Discovery of 3,6-disubstituted pyridazines as a novel class of anticancer agents targeting cyclin-dependent kinase 2: synthesis, biological evaluation and in silico insights
Sabt, Ahmed, Eldehna, Wagdy M., Al-Warhi, Tarfah, Alotaibi, Ohoud J., Elaasser, Mahmoud M., Suliman, Howayda, Abdel-Aziz, Hatem A.
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
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Journal Article
Novel coumarin-6-sulfonamides as apoptotic anti-proliferative agents: synthesis, in vitro biological evaluation, and QSAR studies
Sabt, Ahmed, Abdelhafez, Omaima M., El-Haggar, Radwan S., Madkour, Hassan M. F., Eldehna, Wagdy M., El-Khrisy, Ezz El-Din A. M., Abdel-Rahman, Mohamed A., Rashed, Laila. A.
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2018)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2018)
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Journal Article
Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors
Sabt, Ahmed, Kitsos, Stefanos, Ebaid, Manal S, Furlan, Veronika, Pantiora, Panagiota D, Tsolka, Magdalini, Elkaeed, Eslam B, Hamissa, Mohamed Farouk, Angelis, Nikolaos, Tsitsilonis, Ourania E, Papageorgiou, Anastassios C, Bren, Urban, Labrou, Nikolaos E
Published in PloS one (14.08.2024)
Published in PloS one (14.08.2024)
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Journal Article
Identification of 2-(N-aryl-1,2,3-triazol-4-yl) quinoline derivatives as antitubercular agents endowed with InhA inhibitory activity
Sabt, Ahmed, Abdulla, Maha-Hamadien, Ebaid, Manal S., Pawełczyk, Jakub, Abd El Salam, Hayam A., Son, Ninh The, Ha, Nguyen Xuan, Vaali Mohammed, Mansoor-Ali, Traiki, Thamer, Elsawi, Ahmed E., Dziadek, Bozena, Dziadek, Jaroslaw, Eldehna, Wagdy M.
Published in Frontiers in chemistry (07.08.2024)
Published in Frontiers in chemistry (07.08.2024)
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Journal Article
PDE6D Inhibitors with a New Design Principle Selectively Block K‑Ras Activity
Siddiqui, Farid A, Alam, Catharina, Rosenqvist, Petja, Ora, Mikko, Sabt, Ahmed, Manoharan, Ganesh babu, Bindu, Lakshman, Okutachi, Sunday, Catillon, Marie, Taylor, Troy, Abdelhafez, Omaima M, Lönnberg, Harri, Stephen, Andrew G, Papageorgiou, Anastassios C, Virta, Pasi, Abankwa, Daniel
Published in ACS omega (14.01.2020)
Published in ACS omega (14.01.2020)
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Journal Article
Recent advancements of coumarin-based anticancer agents: An up-to-date review
Al-Warhi, Tarfah, Sabt, Ahmed, Elkaeed, Eslam B., Eldehna, Wagdy M.
Published in Bioorganic chemistry (01.10.2020)
Published in Bioorganic chemistry (01.10.2020)
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Journal Article
New antileishmanial quinoline linked isatin derivatives targeting DHFR-TS and PTR1: Design, synthesis, and molecular modeling studies
Sabt, Ahmed, Eldehna, Wagdy M., Ibrahim, Tamer M., Bekhit, Adnan A., Batran, Rasha Z.
Published in European journal of medicinal chemistry (15.01.2023)
Published in European journal of medicinal chemistry (15.01.2023)
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Journal Article
Design, synthesis and computational studies of new azaheterocyclic coumarin derivatives as anti- Mycobacterium tuberculosis agents targeting enoyl acyl carrier protein reductase (InhA)
Batran, Rasha Z., Sabt, Ahmed, Dziadek, Jarosław, Kassem, Asmaa F.
Published in RSC advances (05.07.2024)
Published in RSC advances (05.07.2024)
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Journal Article
Antibacterial Activity of Quinoline‐Based Derivatives against Methicillin‐Resistant Staphylococcus aureus and Pseudomonas aeruginosa: Design, Synthesis, DFT and Molecular Dynamic Simulations
Sabt, Ahmed, Abdelraof, Mohamed, Hamissa, Mohamed Farouk, Noamaan, Mahmoud A.
Published in Chemistry & biodiversity (01.11.2023)
Published in Chemistry & biodiversity (01.11.2023)
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Journal Article
Investigation of Novel Mucorales Fungal Inhibitors: Synthesis, In‐Silico Study and Anti‐Fungal Potency of Novel Class of Coumarin‐6‐Sulfonamides‐Thiazole and Thiadiazole Hybrids
Sabt, Ahmed, Abdelrahman, Mohamad T., Abdelraof, Mohamed, Rashdan, Huda R. M.
Published in ChemistrySelect (Weinheim) (06.05.2022)
Published in ChemistrySelect (Weinheim) (06.05.2022)
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Journal Article
DFT and molecular simulation validation of the binding activity of PDE[delta] inhibitors for repression of oncogenic k-Ras
Majrashi, Taghreed A, Sabt, Ahmed, Almahli, Hadia, El Hassab, Mahmoud A, Noamaan, Mahmoud A, Elkaeed, Eslam B, Hamissa, Mohamed Farouk, Maslamani, Abdalkareem Nael, Shaldam, Moataz A, Eldehna, Wagdy M
Published in PloS one (08.03.2024)
Published in PloS one (08.03.2024)
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Journal Article
Simultaneous removal of Pb 2+ and direct red 31 dye from contaminated water using N -(2-hydroxyethyl)-2-oxo-2 H -chromene-3-carboxamide loaded chitosan nanoparticles
El-Naggar, Mehrez E., Radwan, Emad K., Rashdan, Huda R. M., El-Wakeel, Shaimaa T., Koryam, Asmaa A., Sabt, Ahmed
Published in RSC advances (22.06.2022)
Published in RSC advances (22.06.2022)
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Journal Article
New pyrazolylindolin-2-one based coumarin derivatives as anti-melanoma agents: design, synthesis, dual BRAF/VEGFR-2 inhibition, and computational studies
Sabt, Ahmed, Khedr, Mohammed A, Eldehna, Wagdy M, Elshamy, Abdelsamed I, Abdelhameed, Mohamed F, Allam, Rasha M, Batran, Rasha Z
Published in RSC advances (16.02.2024)
Published in RSC advances (16.02.2024)
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Journal Article
4-Phenylcoumarin derivatives as new HIV-1 NNRTIs: Design, synthesis, biological activities, and computational studies
Batran, Rasha Z., Sabt, Ahmed, Khedr, Mohammed A., Allayeh, Abdou K., Pannecouque, Christophe, Kassem, Asmaa F.
Published in Bioorganic chemistry (01.12.2023)
Published in Bioorganic chemistry (01.12.2023)
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Journal Article
DFT and molecular simulation validation of the binding activity of PDEδ inhibitors for repression of oncogenic k-Ras
Majrashi, Taghreed A, Sabt, Ahmed, Almahli, Hadia, El Hassab, Mahmoud A, Noamaan, Mahmoud A, Elkaeed, Eslam B, Hamissa, Mohamed Farouk, Maslamani, Abdalkareem Nael, Shaldam, Moataz A, Eldehna, Wagdy M
Published in PloS one (08.03.2024)
Published in PloS one (08.03.2024)
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Journal Article
New pyrazolylindolin-2-one based coumarin derivatives as anti-melanoma agents: design, synthesis, dual BRAF V600E /VEGFR-2 inhibition, and computational studies
Sabt, Ahmed, Khedr, Mohammed A, Eldehna, Wagdy M, Elshamy, Abdelsamed I, Abdelhameed, Mohamed F, Allam, Rasha M, Batran, Rasha Z
Published in RSC advances (14.02.2024)
Published in RSC advances (14.02.2024)
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Journal Article
Modulating leishmanial pteridine metabolism machinery via some new coumarin-1,2,3-triazoles: Design, synthesis and computational studies
Hassan, Nayera W., Sabt, Ahmed, El-Attar, Maryam A.Z., Ora, Mikko, Bekhit, Alaa El-Din A., Amagase, Kikuko, Bekhit, Adnan A., Belal, Ahmed S.F., Elzahhar, Perihan A.
Published in European journal of medicinal chemistry (05.05.2023)
Published in European journal of medicinal chemistry (05.05.2023)
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Journal Article
Discovery of new quinoline derivatives bearing 1-aryl-1,2,3-triazole motif as influenza H1N1 virus neuraminidase inhibitors
Sabt, Ahmed, Khaleel, Eman F., Shaldam, Moataz A., Ebaid, Manal S., Mustafa Badi, Rehab, Allayeh, Abdou K., Eldehna, Wagdy M., Dziadek, Jaroslaw
Published in Bioorganic chemistry (01.10.2024)
Published in Bioorganic chemistry (01.10.2024)
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Journal Article