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Acute transcutaneous auricular vagus nerve stimulation modulates presynaptic SV2A density in healthy rat brain: An in vivo microPET study
Binda, Karina H., Real, Caroline C., Simonsen, Mette T., Grove, Ebbe K., Bender, Dirk, Gjedde, Albert, Brooks, David J., Landau, Anne M.
Published in Psychophysiology (01.01.2025)
Published in Psychophysiology (01.01.2025)
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Reductions in synaptic marker SV2A in early-course Schizophrenia
Yoon, Jong H., Zhang, Zhener, Mormino, Elizabeth, Davidzon, Guido, Minzenberg, Michael J., Ballon, Jacob, Kalinowski, Agnieszka, Hardy, Kate, Naganawa, Mika, Carson, Richard E., Khalighi, Mehdi, Park, Jun Hyung, Levinson, Douglas F., Chin, Frederick T.
Published in Journal of psychiatric research (01.05.2023)
Published in Journal of psychiatric research (01.05.2023)
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Brivaracetam, a selective high‐affinity synaptic vesicle protein 2A (SV2A) ligand with preclinical evidence of high brain permeability and fast onset of action
Nicolas, Jean‐Marie, Hannestad, Jonas, Holden, Daniel, Kervyn, Sophie, Nabulsi, Nabeel, Tytgat, Dominique, Huang, Yiyun, Chanteux, Hugues, Staelens, Ludovicus, Matagne, Alain, Mathy, François‐Xavier, Mercier, Joël, Stockis, Armel, Carson, Richard E., Klitgaard, Henrik
Published in Epilepsia (Copenhagen) (01.02.2016)
Published in Epilepsia (Copenhagen) (01.02.2016)
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Imaging the fetal nonhuman primate brain with SV2A positron emission tomography (PET)
Rossano, Samantha, Toyonaga, Takuya, Berg, Eric, Lorence, Isabella, Fowles, Krista, Nabulsi, Nabeel, Ropchan, Jim, Li, Songye, Ye, Yunpeng, Felchner, Zachary, Kukis, David, Huang, Yiyun, Benveniste, Helene, Tarantal, Alice F., Groman, Stephanie, Carson, Richard E.
Published in European journal of nuclear medicine and molecular imaging (01.09.2022)
Published in European journal of nuclear medicine and molecular imaging (01.09.2022)
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Increased Inflammation and Unchanged Density of Synaptic Vesicle Glycoprotein 2A (SV2A) in the Postmortem Frontal Cortex of Alzheimer’s Disease Patients
Metaxas, Athanasios, Thygesen, Camilla, Briting, Sanne R. R., Landau, Anne M., Darvesh, Sultan, Finsen, Bente
Published in Frontiers in cellular neuroscience (05.12.2019)
Published in Frontiers in cellular neuroscience (05.12.2019)
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A multicenter Phase II randomized, placebo-controlled single-blind trial with the SV2A ligand seletracetam in photosensitive epilepsy patients
Kasteleijn-Nolst Trenité, Dorothee, Stockis, Armel, Hirsch, Edouard, Genton, Pierre, Abou-Khalil, Bassel W., French, Jacqueline A., Masnou, Pascal, Löscher, Wolfgang
Published in Epilepsy & behavior (01.03.2025)
Published in Epilepsy & behavior (01.03.2025)
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Mapping changes in synaptic vesicle protein 2A (SV2A) in neurodegenerative diseases
Bavarsad, Mahsa Shanaki, Spina, Salvatore, Seeley, William W., Rabinovici, Gil D., Grinberg, Lea T.
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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SDI-118, a novel procognitive SV2A modulator: First-in-human randomized controlled trial including PET/fMRI assessment of target engagement
Botermans, Wouter, Koole, Michel, Van Laere, Koen, Savidge, Jonathan R., Kemp, John A., Sunaert, Stefan, Duffy, Maeve M., Ramael, Steven, Cesura, Andrea M., D’Ostilio, Kevin, Gossen, Denis, Madsen, Torsten M., Lodeweyckx, Thomas, de Hoon, Jan
Published in Frontiers in pharmacology (17.01.2023)
Published in Frontiers in pharmacology (17.01.2023)
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Evaluation of [18F]MNI-1126, an18F-labeled SV2A PET tracer in healthy, Parkinson disease and Alzheimer's disease subjects
Constantinescu, Cristian, Carroll, Vincent, Gouasmat, Alexandra, Tresse, Cedric, Russell, David, Gunn, Roger, Barret, Olivier, Rabiner, Eugenii, Marek, Kenneth
Published in The Journal of nuclear medicine (1978) (01.05.2019)
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Published in The Journal of nuclear medicine (1978) (01.05.2019)
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Drug characteristics derived from kinetic modeling: combined 11C-UCB-J human PET imaging with levetiracetam and brivaracetam occupancy of SV2A
Naganawa, Mika, Gallezot, Jean-Dominique, Finnema, Sjoerd J., Maguire, Ralph Paul, Mercier, Joël, Nabulsi, Nabeel B., Kervyn, Sophie, Henry, Shannan, Nicolas, Jean-Marie, Huang, Yiyun, Chen, Ming-Kai, Hannestad, Jonas, Klitgaard, Henrik, Stockis, Armel, Carson, Richard E.
Published in EJNMMI research (08.11.2022)
Published in EJNMMI research (08.11.2022)
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O11.3. SYNAPTIC MARKER PROTEIN SV2A IS REDUCED IN SCHIZOPHRENIA IN VIVO AND UNAFFECTED BY ANTIPSYCHOTICS IN RATS
Chika Onwordi, Ellis, Halff, Els, Whitehurst, Thomas, Mansur, Ayla, Cotel, Marie-Caroline, Wells, Lisa, Creeney, Hannah, Bonsall, David, Rogdaki, Maria, Shatalina, Ekaterina, Reis Marques, Tiago, Rabiner, Eugenii, Gunn, Roger, Natesan, Sridhar, Vernon, Anthony, Howes, Oliver D
Published in Schizophrenia bulletin (18.05.2020)
Published in Schizophrenia bulletin (18.05.2020)
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Age and sex effects on synaptic density in healthy humans as assessed with SV2A PET
Carson, Richard, Naganawa, Mika, Matuskey, David, Mecca, Adam, Pittman, Brian, Toyonaga, Takuya, Lu, Yihuan, Dias, Mark, Nabulsi, Nabeel, Finnema, Sjoerd, Chen, Ming-Kai, Malison, Robert, Esterlis, Irina, Dyck, Christopher Van, Huang, Yiyun
Published in The Journal of nuclear medicine (1978) (01.05.2018)
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Published in The Journal of nuclear medicine (1978) (01.05.2018)
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Evaluation of brivaracetam, a novel SV2A ligand, in the photosensitivity model
Kasteleijn-Nolst Trenité, D G A, Genton, P, Parain, D, Masnou, P, Steinhoff, B J, Jacobs, T, Pigeolet, E, Stockis, A, Hirsch, E
Published in Neurology (04.09.2007)
Published in Neurology (04.09.2007)
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Drug characteristics derived from kinetic modeling: combined 11 C-UCB-J human PET imaging with levetiracetam and brivaracetam occupancy of SV2A
Naganawa, Mika, Gallezot, Jean-Dominique, Finnema, Sjoerd J, Maguire, Ralph Paul, Mercier, Joël, Nabulsi, Nabeel B, Kervyn, Sophie, Henry, Shannan, Nicolas, Jean-Marie, Huang, Yiyun, Chen, Ming-Kai, Hannestad, Jonas, Klitgaard, Henrik, Stockis, Armel, Carson, Richard E
Published in EJNMMI research (08.11.2022)
Published in EJNMMI research (08.11.2022)
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Tracer kinetic analysis of the SV2A ligand ^sup 11^C-UCBA as a PET marker for synaptic density in humans
Lubberink, Mark, Appel, Lieuwe, Daging, Johannes, Lindskog, Karolina, Danfors, Torsten, Larsson, Elna-Marie, Kumlien, Eva, Antoni, Gunnar
Published in The Journal of nuclear medicine (1978) (01.05.2017)
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Published in The Journal of nuclear medicine (1978) (01.05.2017)
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Tracer kinetic analysis of the SV2A ligand 11 C-UCBA as a PET marker for synaptic density in humans
Lubberink, Mark, Appel, Lieuwe, Gaging, Johannes, Lindskog, Karolina, Danfors, Torsten, Larsson, Elna-Marie, Kumlien, Eva, Antoni, Gunnar
Published in The Journal of nuclear medicine (1978) (2017)
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Published in The Journal of nuclear medicine (1978) (2017)
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