SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML
Kung Sutherland, May S., Walter, Roland B., Jeffrey, Scott C., Burke, Patrick J., Yu, Changpu, Kostner, Heather, Stone, Ivan, Ryan, Maureen C., Sussman, Django, Lyon, Robert P., Zeng, Weiping, Harrington, Kimberly H., Klussman, Kerry, Westendorf, Lori, Meyer, David, Bernstein, Irwin D., Senter, Peter D., Benjamin, Dennis R., Drachman, Jonathan G., McEarchern, Julie A.
Published in Blood (22.08.2013)
Published in Blood (22.08.2013)
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Journal Article
Antibody-Dependent Cell-Mediated Cytotoxicity Overcomes NK Cell Resistance in MLL-Rearranged Leukemia Expressing Inhibitory KIR Ligands but Not Activating Ligands
WING KEUNG CHAN, MAY KUNG SUTHERLAND, YING LI, ZALEVSKY, Jonathan, SCHELL, Sarah, LEUNG, Wing
Published in Clinical cancer research (15.11.2012)
Published in Clinical cancer research (15.11.2012)
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Journal Article
Lysosomal Trafficking and Cysteine Protease Metabolism Confer Target-specific Cytotoxicity by Peptide-linked Anti-CD30-Auristatin Conjugates
Sutherland, May S. Kung, Sanderson, Russell J., Gordon, Kristine A., Andreyka, Jamie, Cerveny, Charles G., Yu, Changpu, Lewis, Timothy S., Meyer, Damon L., Zabinski, Roger F., Doronina, Svetlana O., Senter, Peter D., Law, Che-Leung, Wahl, Alan F.
Published in The Journal of biological chemistry (14.04.2006)
Published in The Journal of biological chemistry (14.04.2006)
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Journal Article
Sclerostin Inhibition of Wnt-3a-induced C3H10T1/2 Cell Differentiation Is Indirect and Mediated by Bone Morphogenetic Proteins
Winkler, David G., Sutherland, May S. Kung, Ojala, Ethan, Turcott, Eileen, Geoghegan, James C., Shpektor, Diana, Skonier, John E., Yu, Changpu, Latham, John A.
Published in The Journal of biological chemistry (28.01.2005)
Published in The Journal of biological chemistry (28.01.2005)
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Journal Article
Osteocyte control of bone formation via sclerostin, a novel BMP antagonist
Latham, John A, Winkler, David G, Sutherland, May Kung, Geoghegan, James C, Yu, Changpu, Hayes, Trenton, Skonier, John E, Shpektor, Diana, Jonas, Mechtild, Kovacevich, Brian R, Staehling-Hampton, Karen, Appleby, Mark, Brunkow, Mary E
Published in The EMBO journal (01.12.2003)
Published in The EMBO journal (01.12.2003)
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Journal Article
Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation
Sutherland, May Kung, Geoghegan, James C., Yu, Changpu, Turcott, Eileen, Skonier, John E., Winkler, David G., Latham, John A.
Published in Bone (New York, N.Y.) (01.10.2004)
Published in Bone (New York, N.Y.) (01.10.2004)
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Journal Article
Potent antitumor activity of the anti-CD19 auristatin antibody drug conjugate hBU12-vcMMAE against rituximab-sensitive and -resistant lymphomas
Gerber, Hans-Peter, Kung-Sutherland, May, Stone, Ivan, Morris-Tilden, Carol, Miyamoto, Jamie, McCormick, Renee, Alley, Stephen C., Okeley, Nicole, Hayes, Brad, Hernandez-Ilizaliturri, Francisco J., McDonagh, Charlotte F., Carter, Paul J., Benjamin, Dennis, Grewal, Iqbal S.
Published in Blood (30.04.2009)
Published in Blood (30.04.2009)
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Journal Article
Characterization of SGN-CD123A, A Potent CD123-Directed Antibody-Drug Conjugate for Acute Myeloid Leukemia
Li, Fu, Sutherland, May Kung, Yu, Changpu, Walter, Roland B, Westendorf, Lori, Valliere-Douglass, John, Pan, Lucy, Cronkite, Ashley, Sussman, Django, Klussman, Kerry, Ulrich, Michelle, Anderson, Martha E, Stone, Ivan J, Zeng, Weiping, Jonas, Mechthild, Lewis, Timothy S, Goswami, Maitrayee, Wang, Sa A, Senter, Peter D, Law, Che-Leung, Feldman, Eric J, Benjamin, Dennis R
Published in Molecular cancer therapeutics (01.02.2018)
Published in Molecular cancer therapeutics (01.02.2018)
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Journal Article
Anti-leukemic activity of Lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia
Sutherland, May Kung, Yu, Changpu, Lewis, Timothy S., Miyamoto, Jamie B., Morris-Tilden, Carol A., Jonas, Mechthild, Sutherland, Jennifer, Nesterova, Albina, Gerber, Hans-Peter, Sievers, Eric L., Grewal, Iqbal S., Law, Che-Leung
Published in mAbs (01.09.2009)
Published in mAbs (01.09.2009)
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Journal Article
5-Azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia
Sutherland, May Kung, Yu, Changpu, Anderson, Martha, Zeng, Weiping, van Rooijen, Nico, Sievers, Eric L., Grewal, Iqbal S., Law, Che-Leung
Published in mAbs (01.07.2010)
Published in mAbs (01.07.2010)
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Journal Article
The Biological Activities of 1α,25-Dihydroxyvitamin D3 and Its Synthetic Analog 1α,25-Dihydroxy-16-ene-vitamin D3 in Normal Human Osteoblastic Cells and Human Osteosarcoma SaOS-2 Cells Are Modulated by 17-β Estradiol and Dependent on Stage of Differentiation
RAO, Leticia G., LIU, Lily J.-F., RAWLINS, Myrna R., MCBROOM, Robert J., MURRAY, Timothy M., REDDY, G. Satyanarayama, USKOKOVIC, Milan R., RAO, D. Sunita, SUTHERLAND, May Kung
Published in Biological and Pharmaceutical Bulletin (2001)
Published in Biological and Pharmaceutical Bulletin (2001)
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Journal Article
33 CD33 ANTIBODIES AND USE OF SAME TO TREAT CANCER
JEFFREY SCOTT, SUSSMAN DJANGO, RYAN MAUREEN, BURKE PATRICK, SUTHERLAND MAY KUNG
Year of Publication 14.04.2020
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Year of Publication 14.04.2020
Patent
SP500263, a novel SERM, blocks osteoclastogenesis in a human bone cell model: role of IL-6 and GM-CSF
Sutherland, May S.Kung, Lipps, Stephanie G, Patnaik, Nandita, Gayo-Fung, Leah M, Khammungkune, Sak, Xie, Weilin, Brady, Helen A, Barbosa, Miguel S, Anderson, David W, Stein, Bernd
Published in Cytokine (Philadelphia, Pa.) (01.07.2003)
Published in Cytokine (Philadelphia, Pa.) (01.07.2003)
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Journal Article
A sugar engineered non-fucosylated anti-CD40 antibody, SEA-CD40, with enhanced immune stimulatory activity alone and in combination with immune checkpoint inhibitors
Gardai, Shyra Jane, Epp, Angela, Linares, Germein, Westendorf, Loir, Sutherland, May Kung, Neff-LaFord, Haley, Drachman, Jonathan Gregor, Peng, Stanford, Law, Che-Leung
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article
The biological activities of 1alpha,25-dihydroxyvitamin D3 and its synthetic analog 1alpha,25-dihydroxy-16-ene-vitamin D3 in normal human osteoblastic cells and human osteosarcoma SaOS-2 cells are modulated by 17-beta estradiol and dependent on stage of differentiation
Rao, L G, Liu, L J, Rawlins, M R, McBroom, R J, Murray, T M, Reddy, G S, Uskokovic, M R, Rao, D S, Sutherland, M K
Published in Biological & pharmaceutical bulletin (2001)
Published in Biological & pharmaceutical bulletin (2001)
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Journal Article