Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment
Kfoury, Youmna, Baryawno, Ninib, Severe, Nicolas, Mei, Shenglin, Gustafsson, Karin, Hirz, Taghreed, Brouse, Thomas, Scadden, Elizabeth W., Igolkina, Anna A., Kokkaliaris, Konstantinos, Choi, Bryan D., Barkas, Nikolas, Randolph, Mark A., Shin, John H., Saylor, Philip J., Scadden, David T., Sykes, David B., Kharchenko, Peter V.
Published in Cancer cell (08.11.2021)
Published in Cancer cell (08.11.2021)
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Journal Article
Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin
Palchaudhuri, Rahul, Saez, Borja, Hoggatt, Jonathan, Schajnovitz, Amir, Sykes, David B, Tate, Tiffany A, Czechowicz, Agnieszka, Kfoury, Youmna, Ruchika, FNU, Rossi, Derrick J, Verdine, Gregory L, Mansour, Michael K, Scadden, David T
Published in Nature biotechnology (01.07.2016)
Published in Nature biotechnology (01.07.2016)
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Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53
Yoon, Kyoung Wan, Byun, Sanguine, Kwon, Eunjeong, Hwang, So-Young, Chu, Kiki, Hiraki, Masatsugu, Jo, Seung-Hee, Weins, Astrid, Hakroush, Samy, Cebulla, Angelika, Sykes, David B., Greka, Anna, Mundel, Peter, Fisher, David E., Mandinova, Anna, Lee, Sam W.
Published in Science (American Association for the Advancement of Science) (31.07.2015)
Published in Science (American Association for the Advancement of Science) (31.07.2015)
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Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses
Hirz, Taghreed, Mei, Shenglin, Sarkar, Hirak, Kfoury, Youmna, Wu, Shulin, Verhoeven, Bronte M., Subtelny, Alexander O., Zlatev, Dimitar V., Wszolek, Matthew W., Salari, Keyan, Murray, Evan, Chen, Fei, Macosko, Evan Z., Wu, Chin-Lee, Scadden, David T., Dahl, Douglas M., Baryawno, Ninib, Saylor, Philip J., Kharchenko, Peter V., Sykes, David B.
Published in Nature communications (07.02.2023)
Published in Nature communications (07.02.2023)
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Journal Article
Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney
Simic, Petra, Kim, Wondong, Zhou, Wen, Pierce, Kerry A, Chang, Wenhan, Sykes, David B, Aziz, Najihah B, Elmariah, Sammy, Ngo, Debby, Pajevic, Paola Divieti, Govea, Nicolas, Kestenbaum, Bryan R, de Boer, Ian H, Cheng, Zhiqiang, Christov, Marta, Chun, Jerold, Leaf, David E, Waikar, Sushrut S, Tager, Andrew M, Gerszten, Robert E, Thadhani, Ravi I, Clish, Clary B, Jüppner, Harald, Wein, Marc N, Rhee, Eugene P
Published in The Journal of clinical investigation (01.03.2020)
Published in The Journal of clinical investigation (01.03.2020)
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Journal Article
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β‐catenin
Simic, Petra, Zainabadi, Kayvan, Bell, Eric, Sykes, David B., Saez, Borja, Lotinun, Sutada, Baron, Roland, Scadden, David, Schipani, Ernestina, Guarente, Leonard
Published in EMBO molecular medicine (01.03.2013)
Published in EMBO molecular medicine (01.03.2013)
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Journal Article
Severe autoimmune hemolytic anemia following receipt of SARS‐CoV‐2 mRNA vaccine
Gadi, Sanjay R. V., Brunker, Patricia A. R., Al‐Samkari, Hanny, Sykes, David B., Saff, Rebecca R., Lo, Janet, Bendapudi, Pavan, Leaf, David E., Leaf, Rebecca Karp
Published in Transfusion (Philadelphia, Pa.) (01.11.2021)
Published in Transfusion (Philadelphia, Pa.) (01.11.2021)
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Inhibiting the biogenesis of myeloid-derived suppressor cells enhances immunotherapy efficacy against mammary tumor progression
Colligan, Sean H, Amitrano, Andrea M, Zollo, Robert A, Peresie, Jennifer, Kramer, Elliot D, Morreale, Brian, Barbi, Joseph, Singh, Prashant K, Yu, Han, Wang, Jianmin, Opyrchal, Mateusz, Sykes, David B, Nemeth, Michael J, Abrams, Scott I
Published in The Journal of clinical investigation (01.12.2022)
Published in The Journal of clinical investigation (01.12.2022)
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Journal Article
KAT6A and ENL Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs
Yan, Fangxue, Li, Jinyang, Milosevic, Jelena, Petroni, Ricardo, Liu, Suying, Shi, Zhennan, Yuan, Salina, Reynaga, Janice M, Qi, Yuwei, Rico, Joshua, Yu, Sixiang, Liu, Yiman, Rokudai, Susumu, Palmisiano, Neil, Meyer, Sara E, Sung, Pamela J, Wan, Liling, Lan, Fei, Garcia, Benjamin A, Stanger, Ben Z, Sykes, David B, Blanco, M Andrés
Published in Cancer discovery (01.03.2022)
Published in Cancer discovery (01.03.2022)
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Journal Article
Modulating Cell Fate as a Therapeutic Strategy
Lin, Brian, Srikanth, Priya, Castle, Alison C., Nigwekar, Sagar, Malhotra, Rajeev, Galloway, Jenna L., Sykes, David B., Rajagopal, Jayaraj
Published in Cell stem cell (06.09.2018)
Published in Cell stem cell (06.09.2018)
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Journal Article
A transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma
Alchahin, Adele M., Mei, Shenglin, Tsea, Ioanna, Hirz, Taghreed, Kfoury, Youmna, Dahl, Douglas, Wu, Chin-Lee, Subtelny, Alexander O., Wu, Shulin, Scadden, David T., Shin, John H., Saylor, Philip J., Sykes, David B., Kharchenko, Peter V., Baryawno, Ninib
Published in Nature communications (30.09.2022)
Published in Nature communications (30.09.2022)
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Journal Article
An unappreciated role for neutrophil-DC hybrids in immunity to invasive fungal infections
Fites, J Scott, Gui, Michael, Kernien, John F, Negoro, Paige, Dagher, Zeina, Sykes, David B, Nett, Jeniel E, Mansour, Michael K, Klein, Bruce S
Published in PLoS pathogens (01.05.2018)
Published in PLoS pathogens (01.05.2018)
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Journal Article
Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities
Petenkova, Anastasiia, Auger, Shelby A., Lamb, Jeffrey, Quellier, Daisy, Carter, Cody, To, On Tak, Milosevic, Jelena, Barghout, Rana, Kugadas, Abirami, Lu, Xiaoxiao, Geddes-McAlister, Jennifer, Fichorova, Raina, Sykes, David B., Distefano, Mark D., Gadjeva, Mihaela
Published in Nature communications (13.05.2023)
Published in Nature communications (13.05.2023)
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Journal Article
Chromatin accessibility promotes hematopoietic and leukemia stem cell activity
Cabal-Hierro, Lucia, van Galen, Peter, Prado, Miguel A., Higby, Kelly J., Togami, Katsuhiro, Mowery, Cody T., Paulo, Joao A., Xie, Yingtian, Cejas, Paloma, Furusawa, Takashi, Bustin, Michael, Long, Henry W., Sykes, David B., Gygi, Steven P., Finley, Daniel, Bernstein, Bradley E., Lane, Andrew A.
Published in Nature communications (16.03.2020)
Published in Nature communications (16.03.2020)
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Journal Article
mTORC1 links pathology in experimental models of Still’s disease and macrophage activation syndrome
Huang, Zhengping, You, Xiaomeng, Chen, Liang, Du, Yan, Brodeur, Kailey, Jee, Hyuk, Wang, Qiang, Linder, Grace, Darbousset, Roxane, Cunin, Pierre, Chang, Margaret H., Wactor, Alexandra, Wauford, Brian M., Todd, Marc J. C., Wei, Kevin, Li, Ying, Levescot, Anais, Iwakura, Yoichiro, Pascual, Virginia, Baldwin, Nicole E., Quartier, Pierre, Li, Tianwang, Gianatasio, Maria T., Hasserjian, Robert P., Henderson, Lauren A., Sykes, David B., Mellins, Elizabeth D., Canna, Scott W., Charles, Julia F., Nigrovic, Peter A., Lee, Pui Y.
Published in Nature communications (28.11.2022)
Published in Nature communications (28.11.2022)
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Journal Article
The Successful Use of Apixaban in Dialysis Patients with Calciphylaxis Who Require Anticoagulation: A Retrospective Analysis
Garza-Mayers, Anna C, Shah, Radhika, Sykes, David B, Nigwekar, Sagar U, Kroshinsky, Daniela
Published in American journal of nephrology (01.01.2018)
Published in American journal of nephrology (01.01.2018)
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Journal Article
Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity
Franklin, Reuben, Guo, Yiming, He, Shiyang, Chen, Meijuan, Ji, Fei, Zhou, Xinyue, Frankhouser, David, Do, Brian T., Chiem, Carmen, Jang, Mihyun, Blanco, M. Andres, Vander Heiden, Matthew G., Rockne, Russell C., Ninova, Maria, Sykes, David B., Hochedlinger, Konrad, Lu, Rui, Sadreyev, Ruslan I., Murn, Jernej, Volk, Andrew, Cheloufi, Sihem
Published in Nature communications (29.04.2022)
Published in Nature communications (29.04.2022)
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Journal Article
SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst
Nguyen, Giang T, Shaban, Lamyaa, Mack, Matthias, Swanson, Kenneth D, Bunnell, Stephen C, Sykes, David B, Mecsas, Joan
Published in eLife (30.04.2020)
Published in eLife (30.04.2020)
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Journal Article
The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG
Kugler, Eitan, Madiwale, Shreyas, Yong, Darren, Thoms, Julie A. I., Birger, Yehudit, Sykes, David B., Schmoellerl, Johannes, Drakul, Aneta, Priebe, Valdemar, Yassin, Muhammad, Aqaqe, Nasma, Rein, Avigail, Fishman, Hila, Geron, Ifat, Chen, Chun-Wei, Raught, Brian, Liu, Qiao, Ogana, Heather, Liedke, Elisabeth, Bourquin, Jean-Pierre, Zuber, Johannes, Milyavsky, Michael, Pimanda, John, Privé, Gilbert G., Izraeli, Shai
Published in Nature communications (21.09.2023)
Published in Nature communications (21.09.2023)
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