Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors
Davies, Christopher W., Oh, Angela J., Mroue, Rana, Steffek, Micah, Bruning, John M., Xiao, Yang, Feng, Siyu, Jayakar, Sangeeta, Chan, Emily, Arumugam, Vidhyalakshmi, Uribe, Sean Carlo, Drummond, Jake, Frommlet, Alexandra, Lu, Cheng, Franke, Yvonne, Merchant, Mark, Koeppen, Hartmut, Quinn, John G., Malhotra, Sushant, Do, Steve, Gazzard, Lewis, Purkey, Hans E., Rudolph, Joachim, Mulvihill, Melinda M., Koerber, James T., Wang, Weiru, Evangelista, Marie
Published in Nature biotechnology (01.05.2022)
Published in Nature biotechnology (01.05.2022)
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Journal Article
Synthesis and Reactivity of Unique Heterocyclic Structures en Route to Substituted Diamines
Olson, David E, Maruniak, Autumn, Malhotra, Sushant, Trost, Barry M, Du Bois, J
Published in Organic letters (01.07.2011)
Published in Organic letters (01.07.2011)
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Journal Article
Chemoselective sp2-sp3 cross-couplings: iron-catalyzed alkyl transfer to dihaloaromatics
Malhotra, Sushant, Seng, Pamela S, Koenig, Stefan G, Deese, Alan J, Ford, Kevin A
Published in Organic letters (19.07.2013)
Published in Organic letters (19.07.2013)
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Journal Article
Development of the Regiodivergent Asymmetric Prenylation of 3‐Substituted Oxindoles
Trost, Barry M., Chan, Walter H., Malhotra, Sushant
Published in Chemistry : a European journal (28.03.2017)
Published in Chemistry : a European journal (28.03.2017)
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Journal Article
Fit-for-Purpose Synthesis of a KRASG12C Covalent Inhibitor, via a Diastereoselective Hayashi Arylation
Molinaro, Carmela, Wong, Nicholas, White, Nicholas A., Sirois, Lauren E., Bigler, Raphael, Bindschaedler, Quentin P., Do, Steven, Malhotra, Sushant, Gosselin, Francis
Published in Organic process research & development (16.08.2024)
Published in Organic process research & development (16.08.2024)
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Journal Article
Fit-for-Purpose Synthesis of a KRAS G12C Covalent Inhibitor, via a Diastereoselective Hayashi Arylation
Molinaro, Carmela, Wong, Nicholas, White, Nicholas A., Sirois, Lauren E., Bigler, Raphael, Bindschaedler, Quentin P., Do, Steven, Malhotra, Sushant, Gosselin, Francis
Published in Organic process research & development (16.08.2024)
Published in Organic process research & development (16.08.2024)
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Journal Article
Chemoselective sp(2)-sp(3) Cross-Couplings: Iron-Catalyzed Alkyl Transfer to Dihaloaromatics
Malhotra, Sushant, Seng, Pamela S., Koenig, Stefan G., Deese, Alan J., Ford, Kevin A.
Published in Organic letters (19.07.2013)
Published in Organic letters (19.07.2013)
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Journal Article
Chemoselective Chromium(II)-Catalyzed Cross-Coupling Reactions of Dichlorinated Heteroaromatics with Functionalized Aryl Grignard Reagents
Steib, Andreas K., Kuzmina, Olesya M., Fernandez, Sarah, Malhotra, Sushant, Knochel, Paul
Published in Chemistry : a European journal (26.01.2015)
Published in Chemistry : a European journal (26.01.2015)
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Journal Article
AzidoTMT Enables Direct Enrichment and Highly Multiplexed Quantitation of Proteome-Wide Functional Residues
Ma, Taylur P., Izrael-Tomasevic, Anita, Mroue, Rana, Budayeva, Hanna, Malhotra, Sushant, Raisner, Ryan, Evangelista, Marie, Rose, Christopher M., Kirkpatrick, Donald S., Yu, Kebing
Published in Journal of proteome research (07.07.2023)
Published in Journal of proteome research (07.07.2023)
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Journal Article
Process Development Overcomes a Challenging Pd-Catalyzed C–N Coupling for the Synthesis of RORc Inhibitor GDC-0022
Sirois, Lauren E, Lao, David, Xu, Jie, Angelaud, Rémy, Tso, Jerry, Scott, Brandon, Chakravarty, Paroma, Malhotra, Sushant, Gosselin, Francis
Published in Organic process research & development (17.04.2020)
Published in Organic process research & development (17.04.2020)
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Journal Article
Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors
Nilewski, Christian, Labadie, Sharada, Wei, Binqing, Malhotra, Sushant, Do, Steven, Gazzard, Lewis, Liu, Li, Shao, Cheng, Murray, Jeremy, Izrayelit, Yevgeniy, Gustafson, Amy, Endres, Nicholas F., Ma, Fang, Ye, Xin, Zou, Jun, Evangelista, Marie
Published in ACS medicinal chemistry letters (11.01.2024)
Published in ACS medicinal chemistry letters (11.01.2024)
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Journal Article