Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents
YOUNG AH KIM, SHARON, Ashoke, CHU, Chung K, RAIS, Reem H, AL SAFARJALANI, Omar N, NAGUIB, Fardos N. M, EL KOUNI, Mahmoud H
Published in Biochemical pharmacology (15.05.2007)
Published in Biochemical pharmacology (15.05.2007)
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Kinetic mechanism of Toxoplasma gondii adenosine kinase and the highly efficient utilization of adenosine
Naguib, Fardos N.M., Rais, Reem H., Al Safarjalani, Omar N., el Kouni, Mahmoud H.
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01.10.2015)
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01.10.2015)
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Metabolism and Selective Toxicity of 6-Nitrobenzylthioinosine in Toxoplasma gondii
EL KOUNI, M. H, GUARCELLO, V, AL SAFARJALANI, O. N, NAGUIB, F. N. M
Published in Antimicrobial Agents and Chemotherapy (01.10.1999)
Published in Antimicrobial Agents and Chemotherapy (01.10.1999)
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Synthesis, biological evaluation and molecular modeling studies of N-benzyladenosine analogues as potential anti-toxoplasma agents
Kim, Young Ah, Sharon, Ashoke, Chu, Chung K, Rais, Reem H, Safarjalani, Omar N Al, Naguib, Fardos N M, el Kouni, Mahmoud H
Published in Biochemical pharmacology (15.05.2007)
Published in Biochemical pharmacology (15.05.2007)
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Structure–activity relationships of carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase
Kim, Young Ah, Rawal, Ravindra K., Yoo, Jakyung, Sharon, Ashoke, Jha, Ashok K., Chu, Chung K., Rais, Reem H., Al Safarjalani, Omar N., Naguib, Fardos N.M., el Kouni, Mahmoud H.
Published in Bioorganic & medicinal chemistry (15.05.2010)
Published in Bioorganic & medicinal chemistry (15.05.2010)
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7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: Activities and selective toxicities
Al Safarjalani, Omar N., Rais, Reem H., Ah Kim, Young, Chu, Chung K., Naguib, Fardos N.M., el Kouni, Mahmoud H.
Published in Biochemical pharmacology (15.10.2008)
Published in Biochemical pharmacology (15.10.2008)
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Journal Article
Structure−Activity Relationships of 7-Deaza-6-benzylthioinosine Analogues as Ligands of Toxoplasma gondii Adenosine Kinase
Kim, Young Ah, Sharon, Ashoke, Chu, Chung K, Rais, Reem H, Al Safarjalani, Omar N, Naguib, Fardos N. M, el Kouni, Mahmoud H
Published in Journal of medicinal chemistry (10.07.2008)
Published in Journal of medicinal chemistry (10.07.2008)
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Journal Article
Carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase: Biological activities and selective toxicities
Al Safarjalani, Omar N., Rais, Reem H., Kim, Young Ah, Chu, Chung K., Naguib, Fardos N.M., el Kouni, Mahmoud H.
Published in Biochemical pharmacology (01.10.2010)
Published in Biochemical pharmacology (01.10.2010)
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5-(Phenylthio)acyclouridine: a powerful enhancer of oral uridine bioavailability : Relevance to chemotherapy with 5-fluorouracil and other uridine rescue regimens
AL SAFARJALANI, Omar N, ZHOU, Xiao-Jian, RAIS, Reem H, JUNXING SHI, SCHINAZI, Raymond F, NAGUIB, Fardos N. M, EL KOUNI, Mahmoud H
Published in Cancer chemotherapy and pharmacology (01.06.2005)
Published in Cancer chemotherapy and pharmacology (01.06.2005)
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Journal Article
6-Benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: Activities and selective toxicities
Rais, Reem H., Al Safarjalani, Omar N., Yadav, Vikas, Guarcello, Vincenzo, Kirk, Marion, Chu, Chung K., Naguib, Fardos N.M., el Kouni, Mahmoud H.
Published in Biochemical pharmacology (15.05.2005)
Published in Biochemical pharmacology (15.05.2005)
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Journal Article
Synthesis, Biological Activity and Molecular Modeling of 6-Benzylthioinosine Analogues as Subversive Substrates of Toxoplasma g ondii Adenosine Kinase
Yadav, Vikas, Chu, Chung K, Rais, Reem H, Al Safarjalani, Omar N, Guarcello, Vincenzo, Naguib, Fardos N. M
Published in Journal of medicinal chemistry (08.04.2004)
Published in Journal of medicinal chemistry (08.04.2004)
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Journal Article
Modulation of 5-fluorouracil host-toxicity and chemotherapeutic efficacy against human colon tumors by 5-(Phenylthio)acyclouridine, a uridine phosphorylase inhibitor
AL SAFARJALANI, Omar N, RAIS, Reem, JUNXING SHI, SCHINAZI, Raymond F, NAGUIB, Fardos N. M, EL KOUNI, Mahmoud H
Published in Cancer chemotherapy and pharmacology (01.11.2006)
Published in Cancer chemotherapy and pharmacology (01.11.2006)
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Modulation of 5-fluorouracil host toxicity by 5-(benzyloxybenzyl)barbituric acid acyclonucleoside, a uridine phosphorylase inhibitor, and 2′,3′,5′-tri- O-acetyluridine, a prodrug of uridine
Ashour, Osama M, Naguib, Fardos N.M, Panzica, Raymond P, Al Safarjalani, Omar N, el Kouni, Mahmoud H
Published in Biochemical pharmacology (01.08.2000)
Published in Biochemical pharmacology (01.08.2000)
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Journal Article
Synthesis, Biological Activity and Molecular Modeling of 6-Benzylthioinosine Analogues as Subversive Substrates of Toxoplasma gondii Adenosine Kinase
YADAV, Vikas, CHU, Chung K., RAIS, Reem H., AL SAFARJALANI, Omar N., GUARCELLO, Vincenzo, NAGUIB, Fardos N. M.
Published in Journal of medicinal chemistry (08.04.2004)
Published in Journal of medicinal chemistry (08.04.2004)
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Journal Article
Enhancement of the bioavailability of oral uridine by coadministration of 5-(phenylthio)acyclouridine, a uridine phosphorylase inhibitor: implications for uridine rescue regimens in chemotherapy
AL SAFARJALANI, Omar N, ZHOU, Xiao-Jian, NAGUIB, Fardos N. M, JUNXING SHI, SCHINAZI, Raymond F, EL KOUNI, Mahmound H
Published in Cancer chemotherapy and pharmacology (01.11.2001)
Published in Cancer chemotherapy and pharmacology (01.11.2001)
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Journal Article
Synthesis, biological evaluation and molecular modeling studies of N 6-benzyladenosine analogues as potential anti-toxoplasma agents
Kim, Young Ah, Sharon, Ashoke, Chu, Chung K., Rais, Reem H., Al Safarjalani, Omar N., Naguib, Fardos N.M., el Kouni, Mahmoud H.
Published in Biochemical pharmacology (15.05.2007)
Published in Biochemical pharmacology (15.05.2007)
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Journal Article
Uridine phosphorylase inhibitors: Chemical modification of benzyloxybenzyl-barbituric acid and its effects on UrdPase inhibition
Guerin, David J., Mazeas, Daniel, Musale, Manoj S., Naguib, Fardos N.M., Al Safarjalani, Omar N., el Kouni, Mahmoud H., Panzica, Raymond P.
Published in Bioorganic & medicinal chemistry letters (07.06.1999)
Published in Bioorganic & medicinal chemistry letters (07.06.1999)
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