Search Results - "SUN, ERIC, T" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of the Macrocycle 11-(2-Pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (SB1518), a Potent Janus Kinase 2/Fms-Like Tyrosine Kinase-3 (JAK2/FLT3) Inhibitor for the Treatment of Myelofibrosis and Lymphoma

Discovery of the Macrocycle 11-(2-Pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (SB1518), a Potent Janus Kinase 2/Fms-Like Tyrosine Kinase-3 (JAK2/FLT3) Inhibitor for the Treatment of Myelofibrosis and Lymphoma

by William, Anthony D, Lee, Angeline C.-H, Blanchard, Stéphanie, Poulsen, Anders, Teo, Ee Ling, Nagaraj, Harish, Tan, Evelyn, Chen, Dizhong, Williams, Meredith, Sun, Eric T, Goh, Kee Chuan, Ong, Wai Chung, Goh, Siok Kun, Hart, Stefan, Jayaraman, Ramesh, Pasha, Mohammed Khalid, Ethirajulu, Kantharaj, Wood, Jeanette M, Dymock, Brian W
Published in Journal of medicinal chemistry (14.07.2011)

Get full text

Journal Article

Discovery of Kinase Spectrum Selective Macrocycle (16E)-14-Methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a Potent Inhibitor of Cyclin Dependent Kinases (CDKs), Janus Kinase 2 (JAK2), and Fms-like Tyrosine Kinase-3 (FLT3) for the Treatment of Cancer

Discovery of Kinase Spectrum Selective Macrocycle (16E)-14-Methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a Potent Inhibitor of Cyclin Dependent Kinases (CDKs), Janus Kinase 2 (JAK2), and Fms-like Tyrosine Kinase-3 (FLT3) for the Treatment of Cancer

by William, Anthony D, Lee, Angeline C.-H, Goh, Kee Chuan, Blanchard, Stéphanie, Poulsen, Anders, Teo, Ee Ling, Nagaraj, Harish, Lee, Chai Ping, Wang, Haishan, Williams, Meredith, Sun, Eric T, Hu, Changyong, Jayaraman, Ramesh, Pasha, Mohammed Khalid, Ethirajulu, Kantharaj, Wood, Jeanette M, Dymock, Brian W
Published in Journal of medicinal chemistry (12.01.2012)

Get full text

Journal Article

Discovery of (2E)-3-{2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide (SB939), an Orally Active Histone Deacetylase Inhibitor with a Superior Preclinical Profile

by Wang, Haishan, Yu, Niefang, Chen, Dizhong, Lee, Ken Chi Lik, Lye, Pek Ling, Chang, Joyce Wei Wei, Deng, Weiping, Ng, Melvin Chi Yeh, Lu, Ting, Khoo, Mui Ling, Poulsen, Anders, Sangthongpitag, Kanda, Wu, Xiaofeng, Hu, Changyong, Goh, Kee Chuan, Wang, Xukun, Fang, Lijuan, Goh, Kay Lin, Khng, Hwee Hoon, Goh, Siok Kun, Yeo, Pauline, Liu, Xin, Bonday, Zahid, Wood, Jeanette M, Dymock, Brian W, Kantharaj, Ethirajulu, Sun, Eric T
Published in Journal of medicinal chemistry (14.07.2011)

Get full text

Journal Article

Discovery of the Macrocycle (9E)-15-(2-(Pyrrolidin-1-yl)ethoxy)-7,12,25-trioxa-19,21,24-triaza-tetracyclo[18.3.1.1(2,5).1(14,18)]hexacosa-1(24),2,4,9,14(26),15,17,20,22-nonaene (SB1578), a Potent Inhibitor of Janus Kinase 2/Fms-LikeTyrosine Kinase-3 (JAK2/FLT3) for the Treatment of Rheumatoid Arthritis

Discovery of the Macrocycle (9E)-15-(2-(Pyrrolidin-1-yl)ethoxy)-7,12,25-trioxa-19,21,24-triaza-tetracyclo[18.3.1.1(2,5).1(14,18)]hexacosa-1(24),2,4,9,14(26),15,17,20,22-nonaene (SB1578), a Potent Inhibitor of Janus Kinase 2/Fms-LikeTyrosine Kinase-3 (JAK2/FLT3) for the Treatment of Rheumatoid Arthritis

by William, Anthony D, Lee, Angeline C.-H, Poulsen, Anders, Goh, Kee Chuan, Madan, Babita, Hart, Stefan, Tan, Evelyn, Wang, Haishan, Nagaraj, Harish, Chen, Dizhong, Lee, Chai Ping, Sun, Eric T, Jayaraman, Ramesh, Pasha, Mohammad Khalid, Ethirajulu, Kantharaj, Wood, Jeanette M, Dymock, Brian W
Published in Journal of medicinal chemistry (22.03.2012)

Get full text

Journal Article

Acylurea connected straight chain hydroxamates as novel histone deacetylase inhibitors: Synthesis, SAR, and in vivo antitumor activity

Acylurea connected straight chain hydroxamates as novel histone deacetylase inhibitors: Synthesis, SAR, and in vivo antitumor activity

by Wang, Haishan, Lim, Ze-Yi, Zhou, Yan, Ng, Melvin, Lu, Ting, Lee, Ken, Sangthongpitag, Kanda, Goh, Kee Chuan, Wang, Xukun, Wu, Xiaofeng, Khng, Hwee Hoon, Goh, Siok Kun, Ong, Wai Chung, Bonday, Zahid, Sun, Eric T.
Published in Bioorganic & medicinal chemistry letters (01.06.2010)

Get full text

Journal Article

N-Hydroxy-1,2-disubstituted-1H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: design, synthesis, SAR studies, and in vivo antitumor activity

N-Hydroxy-1,2-disubstituted-1H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: design, synthesis, SAR studies, and in vivo antitumor activity

by Wang, Haishan, Yu, Niefang, Song, Hongyan, Chen, Dizhong, Zou, Yong, Deng, Weiping, Lye, Pek Ling, Chang, Joyce, Ng, Melvin, Sun, Eric T, Sangthongpitag, Kanda, Wang, Xukun, Wu, Xiaofeng, Khng, Hwee Hoon, Fang, Lijuan, Goh, Siok Kun, Ong, Wai Chung, Bonday, Zahid, Stünkel, Walter, Poulsen, Anders, Entzeroth, Michael
Published in Bioorganic & medicinal chemistry letters (01.03.2009)

Get full text

Journal Article

Discovery of a Novel, Orally Active, Small Molecule Gonadotropin-Releasing Hormone (GnRH) Receptor Antagonist

Discovery of a Novel, Orally Active, Small Molecule Gonadotropin-Releasing Hormone (GnRH) Receptor Antagonist

by Li, Haitao, Anderes, Kenna L, Kraynov, Eugenia A, Luthin, David R, Do, Quyen-Quyen, Hong, Yufeng, Tompkins, Eileen, Sun, Eric T, Rajapakse, Ranjan, Pathak, Ved P, Christie, Lance C, Vazir, Haresh, Castillo, Rosemary, Gregory, Margaret L, Castro, Mary, Nared-Hood, Karen, Paderes, Genevieve, Anderson, Mark B
Published in Journal of medicinal chemistry (01.06.2006)

Get full text

Journal Article

Discovery of a Novel, Orally Active, Small Molecule Gonadotropin-Releasing Hormone (GnRH) Receptor Antagonist

Discovery of a Novel, Orally Active, Small Molecule Gonadotropin-Releasing Hormone (GnRH) Receptor Antagonist

by Li, Haitao, Anderes, Kenna L, Kraynov, Eugenia A, Luthin, David R, Do, Quyen-Quyen, Hong, Yufeng, Tompkins, Eileen, Sun, Eric T, Rajapakse, Ranjan, Pathak, Ved P, Christie, Lance C, Feng, Jun, Vazir, Haresh, Castillo, Rosemary, Gregory, Margaret L, Castro, Mary, Nared-Hood, Karen, Paderes, Genevieve, Anderson, Mark B
Published in Journal of medicinal chemistry (21.09.2006)

Get full text

Journal Article

Synthesis of (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid derivatives. Analysis of diastereomeric purity

Synthesis of (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid derivatives. Analysis of diastereomeric purity

by Rich, Daniel H, Sun, Eric T, Boparai, Amrit S
Published in Journal of organic chemistry (01.09.1978)

Get full text

Journal Article

Synthesis of analogs of the carboxyl protease inhibitor pepstatin. Effect of structure on inhibition of pepsin and renin

Synthesis of analogs of the carboxyl protease inhibitor pepstatin. Effect of structure on inhibition of pepsin and renin

by Rich, Daniel H, Sun, Eric T. O, Ulm, Edgar
Published in Journal of medicinal chemistry (01.01.1980)

Get full text

Journal Article

An immunocytochemical study of the FMRFamide neuropeptide gene products in Drosophila

An immunocytochemical study of the FMRFamide neuropeptide gene products in Drosophila

by Schneider, L E, Sun, E T, Garland, D J, Taghert, P H
Published in Journal of comparative neurology (1911) (15.11.1993)

Get more information

Journal Article

OXYGEN LINKED PYRIMIDINE DER??ATIVES

OXYGEN LINKED PYRIMIDINE DER??ATIVES

by SUN ERIC T, POULSEN ANDERS, TAN YEE LING EVELYN, WILLIAM ANTHONY DEODAUNIA, BLANCHARD STEPHANIE, NAGARAJ HARISH KUMAR MYSORE, LEE CHENG HSIA ANGELINE
Year of Publication 26.03.2014

Get full text

Patent

HETEROALKYL LINKED PYRIMIDINE DERIVATIVES

HETEROALKYL LINKED PYRIMIDINE DERIVATIVES

by SUN ERIC T, POULSEN ANDERS, TAN YEE LING EVELYN, WILLIAM ANTHONY DEODAUNIA, BLANCHARD STEPHANIE, ETHIRAJULU KANTHARAJ, NAGARAJ HARISH KUMAR MYSORE, LEE CHENG HSIA ANGELINE, TEO EE LING
Year of Publication 07.10.2014

Get full text

Patent

HETEROALKYL LINKED PYRIMIDINE DERIVATIVES

HETEROALKYL LINKED PYRIMIDINE DERIVATIVES

by SUN ERIC T, POULSEN ANDERS, TAN YEE LING EVELYN, WILLIAM ANTHONY DEODAUNIA, BLANCHARD STEPHANIE, ETHIRAJULU KANTHARAJ, NAGARAJ HARISH KUMAR MYSORE, LEE CHENG HSIA ANGELINE, TEO EE LING
Year of Publication 26.03.2014

Get full text

Patent

1-Aminocyclobutane-1-carboxylate (ACBC): a specific antagonist of the N-methyl-D-aspartate receptor coupled glycine receptor

1-Aminocyclobutane-1-carboxylate (ACBC): a specific antagonist of the N-methyl-D-aspartate receptor coupled glycine receptor

by Hood, W F, Sun, E T, Compton, R P, Monahan, J B
Published in European journal of pharmacology (28.02.1989)

Get more information

Journal Article

N-Hydroxy-1,2-disubstituted-1 H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: Design, synthesis, SAR studies, and in vivo antitumor activity

N-Hydroxy-1,2-disubstituted-1 H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: Design, synthesis, SAR studies, and in vivo antitumor activity

by Wang, Haishan, Yu, Niefang, Song, Hongyan, Chen, Dizhong, Zou, Yong, Deng, Weiping, Lye, Pek Ling, Chang, Joyce, Ng, Melvin, Blanchard, Stéphanie, Sun, Eric T., Sangthongpitag, Kanda, Wang, Xukun, Goh, Kee Chuan, Wu, Xiaofeng, Khng, Hwee Hoon, Fang, Lijuan, Goh, Siok Kun, Ong, Wai Chung, Bonday, Zahid, Stünkel, Walter, Poulsen, Anders, Entzeroth, Michael
Published in Bioorganic & medicinal chemistry letters (2009)

Get full text

Journal Article

Discovery of the macrocycle (9E)-15-(2-(pyrrolidin-1-yl)ethoxy)-7,12,25-trioxa-19,21,24-triaza-tetracyclo[18.3.1.1(2,5).1(14,18)]hexacosa-1(24),2,4,9,14(26),15,17,20,22-nonaene (SB1578), a potent inhibitor of janus kinase 2/fms-like tyrosine kinase-3 (JAK2/FLT3) for the treatment of rheumatoid arthritis

Discovery of the macrocycle (9E)-15-(2-(pyrrolidin-1-yl)ethoxy)-7,12,25-trioxa-19,21,24-triaza-tetracyclo[18.3.1.1(2,5).1(14,18)]hexacosa-1(24),2,4,9,14(26),15,17,20,22-nonaene (SB1578), a potent inhibitor of janus kinase 2/fms-like tyrosine kinase-3 (JAK2/FLT3) for the treatment of rheumatoid arthritis

by William, Anthony D, Lee, Angeline C-H, Poulsen, Anders, Goh, Kee Chuan, Madan, Babita, Hart, Stefan, Tan, Evelyn, Wang, Haishan, Nagaraj, Harish, Chen, Dizhong, Lee, Chai Ping, Sun, Eric T, Jayaraman, Ramesh, Pasha, Mohammad Khalid, Ethirajulu, Kantharaj, Wood, Jeanette M, Dymock, Brian W
Published in Journal of medicinal chemistry (22.03.2012)

Get full text

Journal Article

Hydroxyethylaminosulfaminsyrederivater til anvendelse som inhibitorer af retrovirale proteaser

Hydroxyethylaminosulfaminsyrederivater til anvendelse som inhibitorer af retrovirale proteaser

by MUELLER, RICHARD, A, TALLEY, JOHN, J, SUN, ERIC, T, SUN, ERIC, T. 7614 PALMILLA DRIVE, GETMAN, DANIEL, VAZQUEZ, MICHAEL, L, GETMAN, DANIEL, P, DECRESCENZO, GARY, A
Year of Publication 02.11.1998

Get full text

Patent

OXYGEN LINKED PYRIMIDINE DERIVATIVES

OXYGEN LINKED PYRIMIDINE DERIVATIVES

by Sun, Eric T, Nagaraj, Harish Kumar Mysore, Poulsen, Anders, Blanchard, Stephanie, Tan, Yee Ling Evelyn, William, Anthony Deodaunia, Lee, Cheng Hsia Angeline
Year of Publication 04.08.2022

Get full text

Patent

Benzimidazole derivatives: preparation and pharmaceutical applications

Benzimidazole derivatives: preparation and pharmaceutical applications

by Sun, Eric T, Chen, DiZhong, Zou, Yong, Song, Hong Yan, Yu, Niefang
Year of Publication 11.08.2020

Get full text

Patent

1
2
3
4
5
6
7
8
9
10
11
Next
[15]