Design, Synthesis, Calorimetry, and Crystallographic Analysis of 2-Alkylaminoethyl-1,1-bisphosphonates as Inhibitors of Trypanosoma cruzi Farnesyl Diphosphate Synthase
Aripirala, Srinivas, Szajnman, Sergio H, Jakoncic, Jean, Rodriguez, Juan B, Docampo, Roberto, Gabelli, Sandra B, Amzel, L. Mario
Published in Journal of medicinal chemistry (26.07.2012)
Published in Journal of medicinal chemistry (26.07.2012)
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Design, synthesis and biological evaluation of sulfur-containing 1,1-bisphosphonic acids as antiparasitic agents
Recher, Marion, Barboza, Alejandro P., Li, Zhu-Hong, Galizzi, Melina, Ferrer-Casal, Mariana, Szajnman, Sergio H., Docampo, Roberto, Moreno, Silvia N.J., Rodriguez, Juan B.
Published in European journal of medicinal chemistry (01.02.2013)
Published in European journal of medicinal chemistry (01.02.2013)
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Antiparasitic Activity of Sulfur- and Fluorine-Containing Bisphosphonates against Trypanosomatids and Apicomplexan Parasites
Galaka, Tamila, Ferrer Casal, Mariana, Storey, Melissa, Li, Catherine, Chao, María N, Szajnman, Sergio H, Docampo, Roberto, Moreno, Silvia N J, Rodriguez, Juan B
Published in Molecules (Basel, Switzerland) (01.01.2017)
Published in Molecules (Basel, Switzerland) (01.01.2017)
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Synthesis and biological evaluation of new 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase
Rosso, Valeria S., Szajnman, Sergio H., Malayil, Leena, Galizzi, Melina, Moreno, Silvia N.J., Docampo, Roberto, Rodriguez, Juan B.
Published in Bioorganic & medicinal chemistry (01.04.2011)
Published in Bioorganic & medicinal chemistry (01.04.2011)
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2-Alkylaminoethyl-1,1-Bisphosphonic Acids Are Potent Inhibitors of the Enzymatic Activity of Trypanosoma cruzi Squalene Synthase
Rodrígues-Poveda, Carlos A, González-Pacanowska, Dolores, Szajnman, Sergio H, Rodríguez, Juan B
Published in Antimicrobial Agents and Chemotherapy (01.08.2012)
Published in Antimicrobial Agents and Chemotherapy (01.08.2012)
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An updated review of chemical compounds with anti-Toxoplasma gondii activity
Rodriguez, Juan B., Szajnman, Sergio H.
Published in European journal of medicinal chemistry (15.12.2023)
Published in European journal of medicinal chemistry (15.12.2023)
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Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase
Szajnman, Sergio H., Ravaschino, Esteban L., Docampo, Roberto, Rodriguez, Juan B.
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
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Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase
Szajnman, Sergio H., Garcı´a Liñares, Guadalupe E., Li, Zhu-Hong, Jiang, Cuiying, Galizzi, Melina, Bontempi, Esteban J., Ferella, Marcela, Moreno, Silvia N.J., Docampo, Roberto, Rodriguez, Juan B.
Published in Bioorganic & medicinal chemistry (15.03.2008)
Published in Bioorganic & medicinal chemistry (15.03.2008)
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Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase
Szajnman, Sergio H., Montalvetti, Andrea, Wang, Youhong, Docampo, Roberto, Rodriguez, Juan B.
Published in Bioorganic & medicinal chemistry letters (06.10.2003)
Published in Bioorganic & medicinal chemistry letters (06.10.2003)
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Synthesis and biological evaluation of 1-alkylaminomethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii
Galaka, Tamila, Falcone, Bruno N., Li, Catherine, Szajnman, Sergio H., Moreno, Silvia N.J., Docampo, Roberto, Rodriguez, Juan B.
Published in Bioorganic & medicinal chemistry (15.08.2019)
Published in Bioorganic & medicinal chemistry (15.08.2019)
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Selenium-containing analogues of WC-9 are extremely potent inhibitors of Trypanosoma cruzi proliferation
Chao, María N., Storey, Melissa, Li, Catherine, Rodríguez, Maricel G., Di Salvo, Florencia, Szajnman, Sergio H., Moreno, Silvia N.J., Docampo, Roberto, Rodriguez, Juan B.
Published in Bioorganic & medicinal chemistry (15.12.2017)
Published in Bioorganic & medicinal chemistry (15.12.2017)
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Approaches for Designing new Potent Inhibitors of Farnesyl Pyrophosphate Synthase
Rodriguez, Juan B, Falcone, Bruno N, Szajnman, Sergio H
Published in Expert opinion on drug discovery (03.03.2016)
Published in Expert opinion on drug discovery (03.03.2016)
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Detection and treatment of Trypanosoma cruzi: a patent review (2011-2015)
Rodriguez, Juan B, Falcone, Bruno N, Szajnman, Sergio H
Published in Expert opinion on therapeutic patents (01.09.2016)
Published in Expert opinion on therapeutic patents (01.09.2016)
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In Vitro and In Vivo Activities of Sulfur-Containing Linear Bisphosphonates against Apicomplexan Parasites
Szajnman, Sergio H, Galaka, Tamila, Li, Zhu-Hong, Li, Catherine, Howell, Nathan M, Chao, María N, Striepen, Boris, Muralidharan, Vasant, Moreno, Silvia N J, Rodriguez, Juan B
Published in Antimicrobial agents and chemotherapy (01.02.2017)
Published in Antimicrobial agents and chemotherapy (01.02.2017)
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New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase
Ferrer-Casal, Mariana, Li, Catherine, Galizzi, Melina, Stortz, Carlos A., Szajnman, Sergio H., Docampo, Roberto, Moreno, Silvia N.J., Rodriguez, Juan B.
Published in Bioorganic & medicinal chemistry (01.01.2014)
Published in Bioorganic & medicinal chemistry (01.01.2014)
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1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase
Szajnman, Sergio H., Rosso, Valeria S., Malayil, Leena, Smith, Alyssa, Moreno, Silvia N. J., Docampo, Roberto, Rodriguez, Juan B.
Published in Organic & biomolecular chemistry (21.02.2012)
Published in Organic & biomolecular chemistry (21.02.2012)
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Activity of Fluorine-Containing Analogues of WC-9 and Structurally Related Analogues against Two Intracellular Parasites: Trypanosoma cruzi and Toxoplasma gondii
Chao, María N., Li, Catherine, Storey, Melissa, Falcone, Bruno N., Szajnman, Sergio H., Bonesi, Sergio M., Docampo, Roberto, Moreno, Silvia N. J., Rodriguez, Juan B.
Published in ChemMedChem (16.12.2016)
Published in ChemMedChem (16.12.2016)
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