BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression
Zhu, Hengrui, Bengsch, Fee, Svoronos, Nikolaos, Rutkowski, Melanie R., Bitler, Benjamin G., Allegrezza, Michael J., Yokoyama, Yuhki, Kossenkov, Andrew V., Bradner, James E., Conejo-Garcia, Jose R., Zhang, Rugang
Published in Cell reports (Cambridge) (13.09.2016)
Published in Cell reports (Cambridge) (13.09.2016)
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Journal Article
Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells
Svoronos, Nikolaos, Perales-Puchalt, Alfredo, Allegrezza, Michael J, Rutkowski, Melanie R, Payne, Kyle K, Tesone, Amelia J, Nguyen, Jenny M, Curiel, Tyler J, Cadungog, Mark G, Singhal, Sunil, Eruslanov, Evgeniy B, Zhang, Paul, Tchou, Julia, Zhang, Rugang, Conejo-Garcia, Jose R
Published in Cancer discovery (01.01.2017)
Published in Cancer discovery (01.01.2017)
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Journal Article
Frontline Science: Microbiota reconstitution restores intestinal integrity after cisplatin therapy
Perales‐Puchalt, Alfredo, Perez‐Sanz, Jairo, Payne, Kyle K, Svoronos, Nikolaos, Allegrezza, Michael J., Chaurio, Ricardo A., Anadon, Carmen, Calmette, Joseph, Biswas, Subir, Mine, Jessica A., Costich, Tara Lee, Nickels, Logan, Wickramasinghe, Jayamanna, Rutkowski, Melanie R., Conejo‐Garcia, Jose R.
Published in Journal of leukocyte biology (01.05.2018)
Published in Journal of leukocyte biology (01.05.2018)
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Journal Article
Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic Target
Perales-Puchalt, Alfredo, Svoronos, Nikolaos, Rutkowski, Melanie R, Allegrezza, Michael J, Tesone, Amelia J, Payne, Kyle K, Wickramasinghe, Jayamanna, Nguyen, Jenny M, O'Brien, Shane W, Gumireddy, Kiranmai, Huang, Qihong, Cadungog, Mark G, Connolly, Denise C, Tchou, Julia, Curiel, Tyler J, Conejo-Garcia, Jose R
Published in Clinical cancer research (15.01.2017)
Published in Clinical cancer research (15.01.2017)
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Journal Article
Satb1 Overexpression Drives Tumor-Promoting Activities in Cancer-Associated Dendritic Cells
Tesone, Amelia J., Rutkowski, Melanie R., Brencicova, Eva, Svoronos, Nikolaos, Perales-Puchalt, Alfredo, Stephen, Tom L., Allegrezza, Michael J., Payne, Kyle K., Nguyen, Jenny M., Wickramasinghe, Jayamanna, Tchou, Julia, Borowsky, Mark E., Rabinovich, Gabriel A., Kossenkov, Andrew V., Conejo-Garcia, Jose R.
Published in Cell reports (Cambridge) (23.02.2016)
Published in Cell reports (Cambridge) (23.02.2016)
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Journal Article
IL-33 delays metastatic peritoneal cancer progression inducing an allergic microenvironment
Perales-Puchalt, Alfredo, Svoronos, Nikolaos, Villarreal, Daniel O., Zankharia, Urvi, Reuschel, Emma, Wojtak, Krzysztof, Payne, Kyle K., Duperret, Elizabeth K., Muthumani, Kar, Conejo-Garcia, Jose R., Weiner, David B.
Published in Oncoimmunology (01.01.2019)
Published in Oncoimmunology (01.01.2019)
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Journal Article
Philadelphia chromosome‐like B‐acute lymphoblastic leukemia and disseminated juvenile xanthogranulomatosis with shared KRAS mutation
Cheng, Jinjun, Svoronos, Nikolaos, Pan, Miao, Smith, Shelby, Vatsayan, Anant, Jacobsohn, David, Wistinghausen, Birte
Published in Pediatric blood & cancer (01.06.2024)
Published in Pediatric blood & cancer (01.06.2024)
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Journal Article
Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations
Kugel, 3rd, Curtis H, Douglass, Stephen M, Webster, Marie R, Kaur, Amanpreet, Liu, Qin, Yin, Xiangfan, Weiss, Sarah A, Darvishian, Farbod, Al-Rohil, Rami N, Ndoye, Abibatou, Behera, Reeti, Alicea, Gretchen M, Ecker, Brett L, Fane, Mitchell, Allegrezza, Michael J, Svoronos, Nikolaos, Kumar, Vinit, Wang, Daniel Y, Somasundaram, Rajasekharan, Hu-Lieskovan, Siwen, Ozgun, Alpaslan, Herlyn, Meenhard, Conejo-Garcia, Jose R, Gabrilovich, Dmitry, Stone, Erica L, Nowicki, Theodore S, Sosman, Jeffrey, Rai, Rajat, Carlino, Matteo S, Long, Georgina V, Marais, Richard, Ribas, Antoni, Eroglu, Zeynep, Davies, Michael A, Schilling, Bastian, Schadendorf, Dirk, Xu, Wei, Amaravadi, Ravi K, Menzies, Alexander M, McQuade, Jennifer L, Johnson, Douglas B, Osman, Iman, Weeraratna, Ashani T
Published in Clinical cancer research (01.11.2018)
Published in Clinical cancer research (01.11.2018)
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Journal Article
Microbially Driven TLR5-Dependent Signaling Governs Distal Malignant Progression through Tumor-Promoting Inflammation
Rutkowski, Melanie R., Stephen, Tom L., Svoronos, Nikolaos, Allegrezza, Michael J., Tesone, Amelia J., Perales-Puchalt, Alfredo, Brencicova, Eva, Escovar-Fadul, Ximena, Nguyen, Jenny M., Cadungog, Mark G., Zhang, Rugang, Salatino, Mariana, Tchou, Julia, Rabinovich, Gabriel A., Conejo-Garcia, Jose R.
Published in Cancer cell (12.01.2015)
Published in Cancer cell (12.01.2015)
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Journal Article
A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside
CHIANG, Cheryl Lai-Lai, KANDALAFT, Lana E, LEVINE, Bruce L, KALOS, Michael, CZERNIECKI, Brian J, TORIGIAN, Drew A, POWELL, Daniel J, MICK, Rosemarie, COUKOS, George, TANYI, Janos, HAGEMANN, Andrea R, MOTZ, Gregory T, SVORONOS, Nikolaos, MONTONE, Kathleen, MANTIA-SMALDONE, Gina M, SMITH, Lori, NISENBAUM, Harvey L
Published in Clinical cancer research (01.09.2013)
Published in Clinical cancer research (01.09.2013)
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Journal Article
Improved renal ischemia tolerance in females influences kidney transplantation outcomes
Aufhauser, Jr, David D, Wang, Zhonglin, Murken, Douglas R, Bhatti, Tricia R, Wang, Yanfeng, Ge, Guanghui, Redfield, 3rd, Robert R, Abt, Peter L, Wang, Liqing, Svoronos, Nikolaos, Thomasson, Arwin, Reese, Peter P, Hancock, Wayne W, Levine, Matthew H
Published in The Journal of clinical investigation (01.05.2016)
Published in The Journal of clinical investigation (01.05.2016)
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Journal Article
Transforming Growth Factor β-Mediated Suppression of Antitumor T Cells Requires FoxP1 Transcription Factor Expression
Stephen, Tom L., Rutkowski, Melanie R., Allegrezza, Michael J., Perales-Puchalt, Alfredo, Tesone, Amelia J., Svoronos, Nikolaos, Nguyen, Jenny M., Sarmin, Fahmida, Borowsky, Mark E., Tchou, Julia, Conejo-Garcia, Jose R.
Published in Immunity (Cambridge, Mass.) (18.09.2014)
Published in Immunity (Cambridge, Mass.) (18.09.2014)
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Journal Article
Trametinib Drives T-cell-Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis
Allegrezza, Michael J, Rutkowski, Melanie R, Stephen, Tom L, Svoronos, Nikolaos, Perales-Puchalt, Alfredo, Nguyen, Jenny M, Payne, Kyle K, Singhal, Sunil, Eruslanov, Evgeniy B, Tchou, Julia, Conejo-Garcia, Jose R
Published in Cancer research (Chicago, Ill.) (01.11.2016)
Published in Cancer research (Chicago, Ill.) (01.11.2016)
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Journal Article
The efficacy and the risk of immunogenicity of FIX Padua (R338L) in hemophilia B dogs treated by AAV muscle gene therapy
Finn, Jonathan D., Nichols, Timothy C., Svoronos, Nikolaos, Merricks, Elizabeth P., Bellenger, Dwight A., Zhou, Shangshen, Simioni, Paolo, High, Katherine A., Arruda, Valder R.
Published in Blood (29.11.2012)
Published in Blood (29.11.2012)
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Journal Article
MEK inhibition by trametinib impairs the mobilization of monocytic MDSCs to facilitate anti-tumor T cell immunity
Allegrezza, Michael, Svoronos, Nikolaos, Perales-Puchalt, Alfredo, Payne, Kyle K, Nguyen, Jenny, Conejo-Garcia, Jose R
Published in The Journal of immunology (1950) (01.05.2016)
Published in The Journal of immunology (1950) (01.05.2016)
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Journal Article
Polymorphic UHRF1BP1 drives superior anti-tumor immunity in ovarian cancer
Payne, Kyle K., Svoronos, Nikolaos, Chaurio, Ricardo A., Sanz, Jairo Perez, Anadon, Carmen, Calmette, Joseph, Biswas, Subir, Costich, Tara Lee, Mine, Jessica, Conejo-Garcia, Jose R.
Published in The Journal of immunology (1950) (01.05.2018)
Published in The Journal of immunology (1950) (01.05.2018)
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Journal Article
Satb1 deficiency licenses TFH-differentiation
Chaurio Gonzalez, Ricardo A, Biswas, Subir, Payne, Kyle K., Galindo, Carmen Maria Anadon, Costich, Tara Lee, Perales-Puchalt, Alfredo, Perez-Sanz, Jairo, Harro, Carly M, Mine, Jessica A, Allegrezza, Michael J, Svoronos, Nikolaos, Kroeger, Jodi, Robinson, John, Conejo-Garcia, Jose R
Published in The Journal of immunology (1950) (01.05.2019)
Published in The Journal of immunology (1950) (01.05.2019)
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Journal Article
Abstract AP31: TARGETING PD–L1/PD1 PATHWAY THROUGH BET PROTEIN INHIBITION IN EPITHELIAL OVARIAN CANCER
Zhu, Hengrui, Bengsch, Fee, Svoronos, Nikolaos, Rutkowski, Melanie R., Bitler, Benjamin G., Allegrezza, Michael J., Yokoyama, Yuhki, Bradner, James E., Conejo-Garcia, Jose R., Zhang, Rugang
Published in Clinical cancer research (01.06.2017)
Published in Clinical cancer research (01.06.2017)
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