, Martin K., Contestabile, Roberto
Published in The FEBS journal (01.12.2023)
Published in The FEBS journal (01.12.2023)
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Journal Article
On the catalytic mechanism and stereospecificity of Escherichia coli l‐threonine aldolase
Salvo, Martino L., Remesh, Soumya G., Vivoli, Mirella, Ghatge, Mohini S., Paiardini, Alessandro, D'Aguanno, Simona, Safo, Martin K., Contestabile, Roberto
Published in The FEBS journal (01.01.2014)
Published in The FEBS journal (01.01.2014)
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Journal Article
Exploration of Structure–Activity Relationship of Aromatic Aldehydes Bearing Pyridinylmethoxy-Methyl Esters as Novel Antisickling Agents
Pagare, Piyusha P, Ghatge, Mohini S, Chen, Qiukan, Musayev, Faik N, Venitz, Jurgen, Abdulmalik, Osheiza, Zhang, Yan, Safo, Martin K
Published in Journal of medicinal chemistry (10.12.2020)
Published in Journal of medicinal chemistry (10.12.2020)
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Journal Article
Incorporating valsartan in sesame oil enriched self-nanoemulsifying system-loaded liquisolid tablets to improve its bioavailability
El-Say, Khalid M., Alamri, Sami H., Alsulimani, Helal H., Alharbi, Waleed S., Omar, Abdelsattar M., Safo, Martin K., Ahmed, Tarek A.
Published in International journal of pharmaceutics (25.05.2023)
Published in International journal of pharmaceutics (25.05.2023)
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Journal Article
Quantitative assessment of the in-vitro binding kinetics of antisickling aromatic aldehydes with hemoglobin A: A universal HPLC-UV/Vis method to quantitate Schiff-base adduct formation
Xu, Xiaomeng, Ghatge, Mohini S., Huang, Boshi, Alghamdi, Ahmed, Wang, Huiqun, Pierce, B. Daniel, Abdulmalik, Osheiza, Zhang, Yan, Safo, Martin K., Venitz, Jürgen
Published in Journal of pharmaceutical and biomedical analysis (20.01.2023)
Published in Journal of pharmaceutical and biomedical analysis (20.01.2023)
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Journal Article
Bound water at protein-protein interfaces: partners, roles and hydrophobic bubbles as a conserved motif
Ahmed, Mostafa H, Spyrakis, Francesca, Cozzini, Pietro, Tripathi, Parijat K, Mozzarelli, Andrea, Scarsdale, J Neel, Safo, Martin A, Kellogg, Glen E
Published in PloS one (22.09.2011)
Published in PloS one (22.09.2011)
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3D Interaction Homology: Hydropathic Analyses of the “π–Cation” and “π–π” Interaction Motifs in Phenylalanine, Tyrosine, and Tryptophan Residues
AL Mughram, Mohammed H, Catalano, Claudio, Bowry, John P, Safo, Martin K, Scarsdale, J. Neel, Kellogg, Glen E
Published in Journal of chemical information and modeling (28.06.2021)
Published in Journal of chemical information and modeling (28.06.2021)
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Journal Article
Hemoglobin–ligand binding: Understanding Hb function and allostery on atomic level
Safo, Martin K., Ahmed, Mostafa H., Ghatge, Mohini S., Boyiri, Telih
Published in Biochimica et biophysica acta (01.06.2011)
Published in Biochimica et biophysica acta (01.06.2011)
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