Loss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathway
Drosten, Matthias, Sum, Eleanor Y. M., Lechuga, Carmen G., Simón-Carrasco, Lucía, Jacob, Harrys K. C., García-Medina, Raquel, Huang, Sidong, Beijersbergen, Roderick L., Bernards, Rene, Barbacid, Mariano
Published in Proceedings of the National Academy of Sciences - PNAS (21.10.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (21.10.2014)
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Journal Article
Overexpression of LMO4 Induces Mammary Hyperplasia, Promotes Cell Invasion, and Is a Predictor of Poor Outcome in Breast Cancer
Eleanor Y. M. Sum, Segara, Davendra, Duscio, Belinda, Bath, Mary L., Field, Andrew S., Sutherland, Robert L., Lindeman, Geoffrey J., Visvader, Jane E., Cory, Suzanne
Published in Proceedings of the National Academy of Sciences - PNAS (24.05.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (24.05.2005)
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Journal Article
Defective Neural Tube Closure and Anteroposterior Patterning in Mice Lacking the LIM Protein LMO4 or Its Interacting Partner Deaf-1
Hahm, Kyungmin, Sum, Eleanor Y. M., Fujiwara, Yuko, Lindeman, Geoffrey J., Visvader, Jane E., Orkin, Stuart H.
Published in Molecular and Cellular Biology (01.03.2004)
Published in Molecular and Cellular Biology (01.03.2004)
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Journal Article
Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival
Drosten, Matthias, Dhawahir, Alma, Sum, Eleanor Y M, Urosevic, Jelena, Lechuga, Carmen G, Esteban, Luis M, Castellano, Esther, Guerra, Carmen, Santos, Eugenio, Barbacid, Mariano
Published in The EMBO journal (17.03.2010)
Published in The EMBO journal (17.03.2010)
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Journal Article
Loss of the LIM domain protein Lmo4 in the mammary gland during pregnancy impedes lobuloalveolar development
SUM, Eleanor Y. M, SHACKLETON, Mark, HAHM, Kyungmin, THOMAS, Richard M, O'REILLY, Lorraine A, WAGNER, Kay-Uwe, LINDEMAN, Geoffrey J, VISVADER, Jane E
Published in Oncogene (14.07.2005)
Published in Oncogene (14.07.2005)
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Journal Article
LMO4 expression in squamous cell carcinoma of the anterior tongue
Kwong, Rhonda A, Scarlett, Christopher J, Kalish, Larry H, Cole, Ian E, Kench, James G, Sum, Eleanor YM, Musgrove, Elizabeth A, Henshall, Susan M, Lindeman, Geoffrey J, Biankin, Andrew V, Visvader, Jane E, Sutherland, Robert L
Published in Histopathology (01.02.2011)
Published in Histopathology (01.02.2011)
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Journal Article
CPAP Is a Novel Stat5-Interacting Cofactor that Augments Stat5-Mediated Transcriptional Activity
Peng, Benjamin, Sutherland, Kate D, Sum, Eleanor Y. M, Olayioye, Monilola, Wittlin, Sergio, Tang, Tang K, Lindeman, Geoffrey J, Visvader, Jane E
Published in Molecular endocrinology (Baltimore, Md.) (01.09.2002)
Published in Molecular endocrinology (Baltimore, Md.) (01.09.2002)
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Journal Article
The LIM Domain Protein LMO4 Interacts with the Cofactor CtIP and the Tumor Suppressor BRCA1 and Inhibits BRCA1 Activity
Sum, Eleanor Y.M., Peng, Benjamin, Yu, Xin, Chen, Junjie, Byrne, Jennifer, Lindeman, Geoffrey J., Visvader, Jane E.
Published in The Journal of biological chemistry (08.03.2002)
Published in The Journal of biological chemistry (08.03.2002)
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Journal Article
The LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer
Visvader, J E, Venter, D, Hahm, K, Santamaria, M, Sum, E Y, O'Reilly, L, White, D, Williams, R, Armes, J, Lindeman, G J
Published in Proceedings of the National Academy of Sciences - PNAS (04.12.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (04.12.2001)
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Journal Article
Using cells devoid of RAS proteins as tools for drug discovery
Urosevic, Jelena, Sum, Eleanor Y.M., Moneo, Victoria, Drosten, Matthias, Dhawahir, Alma, Becerra, Mercedes, Carnero, Amancio, Barbacid, Mariano
Published in Molecular carcinogenesis (01.11.2009)
Published in Molecular carcinogenesis (01.11.2009)
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Journal Article
Dimerization of CtIP, a BRCA1- and CtBP-interacting Protein, Is Mediated by an N-terminal Coiled-coil Motif
Dubin, Manu J., Stokes, Philippa H., Sum, Eleanor Y.M., Williams, R. Scott, Valova, Valentina A., Robinson, Phillip J., Lindeman, Geoffrey J., Glover, J. N. Mark, Visvader, Jane E., Matthews, Jacqueline M.
Published in The Journal of biological chemistry (25.06.2004)
Published in The Journal of biological chemistry (25.06.2004)
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Journal Article
Mutational analysis of the LMO4 gene, encoding a BRCA1‐interacting protein, in breast carcinomas
Sutherland, Kate D., Visvader, Jane E., Choong, David Y.H., Sum, Eleanor Y.M., Lindeman, Geoffrey J., Campbell, Ian G.
Published in International journal of cancer (20.10.2003)
Published in International journal of cancer (20.10.2003)
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Journal Article
Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4
Matthews, Jacqueline M, Deane, Janet E, Mackay, Joel P, Kwan, Ann H.Y, Sum, Eleanor Y.M, Visvader, Jane E
Published in The EMBO journal (01.05.2003)
Published in The EMBO journal (01.05.2003)
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Journal Article
The LIM Domain Gene LM04 Inhibits Differentiation of Mammary Epithelial Cells in vitro and is Overexpressed in Breast Cancer
Visvader, Jane E., Venter, Deon, Hahm, Kyungmin, Santamaria, Margaret, Eleanor Y. M. Sum, O'Reilly, Lorraine, White, David, Williams, Rachael, Armes, Jane, Lindeman, Geoffrey J.
Published in Proceedings of the National Academy of Sciences - PNAS (04.12.2001)
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Published in Proceedings of the National Academy of Sciences - PNAS (04.12.2001)
Journal Article
A METHOD OF DIAGNOSIS AND TREATMENT AND AGENTS USEFUL FOR SAME
LINDEMAN, GEOFFREY JOHN, VISVADER, JANE ELLEN, SUM, ELEANOR Y. M, O'REILLY, LORRAINE ANN
Year of Publication 21.05.2013
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Year of Publication 21.05.2013
Patent
A METHOD OF DIAGNOSIS AND TREATMENT AND AGENTS USEFUL FOR SAME
VISVADER, JANE, ELLEN, LINDEMAN, GEOFFREY, JOHN, SUM, ELEANOR, Y., M, O'REILLY, LORRAINE, ANN
Year of Publication 21.03.2012
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Year of Publication 21.03.2012
Patent
A method of diagnosis and treatment of cancer involving LM04
SUM, ELEANOR Y M, LINDEMAN, GEOFFREY JOHN, VISVADER, JANE ELLEN, O'REILLY, LORRAINE ANN
Year of Publication 31.03.2011
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Year of Publication 31.03.2011
Patent
Method of diagnosis and treatment and agents useful for same
Visvader, Jane Ellen, Lindeman, Geoffrey John, Sum, Eleanor Y. M, O'Reilly, Lorraine Ann
Year of Publication 20.04.2010
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Year of Publication 20.04.2010
Patent