Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
Fraietta, Joseph A, Lacey, Simon F, Orlando, Elena J, Pruteanu-Malinici, Iulian, Gohil, Mercy, Lundh, Stefan, Boesteanu, Alina C, Wang, Yan, O'Connor, Roddy S, Hwang, Wei-Ting, Pequignot, Edward, Ambrose, David E, Zhang, Changfeng, Wilcox, Nicholas, Bedoya, Felipe, Dorfmeier, Corin, Chen, Fang, Tian, Lifeng, Parakandi, Harit, Gupta, Minnal, Young, Regina M, Johnson, F Brad, Kulikovskaya, Irina, Liu, Li, Xu, Jun, Kassim, Sadik H, Davis, Megan M, Levine, Bruce L, Frey, Noelle V, Siegel, Donald L, Huang, Alexander C, Wherry, E John, Bitter, Hans, Brogdon, Jennifer L, Porter, David L, June, Carl H, Melenhorst, J Joseph
Published in Nature medicine (01.05.2018)
Published in Nature medicine (01.05.2018)
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Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor
Kochenderfer, James N, Dudley, Mark E, Kassim, Sadik H, Somerville, Robert P T, Carpenter, Robert O, Stetler-Stevenson, Maryalice, Yang, James C, Phan, Giao Q, Hughes, Marybeth S, Sherry, Richard M, Raffeld, Mark, Feldman, Steven, Lu, Lily, Li, Yong F, Ngo, Lien T, Goy, Andre, Feldman, Tatyana, Spaner, David E, Wang, Michael L, Chen, Clara C, Kranick, Sarah M, Nath, Avindra, Nathan, Debbie-Ann N, Morton, Kathleen E, Toomey, Mary Ann, Rosenberg, Steven A
Published in Journal of clinical oncology (20.02.2015)
Published in Journal of clinical oncology (20.02.2015)
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Journal Article
A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-term follow-up and correlates with response
Robbins, Paul F, Kassim, Sadik H, Tran, Thai L N, Crystal, Jessica S, Morgan, Richard A, Feldman, Steven A, Yang, James C, Dudley, Mark E, Wunderlich, John R, Sherry, Richard M, Kammula, Udai S, Hughes, Marybeth S, Restifo, Nicholas P, Raffeld, Mark, Lee, Chyi-Chia R, Li, Yong F, El-Gamil, Mona, Rosenberg, Steven A
Published in Clinical cancer research (01.03.2015)
Published in Clinical cancer research (01.03.2015)
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Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma
Zhang, Ling, Morgan, Richard A, Beane, Joal D, Zheng, Zhili, Dudley, Mark E, Kassim, Sadik H, Nahvi, Azam V, Ngo, Lien T, Sherry, Richard M, Phan, Giao Q, Hughes, Marybeth S, Kammula, Udai S, Feldman, Steven A, Toomey, Mary Ann, Kerkar, Sid P, Restifo, Nicholas P, Yang, James C, Rosenberg, Steven A
Published in Clinical cancer research (15.05.2015)
Published in Clinical cancer research (15.05.2015)
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Journal Article
Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation
Kochenderfer, James N., Dudley, Mark E., Carpenter, Robert O., Kassim, Sadik H., Rose, Jeremy J., Telford, William G., Hakim, Frances T., Halverson, David C., Fowler, Daniel H., Hardy, Nancy M., Mato, Anthony R., Hickstein, Dennis D., Gea-Banacloche, Juan C., Pavletic, Steven Z., Sportes, Claude, Maric, Irina, Feldman, Steven A., Hansen, Brenna G., Wilder, Jennifer S., Blacklock-Schuver, Bazetta, Jena, Bipulendu, Bishop, Michael R., Gress, Ronald E., Rosenberg, Steven A.
Published in Blood (12.12.2013)
Published in Blood (12.12.2013)
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Single-cell multiplexed cytokine profiling of CD19 CAR-T cells reveals a diverse landscape of polyfunctional antigen-specific response
Xue, Qiong, Bettini, Emily, Paczkowski, Patrick, Ng, Colin, Kaiser, Alaina, McConnell, Timothy, Kodrasi, Olja, Quigley, Máire F, Heath, James, Fan, Rong, Mackay, Sean, Dudley, Mark E, Kassim, Sadik H, Zhou, Jing
Published in Journal for immunotherapy of cancer (21.11.2017)
Published in Journal for immunotherapy of cancer (21.11.2017)
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Journal Article
The Bespoke Gene Therapy Consortium: facilitating development of AAV gene therapies for rare diseases
Brooks, P J, Miller, Timothy M, Revah, Frédéric, Suh, Junghae, Garrison, Bradley R, Starke, Lawrence C, MacLachlan, Timothy K, Neilan, Edward G, Raychaudhuri, Gopa, Kassim, Sadik H, Dehdashti, Jean, Rutter, Joni L
Published in Nature reviews. Drug discovery (01.03.2024)
Published in Nature reviews. Drug discovery (01.03.2024)
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Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis
Kassim, Sadik H, Li, Hui, Vandenberghe, Luk H, Hinderer, Christian, Bell, Peter, Marchadier, Dawn, Wilson, Aisha, Cromley, Debra, Redon, Valeska, Yu, Hongwei, Wilson, James M, Rader, Daniel J
Published in PloS one (19.10.2010)
Published in PloS one (19.10.2010)
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Journal Article
Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia
Kassim, Sadik H, Li, Hui, Bell, Peter, Somanathan, Suryanarayan, Lagor, William, Jacobs, Frank, Billheimer, Jeffrey, Wilson, James M, Rader, Daniel J
Published in Human gene therapy (01.01.2013)
Published in Human gene therapy (01.01.2013)
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Journal Article
Author Correction: Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
Fraietta, Joseph A, Lacey, Simon F, Orlando, Elena J, Pruteanu-Malinici, Iulian, Gohil, Mercy, Lundh, Stefan, Boesteanu, Alina C, Wang, Yan, O'Connor, Roddy S, Hwang, Wei-Ting, Pequignot, Edward, Ambrose, David E, Zhang, Changfeng, Wilcox, Nicholas, Bedoya, Felipe, Dorfmeier, Corin, Chen, Fang, Tian, Lifeng, Parakandi, Harit, Gupta, Minnal, Young, Regina M, Johnson, F Brad, Kulikovskaya, Irina, Liu, Li, Xu, Jun, Kassim, Sadik H, Davis, Megan M, Levine, Bruce L, Frey, Noelle V, Siegel, Donald L, Huang, Alexander C, Wherry, E John, Bitter, Hans, Brogdon, Jennifer L, Porter, David L, June, Carl H, Melenhorst, J Joseph
Published in Nature medicine (01.03.2021)
Published in Nature medicine (01.03.2021)
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Journal Article
In Vivo Ablation of CD11c-Positive Dendritic Cells Increases Susceptibility to Herpes Simplex Virus Type 1 Infection and Diminishes NK and T-Cell Responses
Kassim, Sadik H, Rajasagi, Naveen K, Zhao, Xiangyi, Chervenak, Robert, Jennings, Stephen R
Published in Journal of Virology (01.04.2006)
Published in Journal of Virology (01.04.2006)
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Journal Article
Systematic identification of novel SLE related autoantibodies responsible for type I IFN production in human plasmacytoid dendritic cells
Kassim, Sadik H., Jordan, Jarrat, Schreiter, Jessica, Adhikarakunnathu, Sreedevi, Baribaud, Fred, San Mateo, Lani
Published in Cellular immunology (01.07.2013)
Published in Cellular immunology (01.07.2013)
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Journal Article
Dendritic Cells Are Required for Optimal Activation of Natural Killer Functions following Primary Infection with Herpes Simplex Virus Type 1
KASSIM, Sadik H, RAJASAGI, Naveen K, RITZ, Barry W, PRUETT, Stephen B, GARDNER, Elizabeth M, CHERVENAK, Robert, JENNINGS, Stephen R
Published in Journal of Virology (01.04.2009)
Published in Journal of Virology (01.04.2009)
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