A spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury in patients with stone disease
Canela, Victor Hugo, Bowen, William S., Ferreira, Ricardo Melo, Syed, Farooq, Lingeman, James E., Sabo, Angela R., Barwinska, Daria, Winfree, Seth, Lake, Blue B., Cheng, Ying-Hua, Gaut, Joseph P., Ferkowicz, Michael, LaFavers, Kaice A., Zhang, Kun, Coe, Fredric L., Worcester, Elaine, Jain, Sanjay, Eadon, Michael T., Williams, James C., El-Achkar, Tarek M.
Published in Nature communications (19.07.2023)
Published in Nature communications (19.07.2023)
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Integration of spatial and single-cell transcriptomics localizes epithelial cell-immune cross-talk in kidney injury
Melo Ferreira, Ricardo, Sabo, Angela R, Winfree, Seth, Collins, Kimberly S, Janosevic, Danielle, Gulbronson, Connor J, Cheng, Ying-Hua, Casbon, Lauren, Barwinska, Daria, Ferkowicz, Michael J, Xuei, Xiaoling, Zhang, Chi, Dunn, Kenneth W, Kelly, Katherine J, Sutton, Timothy A, Hato, Takashi, Dagher, Pierre C, El-Achkar, Tarek M, Eadon, Michael T
Published in JCI insight (22.06.2021)
Published in JCI insight (22.06.2021)
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Label‐free imaging of non‐deparaffinized sections of the human kidney to determine tissue quality and signatures of disease
Sabo, Angela R., Winfree, Seth, Bledsoe, Sharon B., Phillips, Carrie L., Lingeman, James E., Eadon, Michael T., Williams, James C., El‐Achkar, Tarek M.
Published in Physiological reports (01.02.2022)
Published in Physiological reports (01.02.2022)
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The kidney releases a nonpolymerizing form of uromodulin in the urine and circulation that retains the external hydrophobic patch domain
Micanovic, Radmila, LaFavers, Kaice A, Patidar, Kavish R, Ghabril, Marwan S, Doud, Emma H, Mosley, Amber L, Sabo, Angela R, Khan, Shehnaz, El-Achkar, Tarek M
Published in American journal of physiology. Renal physiology (01.04.2022)
Published in American journal of physiology. Renal physiology (01.04.2022)
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Integrated Cytometry With Machine Learning Applied to High-Content Imaging of Human Kidney Tissue for In Situ Cell Classification and Neighborhood Analysis
Winfree, Seth, McNutt, Andrew T., Khochare, Suraj, Borgard, Tyler J., Barwinska, Daria, Sabo, Angela R., Ferkowicz, Michael J., Williams, James C., Lingeman, James E., Gulbronson, Connor J., Kelly, Katherine J., Sutton, Timothy A., Dagher, Pierre C., Eadon, Michael T., Dunn, Kenneth W., El-Achkar, Tarek M.
Published in Laboratory investigation (01.06.2023)
Published in Laboratory investigation (01.06.2023)
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Journal Article
Myeloid Cell Deletion of the Cationic Channel TRPM2, a Target of Uromodulin Inhibition, Is Protective in Murine Sepsis: SA-PO183
LaFavers, Kaice A., Sabo, Angela R., Rhodes, George, El-Achkar, Tarek M.
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Uromodulin Deficiency Shapes AKI Severity by Enhanced Oxidative Injury and Stress Response in Proximal Tubules With Early Activation of the Inflammasome: FR-PO150
LaFavers, Kaice A., Micanovic, Radmila, Sabo, Angela R., Khan, Shehnaz, Winfree, Seth, El-Achkar, Tarek M.
Published in Journal of the American Society of Nephrology (01.11.2022)
Published in Journal of the American Society of Nephrology (01.11.2022)
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Journal Article
CODEX Multiplex Imaging Uncovers Unique Cell Types, States, and Niches in Health and Disease: TH-OR41
Barwinska, Daria, Sabo, Angela R., Winfree, Seth, Gulbronson, Connor J., Eadon, Michael T., Williams, James C., El-Achkar, Tarek M.
Published in Journal of the American Society of Nephrology (01.11.2022)
Published in Journal of the American Society of Nephrology (01.11.2022)
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Journal Article
Integration of CODEX and Brightfield Histology for Cell Type Segmentation and Classification Using Deep Learning: FR-PO029
Lucarelli, Nicholas, Winfree, Seth, Sabo, Angela R., Border, Samuel, Barwinska, Daria, Laszik, Zoltan G., Eadon, Michael T., El-Achkar, Tarek M., Jain, Sanjay, Sarder, Pinaki
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Journal Article
Detection of Myeloid Cell Pleiotropy In Situ and the Unique Niches of Immune Cells in Ischemic Kidney Injury Using CODEX Imaging: FR-PO149
Sabo, Angela R., Maghak, Lauren A., Gulbronson, Connor J., Khan, Shehnaz, Micanovic, Radmila, LaFavers, Kaice A., Barwinska, Daria, Williams, James C., El-Achkar, Tarek M., Winfree, Seth
Published in Journal of the American Society of Nephrology (01.11.2022)
Published in Journal of the American Society of Nephrology (01.11.2022)
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Journal Article
Proximal Tubule Neighborhood in AKI, CKD, and Healthy Control Kidney Tissue Using Spatial Transcriptomics: FR-PO017
Asghari, Mahla, Ferreira, Ricardo Melo, Cheng, Ying-Hua, Gisch, Debora L., Barwinska, Daria, Sabo, Angela R., Kretzler, Matthias, Himmelfarb, Jonathan, Dagher, Pierre C., Winfree, Seth, Jain, Sanjay, El-Achkar, Tarek M., Eadon, Michael T.
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Journal Article
Diverse Immune, Stromal, and Vascular Niches Along the Cortico-Medullary Axis of the Human Kidneys by Integrating 10 Different Modalities Performed on the Same Tissue Block: FR-PO021
Winfree, Seth, Lake, Blue, Ferreira, Ricardo Melo, Fung, Anthony A., Sabo, Angela R., Kaushal, Madhurima, Barwinska, Daria, Zhang, Bo, Gaut, Joseph, Zhang, Kun, Shi, Lingyan, Eadon, Michael T., El-Achkar, Tarek M., Jain, Sanjay
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Journal Article
A Spatial Atlas of the Human Kidneys of Cell Types and Functional Tissue Units Identified in Highly Multiplexed Immunofluorescence Images: FR-OR57
Winfree, Seth, Sabo, Angela R., Barwinska, Daria, Cheng, Ying-Hua, Bowen, William S., Ferkowicz, Michael J., Ferreira, Ricardo Melo, Kaushal, Madhurima, Gaut, Joseph, Eadon, Michael T., El-Achkar, Tarek M., Jain, Sanjay
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Journal Article
Spatial Mapping of Mesangial Cell Proliferative Signatures in the Diabetic Kidney: TH-PO183
ferreira, Ricardo Melo, Asghari, Mahla, Phillips, Carrie L., Parikh, Samir V., Barwinska, Daria, Ferkowicz, Michael J., Sabo, Angela R., Sutton, Timothy A., Cheng, Ying-Hua, Rovin, Brad H., El-Achkar, Tarek M., Dagher, Pierre C., Kelly, Katherine J., Eadon, Michael T.
Published in Journal of the American Society of Nephrology (01.11.2022)
Published in Journal of the American Society of Nephrology (01.11.2022)
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Journal Article
Spatially Localized Mesangial Cell Communication in Diabetic Kidney Disease: FR-OR32
Ferreira, Ricardo Melo, Phillips, Carrie L., Asghari, Mahla, Gisch, Debora L., Barwinska, Daria, Ferkowicz, Michael J., Sabo, Angela R., Lake, Blue, Sutton, Timothy A., Guo, Shunhua, Cheng, Ying-Hua, Alpers, Charles E., Jain, Sanjay, El-Achkar, Tarek M., Dagher, Pierre C., Kelly, Katherine J., Eadon, Michael T.
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Journal Article
Second Harmonic Generation and Fluorescence Imaging Reveal Collagen Fibrils and Cell Nuclei in Mature Randall Plaque: PO0313
Canela, Victor Hugo, Bledsoe, Sharon B., Winfree, Seth, Sabo, Angela R., Worcester, Elaine M., El-Achkar, Tarek M., Williams, James C.
Published in Journal of the American Society of Nephrology (01.10.2020)
Published in Journal of the American Society of Nephrology (01.10.2020)
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Journal Article
Co-Registered Spatial Proteomics and Transcriptomics Identifies Scattered Proximal Tubule Cells: FR-PO169
Eadon, Michael T., ferreira, Ricardo Melo, Winfree, Seth, Lake, Blue, Cheng, Ying-Hua, Phillips, Carrie L., Parikh, Samir V., Barwinska, Daria, Ferkowicz, Michael J., Sabo, Angela R., Gisch, Debora L., Sutton, Timothy A., Dunn, Ken, Asghari, Mahla, Rovin, Brad H., Kelly, Katherine J., Jain, Sanjay, Dagher, Pierre C., El-Achkar, Tarek M.
Published in Journal of the American Society of Nephrology (01.11.2022)
Published in Journal of the American Society of Nephrology (01.11.2022)
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Journal Article
A Spatially Anchored Transcriptomic Atlas of the Human Kidney Papilla Identifies Significant Immune Injury and Matrix Remodeling in Stone Disease Patients: FR-OR09
Sabo, Angela R., Canela, Victor Hugo, Bowen, William S., ferreira, Ricardo Melo, Barwinska, Daria, Winfree, Seth, Lake, Blue, Cheng, Ying-Hua, LaFavers, Kaice A., Zhang, Kun, Coe, Fredric L., Worcester, Elaine M., Jain, Sanjay, Eadon, Michael T., Williams, James C., El-Achkar, Tarek M.
Published in Journal of the American Society of Nephrology (01.11.2022)
Published in Journal of the American Society of Nephrology (01.11.2022)
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Journal Article