The ability of molecular docking to unravel the controversy and challenges related to P-glycoprotein—a well-known, yet poorly understood drug transporter
Zeino, Maen, Saeed, Mohamed E. M., Kadioglu, Onat, Efferth, Thomas
Published in Investigational new drugs (01.08.2014)
Published in Investigational new drugs (01.08.2014)
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Journal Article
Chemopreventive Property of Sencha Tea Extracts towards Sensitive and Multidrug-Resistant Leukemia and Multiple Myeloma Cells
Lu, Xiaohua, Saeed, Mohamed E M, Hegazy, Mohamed-Elamir F, Kampf, Christopher J, Efferth, Thomas
Published in Biomolecules (Basel, Switzerland) (04.07.2020)
Published in Biomolecules (Basel, Switzerland) (04.07.2020)
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Journal Article
Targeting epidermal growth factor receptors and downstream signaling pathways in cancer by phytochemicals
Kadioglu, Onat, Cao, Jingming, Saeed, Mohamed E. M., Greten, Henry Johannes, Efferth, Thomas
Published in Targeted Oncology (01.09.2015)
Published in Targeted Oncology (01.09.2015)
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Journal Article
Book Review
Identification of novel drug resistance mechanisms by genomic and transcriptomic profiling of glioblastoma cells with mutation-activated EGFR
Kadioglu, Onat, Saeed, Mohamed E.M., Mahmoud, Nuha, Azawi, Shaymaa, Mrasek, Kristin, Liehr, Thomas, Efferth, Thomas
Published in Life sciences (1973) (01.11.2021)
Published in Life sciences (1973) (01.11.2021)
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Journal Article
Synthesis of Thymoquinone–Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents
Fröhlich, Tony, Reiter, Christoph, Saeed, Mohamed E. M, Hutterer, Corina, Hahn, Friedrich, Leidenberger, Maria, Friedrich, Oliver, Kappes, Barbara, Marschall, Manfred, Efferth, Thomas, Tsogoeva, Svetlana B
Published in ACS medicinal chemistry letters (14.06.2018)
Published in ACS medicinal chemistry letters (14.06.2018)
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Journal Article
Anti-inflammatory and tight junction protective activity of the herbal preparation STW 5-II on mouse intestinal organoids
Elbadawi, Mohamed, Ammar, Ramy M., Aziz-Kalbhenn, Heba, Rabini, Sabine, Klauck, Sabine M., Dawood, Mona, Saeed, Mohamed E M, Kampf, Christopher J., Efferth, Thomas
Published in Phytomedicine (Stuttgart) (15.07.2021)
Published in Phytomedicine (Stuttgart) (15.07.2021)
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Journal Article
In Silico and In Vitro Screening of 50 Curcumin Compounds as EGFR and NF-κB Inhibitors
Saeed, Mohamed E M, Yücer, Rümeysa, Dawood, Mona, Hegazy, Mohamed-Elamir F, Drif, Assia, Ooko, Edna, Kadioglu, Onat, Seo, Ean-Jeong, Kamounah, Fadhil S, Titinchi, Salam J, Bachmeier, Beatrice, Efferth, Thomas
Published in International journal of molecular sciences (02.04.2022)
Published in International journal of molecular sciences (02.04.2022)
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Journal Article
Prevention of carcinogenesis and metastasis by Artemisinin-type drugs
Abba, Mohammed L., Patil, Nitin, Leupold, Jörg Hendrik, Saeed, Mohamed E.M., Efferth, Thomas, Allgayer, Heike
Published in Cancer letters (10.08.2018)
Published in Cancer letters (10.08.2018)
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Journal Article
Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR)
Saeed, Mohamed E M, Mahmoud, Nuha, Sugimoto, Yoshikazu, Efferth, Thomas, Abdel-Aziz, Heba
Published in Frontiers in pharmacology (15.05.2018)
Published in Frontiers in pharmacology (15.05.2018)
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Journal Article
Molecular Determinants of Sensitivity or Resistance of Cancer Cells Toward Sanguinarine
Saeed, Mohamed E M, Mahmoud, Nuha, Sugimoto, Yoshikazu, Efferth, Thomas, Abdel-Aziz, Heba
Published in Frontiers in pharmacology (26.02.2018)
Published in Frontiers in pharmacology (26.02.2018)
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Journal Article
Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma
Saeed, Mohamed E. M., Kadioglu, Onat, Greten, Henry Johannes, Yildirim, Adem, Mayr, Katharina, Wenz, Frederik, Giordano, Frank A., Efferth, Thomas
Published in Investigational new drugs (01.06.2021)
Published in Investigational new drugs (01.06.2021)
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Journal Article
Repurposing of the ALK Inhibitor Crizotinib for Acute Leukemia and Multiple Myeloma Cells
Boulos, Joelle C., Saeed, Mohamed E. M., Chatterjee, Manik, Bülbül, Yagmur, Crudo, Francesco, Marko, Doris, Munder, Markus, Klauck, Sabine M., Efferth, Thomas
Published in Pharmaceuticals (Basel, Switzerland) (05.11.2021)
Published in Pharmaceuticals (Basel, Switzerland) (05.11.2021)
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Journal Article
Identification of metastasis-related genes by genomic and transcriptomic studies in murine melanoma
Kadioglu, Onat, Saeed, Mohamed E.M., Mahmoud, Nuha, Hussein Azawi, Shaymaa S., Rincic, Martina, Liehr, Thomas, Efferth, Thomas
Published in Life sciences (1973) (15.02.2021)
Published in Life sciences (1973) (15.02.2021)
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Journal Article
Modulation of P-glycoprotein activity by novel synthetic curcumin derivatives in sensitive and multidrug-resistant T-cell acute lymphoblastic leukemia cell lines
Ooko, Edna, Alsalim, Tahseen, Saeed, Bahjat, Saeed, Mohamed E.M., Kadioglu, Onat, Abbo, Hanna S., Titinchi, Salam J.J., Efferth, Thomas
Published in Toxicology and applied pharmacology (15.08.2016)
Published in Toxicology and applied pharmacology (15.08.2016)
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Journal Article
Disruption of Lipid Raft Microdomains, Regulation of CD38, TP53, and MYC Signaling, and Induction of Apoptosis by Lomitapide in Multiple Myeloma Cells
SAEED, MOHAMED E. M., BOULOS, JOELLE C., MÜCKLICH, SABRINA B., LEICH, ELLEN, CHATTERJEE, MANIK, KLAUCK, SABINE M., EFFERTH, THOMAS
Published in Cancer genomics & proteomics (01.09.2022)
Published in Cancer genomics & proteomics (01.09.2022)
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Journal Article