Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA
Herzner, Anna-Maria, Hagmann, Cristina Amparo, Goldeck, Marion, Wolter, Steven, Kübler, Kirsten, Wittmann, Sabine, Gramberg, Thomas, Andreeva, Liudmila, Hopfner, Karl-Peter, Mertens, Christina, Zillinger, Thomas, Jin, Tengchuan, Xiao, Tsan Sam, Bartok, Eva, Coch, Christoph, Ackermann, Damian, Hornung, Veit, Ludwig, Janos, Barchet, Winfried, Hartmann, Gunther, Schlee, Martin
Published in Nature immunology (01.10.2015)
Published in Nature immunology (01.10.2015)
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Journal Article
IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation
Hotter, Dominik, Bosso, Matteo, Jønsson, Kasper L., Krapp, Christian, Stürzel, Christina M., Das, Atze, Littwitz-Salomon, Elisabeth, Berkhout, Ben, Russ, Alina, Wittmann, Sabine, Gramberg, Thomas, Zheng, Yue, Martins, Laura J., Planelles, Vicente, Jakobsen, Martin R., Hahn, Beatrice H., Dittmer, Ulf, Sauter, Daniel, Kirchhoff, Frank
Published in Cell host & microbe (12.06.2019)
Published in Cell host & microbe (12.06.2019)
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Journal Article
A frequent SNP in TRIM5α strongly enhances the innate immune response against LINE-1 elements
Lagisquet, Justine, Conrad, Marcus, Wittmann, Sabine, Volkmann, Bianca, Weissinger, Hannah, Sticht, Heinrich, Gramberg, Thomas
Published in Frontiers in immunology (26.04.2023)
Published in Frontiers in immunology (26.04.2023)
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Journal Article
Attenuation of SARS‐CoV‐2 replication and associated inflammation by concomitant targeting of viral and host cap 2'‐O‐ribose methyltransferases
Bergant, Valter, Yamada, Shintaro, Grass, Vincent, Tsukamoto, Yuta, Lavacca, Teresa, Krey, Karsten, Mühlhofer, Maria‐Teresa, Wittmann, Sabine, Ensser, Armin, Herrmann, Alexandra, vom Hemdt, Anja, Tomita, Yuriko, Matsuyama, Shutoku, Hirokawa, Takatsugu, Huang, Yiqi, Piras, Antonio, Jakwerth, Constanze A, Oelsner, Madlen, Thieme, Susanne, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Kümmerer, Beate M, Stukalov, Alexey, Schmidt‐Weber, Carsten B, Igarashi, Manabu, Gramberg, Thomas, Pichlmair, Andreas, Kato, Hiroki
Published in The EMBO journal (01.09.2022)
Published in The EMBO journal (01.09.2022)
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Journal Article
Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells
Bosso, Matteo, Prelli Bozzo, Caterina, Hotter, Dominik, Volcic, Meta, Stürzel, Christina M, Rammelt, Annika, Ni, Yi, Urban, Stephan, Becker, Miriam, Schelhaas, Mario, Wittmann, Sabine, Christensen, Maria H, Schmidt, Florian I, Gramberg, Thomas, Sparrer, Konstantin M J, Sauter, Daniel, Kirchhoff, Frank
Published in PLoS pathogens (06.08.2020)
Published in PLoS pathogens (06.08.2020)
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Journal Article
Restriction of diverse retroviruses by SAMHD1
Gramberg, Thomas, Kahle, Tanja, Bloch, Nicolin, Wittmann, Sabine, Müllers, Erik, Daddacha, Waaqo, Hofmann, Henning, Kim, Baek, Lindemann, Dirk, Landau, Nathaniel R
Published in Retrovirology (05.03.2013)
Published in Retrovirology (05.03.2013)
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Journal Article
Mouse SAMHD1 Has Antiretroviral Activity and Suppresses a Spontaneous Cell-Intrinsic Antiviral Response
Behrendt, Rayk, Schumann, Tina, Gerbaulet, Alexander, Nguyen, Laura A., Schubert, Nadja, Alexopoulou, Dimitra, Berka, Ursula, Lienenklaus, Stefan, Peschke, Katrin, Gibbert, Kathrin, Wittmann, Sabine, Lindemann, Dirk, Weiss, Siegfried, Dahl, Andreas, Naumann, Ronald, Dittmer, Ulf, Kim, Baek, Mueller, Werner, Gramberg, Thomas, Roers, Axel
Published in Cell reports (Cambridge) (29.08.2013)
Published in Cell reports (Cambridge) (29.08.2013)
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Journal Article
The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation
Herrmann, Alexandra, Wittmann, Sabine, Thomas, Dominique, Shepard, Caitlin N, Kim, Baek, Ferreirós, Nerea, Gramberg, Thomas
Published in Mobile DNA (28.03.2018)
Published in Mobile DNA (28.03.2018)
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Journal Article
A viral kinase counteracts in vivo restriction of murine cytomegalovirus by SAMHD1
Deutschmann, Janina, Schneider, Andrea, Gruska, Iris, Vetter, Barbara, Thomas, Dominique, Kießling, Melissa, Wittmann, Sabine, Herrmann, Alexandra, Schindler, Michael, Milbradt, Jens, Ferreirós, Nerea, Winkler, Thomas H., Wiebusch, Lüder, Gramberg, Thomas
Published in Nature microbiology (01.12.2019)
Published in Nature microbiology (01.12.2019)
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Journal Article
TRIM19/PML Restricts HIV Infection in a Cell Type-Dependent Manner
Kahle, Tanja, Volkmann, Bianca, Eissmann, Kristin, Herrmann, Alexandra, Schmitt, Sven, Wittmann, Sabine, Merkel, Laura, Reuter, Nina, Stamminger, Thomas, Gramberg, Thomas
Published in Viruses (01.01.2016)
Published in Viruses (01.01.2016)
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Journal Article
The T-cell Lymphokine Interleukin-26 Targets Epithelial Cells through the Interleukin-20 Receptor 1 and Interleukin-10 Receptor 2 Chains
Hör, Simon, Pirzer, Heide, Dumoutier, Laure, Bauer, Finn, Wittmann, Sabine, Sticht, Heinrich, Renauld, Jean-Christophe, de Waal Malefyt, René, Fickenscher, Helmut
Published in The Journal of biological chemistry (06.08.2004)
Published in The Journal of biological chemistry (06.08.2004)
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Journal Article
Comparison of colorimeter and different portable food-scanners for non-destructive prediction of lycopene content in tomato fruit
Goisser, Simon, Wittmann, Sabine, Fernandes, Michael, Mempel, Heike, Ulrichs, Christian
Published in Postharvest Biology and Technology (01.09.2020)
Published in Postharvest Biology and Technology (01.09.2020)
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Journal Article
Book Review
Results of a Qualitative Market Research Study Evaluating the Quality of Medical Letters
Fett, Rodegunde, Bruns, Kai, Lischka-Wittmann, Sabine
Published in Drug information journal (01.11.2009)
Published in Drug information journal (01.11.2009)
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Journal Article
Nsp16 shields SARS–CoV‐2 from efficient MDA5 sensing and IFIT1‐mediated restriction
Russ, Alina, Wittmann, Sabine, Tsukamoto, Yuta, Herrmann, Alexandra, Deutschmann, Janina, Lagisquet, Justine, Ensser, Armin, Kato, Hiroki, Gramberg, Thomas
Published in EMBO reports (06.12.2022)
Published in EMBO reports (06.12.2022)
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Journal Article
Human TRIM5α senses and restricts LINE-1 elements
Volkmann, Bianca, Wittmann, Sabine, Lagisquet, Justine, Deutschmann, Janina, Eissmann, Kristin, Ross, James J., Biesinger, Brigitte, Gramberg, Thomas
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2020)
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Journal Article
Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel’s γ-subunit
Sure, Florian, Bertog, Marko, Afonso, Sara, Diakov, Alexei, Rinke, Ralf, Madej, M. Gregor, Wittmann, Sabine, Gramberg, Thomas, Korbmacher, Christoph, Ilyaskin, Alexandr V.
Published in The Journal of biological chemistry (01.06.2022)
Published in The Journal of biological chemistry (01.06.2022)
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Journal Article