Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel–Lindau (VHL) E3 Ubiquitin Ligase
Zhao, Quanju, Ren, Chaowei, Liu, Linyi, Chen, Jinju, Shao, Yubao, Sun, Ning, Sun, Renhong, Kong, Ying, Ding, Xinyu, Zhang, Xianfang, Xu, Youwei, Yang, Bei, Yin, Qianqian, Yang, Xiaobao, Jiang, Biao
Published in Journal of medicinal chemistry (24.10.2019)
Published in Journal of medicinal chemistry (24.10.2019)
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Journal Article
DeepPROTACs is a deep learning-based targeted degradation predictor for PROTACs
Li, Fenglei, Hu, Qiaoyu, Zhang, Xianglei, Sun, Renhong, Liu, Zhuanghua, Wu, Sanan, Tian, Siyuan, Ma, Xinyue, Dai, Zhizhuo, Yang, Xiaobao, Gao, Shenghua, Bai, Fang
Published in Nature communications (21.11.2022)
Published in Nature communications (21.11.2022)
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Journal Article
Construction of an IMiD-based azide library as a kit for PROTAC research
Liu, Haixia, Sun, Renhong, Ren, Chaowei, Qiu, Xing, Yang, Xiaobao, Jiang, Biao
Published in Organic & biomolecular chemistry (06.01.2021)
Published in Organic & biomolecular chemistry (06.01.2021)
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Journal Article
Development of the nonreceptor tyrosine kinase FER-targeting PROTACs as a potential strategy for antagonizing ovarian cancer cell motility and invasiveness
Zhang, Yanchun, Xiong, Xuexue, Sun, Renhong, Zhu, Xiaotong, Wang, Chen, Jiang, Biao, Yang, Xiaobao, Li, Dake, Fan, Gaofeng
Published in The Journal of biological chemistry (01.06.2023)
Published in The Journal of biological chemistry (01.06.2023)
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Journal Article
Design, synthesis and biological evaluation of novel quinazolinone derivatives as CRBN E3 ligase modulators
Liu, Linyi, Sun, Renhong, Liu, Haixia, Ren, Chaowei, Zhou, Yuedong, Qiu, Xing, Kong, Ying, Jiang, Biao, Yang, Xiaobao
Published in European journal of medicinal chemistry (05.02.2023)
Published in European journal of medicinal chemistry (05.02.2023)
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Journal Article
Nickel-Catalyzed [2+2+2] Cycloaddition of Alkyne-Nitriles with Alkynes Assisted by Lewis Acids: Efficient Synthesis of Fused Pyridines
You, Xu, Xie, Xin, Wang, Gaonan, Xiong, Meijun, Sun, Renhong, Chen, Haoyi, Liu, Yuanhong
Published in Chemistry : a European journal (14.11.2016)
Published in Chemistry : a European journal (14.11.2016)
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Journal Article
Discovery of a Brigatinib Degrader SIAIS164018 with Destroying Metastasis-Related Oncoproteins and a Reshuffling Kinome Profile
Ren, Chaowei, Sun, Ning, Liu, Haixia, Kong, Ying, Sun, Renhong, Qiu, Xing, Chen, Jinju, Li, Yan, Zhang, Jianshui, Zhou, Yuedong, Zhong, Hui, Yin, Qianqian, Song, Xiaoling, Yang, Xiaobao, Jiang, Biao
Published in Journal of medicinal chemistry (08.07.2021)
Published in Journal of medicinal chemistry (08.07.2021)
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Journal Article
Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia
Luo, Ziwei, Lin, Chencen, Yu, Chuwei, Yuan, Changxian, Wu, Wenyong, Xu, Xiaowei, Sun, Renhong, Jia, Yan, Wang, Yafang, Shen, Jie, Wang, Dingyan, Wang, Sinan, Jiang, Hualiang, Jiang, Biao, Yang, Xiaobao, Xie, Chengying
Published in Cancer research (Chicago, Ill.) (22.10.2024)
Published in Cancer research (Chicago, Ill.) (22.10.2024)
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NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers
Zhu, Xiaotong, Li, Ye, Liu, Haixia, Wang, Yuetong, Sun, Renhong, Jiang, Zhenzhou, Hou, Chun, Hou, Xianyu, Huang, Suming, Zhang, Huijuan, Wang, Haopeng, Jiang, Biao, Yang, Xiaobao, Xu, Bin, Fan, Gaofeng
Published in Cell chemical biology (20.06.2024)
Published in Cell chemical biology (20.06.2024)
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The PROTAC selectively degrading Bcl-xL represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth
Zhang, Shaoqing, Chen, Yue, Xu, Zhongli, Yang, Jun, Sun, Renhong, Wang, Juan, Sun, Yiming, Jiang, Biao, Yang, Xiaobao, Tan, Wenfu
Published in Theranostics (01.01.2022)
Published in Theranostics (01.01.2022)
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Journal Article
Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement
Gray, Zach H., Chakraborty, Damayanti, Duttweiler, Reuben R., Alekbaeva, Gulnaz D., Murphy, Sedona E., Chetal, Kashish, Ji, Fei, Ferman, Benjamin I., Honer, Madison A., Wang, Zhentian, Myers, Cynthia, Sun, Renhong, Kaniskan, H. Ümit, Toma, Monika Maria, Bondarenko, Elena A., Santoro, John N., Miranda, Christopher, Dillingham, Megan E., Tang, Ran, Gozani, Or, Jin, Jian, Skorski, Tomasz, Duy, Cihangir, Lee, Hayan, Sadreyev, Ruslan I., Whetstine, Johnathan R.
Published in Cell (12.10.2023)
Published in Cell (12.10.2023)
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Zirconium-Mediated Multicomponent Reactions of 1,3-Butadiynes with Ylidenemalononitriles to Form Functionalized 1,8-Naphthyridine and Cyclopenta[b]pyridine Derivatives
Yu, Shasha, Sun, Renhong, Chen, Haoyi, Xie, Xin, Liu, Yuanhong
Published in Chemistry : a European journal (19.01.2015)
Published in Chemistry : a European journal (19.01.2015)
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Journal Article
Cp2TiCl2-catalyzed cis-hydroalumination of propargylic amines with Red-Al: stereoselective synthesis of Z-configured allylic amines
Sun, Renhong, Liu, Jun, Yang, Shuang, Chen, Ming, Sun, Ning, Chen, Haoyi, Xie, Xin, You, Xu, Li, Shi, Liu, Yuanhong
Published in Chemical communications (Cambridge, England) (14.04.2015)
Published in Chemical communications (Cambridge, England) (14.04.2015)
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Journal Article
The PROTAC selectively degrading Bcl-x L represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth
Zhang, Shaoqing, Chen, Yue, Xu, Zhongli, Yang, Jun, Sun, Renhong, Wang, Juan, Sun, Yiming, Jiang, Biao, Yang, Xiaobao, Tan, Wenfu
Published in Theranostics (2022)
Published in Theranostics (2022)
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SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF
LIU LINYI, YANG XIAOBAO, JIANG BIAO, SUN NING, SUN RENHONG, REN CHAOWEI, QIU XING
Year of Publication 21.02.2024
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Year of Publication 21.02.2024
Patent
Aryne [3+2] cycloaddition with N-sulfonylpyridinium imides and in situ generated N-sulfonylisoquinolinium imides: a potential route to pyrido[1,2-b]indazoles and indazolo[3,2-a]isoquinolines
Zhao, Jingjing, Li, Pan, Wu, Chunrui, Chen, Hongli, Ai, Wenying, Sun, Renhong, Ren, Hailong, Larock, Richard C., Shi, Feng
Published in Organic & biomolecular chemistry (07.03.2012)
Published in Organic & biomolecular chemistry (07.03.2012)
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글루타르이미드 골격을 기초로 하는 화합물 및 그 응용
YANG XIAOBAO, JIANG BIAO, SUN NING, SUN RENHONG, REN CHAOWEI, QIU XING
Year of Publication 28.10.2022
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Year of Publication 28.10.2022
Patent
Cp2TiCl2-catalyzed cis-hydroalumination of propargylic amines with Red-Al: stereoselective synthesis of Z-configured allylic aminesElectronic supplementary information (ESI) available: Experimental details, NMR spectra of all compounds, and X-ray crystallography of 7a and 11. CCDC 1040902 (7a) and 1040903 (11). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5cc00950b
Sun, Renhong, Liu, Jun, Yang, Shuang, Chen, Ming, Sun, Ning, Chen, Haoyi, Xie, Xin, You, Xu, Li, Shi, Liu, Yuanhong
Year of Publication 26.03.2015
Year of Publication 26.03.2015
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