Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures
Zaitsev, Konstantin, Bambouskova, Monika, Swain, Amanda, Artyomov, Maxim N
Published in Nature communications (17.05.2019)
Published in Nature communications (17.05.2019)
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Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease
Zhou, Yingyue, Song, Wilbur M, Andhey, Prabhakar S, Swain, Amanda, Levy, Tyler, Miller, Kelly R, Poliani, Pietro L, Cominelli, Manuela, Grover, Shikha, Gilfillan, Susan, Cella, Marina, Ulland, Tyler K, Zaitsev, Konstantin, Miyashita, Akinori, Ikeuchi, Takeshi, Sainouchi, Makoto, Kakita, Akiyoshi, Bennett, David A, Schneider, Julie A, Nichols, Michael R, Beausoleil, Sean A, Ulrich, Jason D, Holtzman, David M, Artyomov, Maxim N, Colonna, Marco
Published in Nature medicine (01.01.2020)
Published in Nature medicine (01.01.2020)
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Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders
Brioschi, Simone, Wang, Wei-Le, Peng, Vincent, Wang, Meng, Shchukina, Irina, Greenberg, Zev J, Bando, Jennifer K, Jaeger, Natalia, Czepielewski, Rafael S, Swain, Amanda, Mogilenko, Denis A, Beatty, Wandy L, Bayguinov, Peter, Fitzpatrick, James A J, Schuettpelz, Laura G, Fronick, Catrina C, Smirnov, Igor, Kipnis, Jonathan, Shapiro, Virginia S, Wu, Gregory F, Gilfillan, Susan, Cella, Marina, Artyomov, Maxim N, Kleinstein, Steven H, Colonna, Marco
Published in Science (American Association for the Advancement of Science) (23.07.2021)
Published in Science (American Association for the Advancement of Science) (23.07.2021)
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Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance
Pettitt, Stephen J, Krastev, Dragomir B, Brandsma, Inger, Dréan, Amy, Song, Feifei, Aleksandrov, Radoslav, Harrell, Maria I, Menon, Malini, Brough, Rachel, Campbell, James, Frankum, Jessica, Ranes, Michael, Pemberton, Helen N, Rafiq, Rumana, Fenwick, Kerry, Swain, Amanda, Guettler, Sebastian, Lee, Jung-Min, Swisher, Elizabeth M, Stoynov, Stoyno, Yusa, Kosuke, Ashworth, Alan, Lord, Christopher J
Published in Nature communications (10.05.2018)
Published in Nature communications (10.05.2018)
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Targeting the p300/CBP Axis in Lethal Prostate Cancer
Welti, Jonathan, Sharp, Adam, Brooks, Nigel, Yuan, Wei, McNair, Christopher, Chand, Saswati N, Pal, Abhijit, Figueiredo, Ines, Riisnaes, Ruth, Gurel, Bora, Rekowski, Jan, Bogdan, Denisa, West, William, Young, Barbara, Raja, Meera, Prosser, Amy, Lane, Jordan, Thomson, Stuart, Worthington, Jenny, Onions, Stuart, Shannon, Jonathan, Paoletta, Silvia, Brown, Richard, Smyth, Don, Harbottle, Gareth W, Gil, Veronica S, Miranda, Susana, Crespo, Mateus, Ferreira, Ana, Pereira, Rita, Tunariu, Nina, Carreira, Suzanne, Neeb, Antje J, Ning, Jian, Swain, Amanda, Taddei, David, Schiewer, Matthew J, Knudsen, Karen E, Pegg, Neil, de Bono, Johann S
Published in Cancer discovery (01.05.2021)
Published in Cancer discovery (01.05.2021)
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Itaconate confers tolerance to late NLRP3 inflammasome activation
Bambouskova, Monika, Potuckova, Lucie, Paulenda, Tomas, Kerndl, Martina, Mogilenko, Denis A., Lizotte, Kate, Swain, Amanda, Hayes, Sebastian, Sheldon, Ryan D., Kim, Hyeryun, Kapadnis, Unnati, Ellis, Abigail E., Isaguirre, Christine, Burdess, Samantha, Laha, Anwesha, Amarasinghe, Gaya K., Chubukov, Victor, Roddy, Thomas P., Diamond, Michael S., Jones, Russell G., Simons, Donald M., Artyomov, Maxim N.
Published in Cell reports (Cambridge) (09.03.2021)
Published in Cell reports (Cambridge) (09.03.2021)
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Human early-onset dementia caused by DAP12 deficiency reveals a unique signature of dysregulated microglia
Zhou, Yingyue, Tada, Mari, Cai, Zhangying, Andhey, Prabhakar S, Swain, Amanda, Miller, Kelly R, Gilfillan, Susan, Artyomov, Maxim N, Takao, Masaki, Kakita, Akiyoshi, Colonna, Marco
Published in Nature immunology (01.03.2023)
Published in Nature immunology (01.03.2023)
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Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC)
Welti, Jonathan, Sharp, Adam, Yuan, Wei, Dolling, David, Nava Rodrigues, Daniel, Figueiredo, Ines, Gil, Veronica, Neeb, Antje, Clarke, Matthew, Seed, George, Crespo, Mateus, Sumanasuriya, Semini, Ning, Jian, Knight, Eleanor, Francis, Jeffrey C, Hughes, Ashley, Halsey, Wendy S, Paschalis, Alec, Mani, Ram S, Raj, Ganesh V, Plymate, Stephen R, Carreira, Suzanne, Boysen, Gunther, Chinnaiyan, Arul M, Swain, Amanda, de Bono, Johann S
Published in Clinical cancer research (01.07.2018)
Published in Clinical cancer research (01.07.2018)
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High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial
Pearson, Alex, Smyth, Elizabeth, Babina, Irina S, Herrera-Abreu, Maria Teresa, Tarazona, Noelia, Peckitt, Clare, Kilgour, Elaine, Smith, Neil R, Geh, Catherine, Rooney, Claire, Cutts, Ros, Campbell, James, Ning, Jian, Fenwick, Kerry, Swain, Amanda, Brown, Gina, Chua, Sue, Thomas, Anne, Johnston, Stephen R D, Ajaz, Mazhar, Sumpter, Katherine, Gillbanks, Angela, Watkins, David, Chau, Ian, Popat, Sanjay, Cunningham, David, Turner, Nicholas C
Published in Cancer discovery (01.08.2016)
Published in Cancer discovery (01.08.2016)
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Intestinal cell diversity and treatment responses in a parasitic nematode at single cell resolution
Tyagi, Rahul, Rosa, Bruce A, Swain, Amanda, Artyomov, Maxim N, Jasmer, Douglas P, Mitreva, Makedonka
Published in BMC genomics (04.04.2024)
Published in BMC genomics (04.04.2024)
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Journal Article
HER3 Is an Actionable Target in Advanced Prostate Cancer
Gil, Veronica, Miranda, Susana, Riisnaes, Ruth, Gurel, Bora, D'Ambrosio, Mariantonietta, Vasciaveo, Alessandro, Crespo, Mateus, Ferreira, Ana, Brina, Daniela, Troiani, Martina, Sharp, Adam, Sheehan, Beshara, Christova, Rossitza, Seed, George, Figueiredo, Ines, Lambros, Maryou, Dolling, David, Rekowski, Jan, Alajati, Abdullah, Clarke, Matthew, Pereira, Rita, Flohr, Penny, Fowler, Gemma, Boysen, Gunther, Sumanasuriya, Semini, Bianchini, Diletta, Rescigno, Pasquale, Aversa, Caterina, Tunariu, Nina, Guo, Christina, Paschalis, Alec, Bertan, Claudia, Buroni, Lorenzo, Ning, Jian, Carreira, Suzanne, Workman, Paul, Swain, Amanda, Califano, Andrea, Shen, Michael M, Alimonti, Andrea, Neeb, Antje, Welti, Jonathan, Yuan, Wei, de Bono, Johann
Published in Cancer research (Chicago, Ill.) (15.12.2021)
Published in Cancer research (Chicago, Ill.) (15.12.2021)
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Myeloid cell interferon responses correlate with clearance of SARS-CoV-2
Singh, Dhiraj K, Aladyeva, Ekaterina, Das, Shibali, Singh, Bindu, Esaulova, Ekaterina, Swain, Amanda, Ahmed, Mushtaq, Cole, Journey, Moodley, Chivonne, Mehra, Smriti, Schlesinger, Larry S, Artyomov, Maxim N, Khader, Shabaana A, Kaushal, Deepak
Published in Nature communications (03.02.2022)
Published in Nature communications (03.02.2022)
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β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma
Francis, Jeffrey C, Thomsen, Martin K, Taketo, Makoto M, Swain, Amanda
Published in PLoS genetics (01.01.2013)
Published in PLoS genetics (01.01.2013)
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Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination
Hou, Jinchao, Zhou, Yingyue, Cai, Zhangying, Terekhova, Marina, Swain, Amanda, Andhey, Prabhakar S., Guimaraes, Rafaela M., Ulezko Antonova, Alina, Qiu, Tian, Sviben, Sanja, Strout, Gregory, Fitzpatrick, James A.J., Chen, Yun, Gilfillan, Susan, Kim, Do-Hyun, Van Dyken, Steven J., Artyomov, Maxim N., Colonna, Marco
Published in Cell reports (Cambridge) (25.04.2023)
Published in Cell reports (Cambridge) (25.04.2023)
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Drosophila TDP-43 RNA-Binding Protein Facilitates Association of Sister Chromatid Cohesion Proteins with Genes, Enhancers and Polycomb Response Elements
Swain, Amanda, Misulovin, Ziva, Pherson, Michelle, Gause, Maria, Mihindukulasuriya, Kathie, Rickels, Ryan A, Shilatifard, Ali, Dorsett, Dale
Published in PLoS genetics (23.09.2016)
Published in PLoS genetics (23.09.2016)
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Wnt4 participates in the formation of vertebrate neuromuscular junction
Strochlic, Laure, Falk, Julien, Goillot, Evelyne, Sigoillot, Séverine, Bourgeois, Francine, Delers, Perrine, Rouvière, Jérôme, Swain, Amanda, Castellani, Valérie, Schaeffer, Laurent, Legay, Claire
Published in PloS one (12.01.2012)
Published in PloS one (12.01.2012)
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Drawing for Visual Communication in Medicine: A Novel Pilot Course for Senior Medical Students
Card, Elizabeth B., Lejbman, Julian, Trueblood, Eo, Bennett, Brittany C., Dunham, Brian P., Swain, Amanda J., Delisser, Horace M.
Published in Journal of surgical education (01.03.2022)
Published in Journal of surgical education (01.03.2022)
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Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage
Val, Pierre, Martinez-Barbera, Juan-Pedro, Swain, Amanda
Published in Development (Cambridge) (15.06.2007)
Published in Development (Cambridge) (15.06.2007)
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