Discovery of Novel Agonists and Antagonists of the Free Fatty Acid Receptor 1 (FFAR1) Using Virtual Screening
Tikhonova, Irina G, Sum, Chi Shing, Neumann, Susanne, Engel, Stanislav, Raaka, Bruce M, Costanzi, Stefano, Gershengorn, Marvin C
Published in Journal of medicinal chemistry (14.02.2008)
Published in Journal of medicinal chemistry (14.02.2008)
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Journal Article
Identification of Residues Important for Agonist Recognition and Activation in GPR40
Sum, Chi Shing, Tikhonova, Irina G., Neumann, Susanne, Engel, Stanislav, Raaka, Bruce M., Costanzi, Stefano, Gershengorn, Marvin C.
Published in The Journal of biological chemistry (05.10.2007)
Published in The Journal of biological chemistry (05.10.2007)
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Journal Article
Bidirectional, Iterative Approach to the Structural Delineation of the Functional “Chemoprint” in GPR40 for Agonist Recognition
Tikhonova, Irina G, Sum, Chi Shing, Neumann, Susanne, Thomas, Craig J, Raaka, Bruce M, Costanzi, Stefano, Gershengorn, Marvin C
Published in Journal of medicinal chemistry (28.06.2007)
Published in Journal of medicinal chemistry (28.06.2007)
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Journal Article
An optimized agonist peptide of protease-activated receptor 4 and its use in a validated platelet-aggregation assay
Yang, Jing, Mapelli, Claudio, Wang, Zhaoqing, Sum, Chi Shing, Hua, Ji, Lawrence, R. Michael, Ni, Yan, Seiffert, Dietmar A.
Published in Platelets (Edinburgh) (03.10.2022)
Published in Platelets (Edinburgh) (03.10.2022)
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Journal Article
Establishing a High-content Analysis Method for Tubulin Polymerization to Evaluate Both the Stabilizing and Destabilizing Activities of Compounds
Sum, Chi Shing, Nickischer, Debra, Lei, Ming, Weston, Andrea, Zhang, Litao, Schweizer, Liang
Published in Current chemical genomics and translational medicine (07.02.2014)
Published in Current chemical genomics and translational medicine (07.02.2014)
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Journal Article
Cholesterol as a determinant of cooperativity in the M2 muscarinic cholinergic receptor
COLOZO, Alejandro T, PARK, Paul S.-H, CHI SHING SUM, PISTERZI, Luca F, WELLS, James W
Published in Biochemical pharmacology (15.07.2007)
Published in Biochemical pharmacology (15.07.2007)
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Journal Article
TNFR2에 대한 항체 및 이의 용도
TANG FANGQIANG, SUM CHI SHING, PEI YI, LEI MING, LIN BOR RUEI, HUANG HAICHUN, PRITSKER ALLA, LI HAN
Year of Publication 11.10.2023
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Year of Publication 11.10.2023
Patent
Potentiation of purinergic transmission by angiotensin in prostatic rat vas deferens
Sum, Chi‐Shing, Wan, David C.C., Cheung, Wing‐Tai
Published in British journal of pharmacology (01.07.1996)
Published in British journal of pharmacology (01.07.1996)
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Journal Article
Nature of the oligomers formed by muscarinic m2 acetylcholine receptors in Sf9 cells
Park, Paul, Sum, Chi Shing, Hampson, David R, Van Tol, Hubert H.M, Wells, James W
Published in European journal of pharmacology (01.06.2001)
Published in European journal of pharmacology (01.06.2001)
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Journal Article
Effects of N-Ethylmaleimide on Conformational Equilibria in Purified Cardiac Muscarinic Receptors
Sum, Chi Shing, Park, Paul S.-H., Wells, James W.
Published in The Journal of biological chemistry (27.09.2002)
Published in The Journal of biological chemistry (27.09.2002)
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Journal Article
Discovery of Two Novel Antiplatelet Clinical Candidates (BMS-986120 and BMS-986141) That Antagonize Protease-Activated Receptor 4
Priestley, E. Scott, Banville, Jacques, Deon, Daniel, Dubé, Laurence, Gagnon, Marc, Guy, Julia, Lapointe, Philippe, Lavallée, Jean-François, Martel, Alain, Plamondon, Serge, Rémillard, Roger, Ruediger, Edward, Tremblay, François, Posy, Shana L., Guarino, Victor R., Richter, Jeremy M., Li, Jianqing, Gupta, Anuradha, Vetrichelvan, Muthalagu, Balapragalathan, T. J., Mathur, Arvind, Hua, Ji, Callejo, Mario, Guay, Jocelyne, Sum, Chi Shing, Cvijic, Mary Ellen, Watson, Carol, Wong, Pancras, Yang, Jing, Bouvier, Michel, Gordon, David A., Wexler, Ruth R., Marinier, Anne
Published in Journal of medicinal chemistry (14.07.2022)
Published in Journal of medicinal chemistry (14.07.2022)
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Journal Article
Abstract 1869: Novel TNFR2 antibodies to overcome T cell exhaustion and suppressive tumor microenvironment
Sum, Chi Shing, Danton, Makenzie, hu, Qii, Pritsker, Alla, Lin, Ray, Yu, Raymond, Chen, Kevin, Tang, Fangqiang, Pohl, Thomas, Wallner, Samantha, Hassan, Ahmed, Lu, Huarui, Huang, Haichun, Pei, James, Liu, Zhong, Li, Han, Lei, Ming
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
GPCR profiling: from hits to leads and from genotype to phenotype
Cvijic, Mary Ellen, Sum, Chi Shing, Alt, Andrew, Zhang, Litao
Published in Drug discovery today. Technologies (01.11.2015)
Published in Drug discovery today. Technologies (01.11.2015)
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Journal Article
Synthesis and SAR of 1,2,3,4-Tetrahydroisoquinoline-Based CXCR4 Antagonists
Wilson, Robert J, Jecs, Edgars, Miller, Eric J, Nguyen, Huy H, Tahirovic, Yesim A, Truax, Valarie M, Kim, Michelle B, Kuo, Katie M, Wang, Tao, Sum, Chi Shing, Cvijic, Mary E, Paiva, Anthony A, Schroeder, Gretchen M, Wilson, Lawrence J, Liotta, Dennis C
Published in ACS medicinal chemistry letters (11.01.2018)
Published in ACS medicinal chemistry letters (11.01.2018)
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Journal Article
Evidence for Classical Cholinergic Toxicity Associated with Selective Activation of M1 Muscarinic Receptors
Alt, Andrew, Pendri, Annapurna, Bertekap, Jr, Robert L, Li, Guo, Benitex, Yulia, Nophsker, Michelle, Rockwell, Kristin L, Burford, Neil T, Sum, Chi Shing, Chen, Jing, Herbst, John J, Ferrante, Meredith, Hendricson, Adam, Cvijic, Mary Ellen, Westphal, Ryan S, O'Connell, Jonathan, Banks, Martyn, Zhang, Litao, Gentles, Robert G, Jenkins, Susan, Loy, James, Macor, John E
Published in The Journal of pharmacology and experimental therapeutics (01.02.2016)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2016)
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Journal Article
Cholesterol as a determinant of cooperativity in the M 2 muscarinic cholinergic receptor
Colozo, Alejandro T., Park, Paul S.-H., Sum, Chi Shing, Pisterzi, Luca F., Wells, James W.
Published in Biochemical pharmacology (15.07.2007)
Published in Biochemical pharmacology (15.07.2007)
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Journal Article
Discovery of novel agonists and antagonists of the free fatty acid receptor one (FFAR1) using virtual screening
Tikhonova, Irina G., Sum, Chi Shing, Neumann, Susanne, Engel, Stanislav, Raaka, Bruce M., Costanzi, Stefano, Gershengorn, Marvin C.
Published in Journal of medicinal chemistry (15.01.2008)
Published in Journal of medicinal chemistry (15.01.2008)
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Journal Article