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Effect of food on the bioavailability and tolerability of the JAK2-selective inhibitor fedratinib (SAR302503): Results from two phase I studies in healthy volunteers
Zhang, Meng, Xu, Christine, Ma, Lei, Shamiyeh, Elias, Yin, Jianyun, von Moltke, Lisa L., Smith, William B.
Published in Clinical pharmacology in drug development (01.07.2015)
Published in Clinical pharmacology in drug development (01.07.2015)
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Prediction of Transporter‐Mediated Drug‐Drug Interactions for Baricitinib
Posada, Maria M., Cannady, Ellen A., Payne, Christopher D., Zhang, Xin, Bacon, James A., Pak, Y. Anne, Higgins, J. William, Shahri, Nazila, Hall, Stephen D., Hillgren, Kathleen M.
Published in Clinical and translational science (01.11.2017)
Published in Clinical and translational science (01.11.2017)
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Efficacy and safety of JAK inhibitors in patients aged > 60 years with moderate-to-severe atopic dermatitis: a 52-week multicenter, real-life study—IL AD (Italian Landscape Atopic Dermatitis)
Potestio, Luca, Patruno, Cataldo, Narcisi, Alessandra, Costanzo, Antonio, Ibba, Luciano, Gargiulo, Luigi, Malagoli, Piergiorgio, Ortoncelli, Michela, Ribero, Simone, Mastorino, Luca, Leo, Francesco, Ferrucci, Silvia Mariel, Angileri, Luisa, Barei, Francesca, Stingeni, Luca, Hansel, Katharina, Sciarrone, Claudio, Girolomoni, Giampiero, Maurelli, Martina, Foti, Caterina, Tirone, Benedetta, Balato, Anna, Esposito, Maria, Paolino, Giovanni, Mercuri, Santo Raffaele, Pezzolo, Elena, Savoia, Paola, Brescia, Claudio, Napolitano, Maddalena
Published in Archives of Dermatological Research (23.05.2025)
Published in Archives of Dermatological Research (23.05.2025)
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An innovative phase I study in healthy subjects to determine the mass balance, elimination, metabolism, and absolute bioavailability of mitapivat
Prakash, Chandra, Mangus, Heidi, Yan, Yan, Yang, Hua, Iyer, Varsha
Published in Clinical and translational science (01.10.2023)
Published in Clinical and translational science (01.10.2023)
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Effects of repeated oral doses of ketoconazole on a sequential ascending single oral dose of fedratinib in healthy subjects
Ogasawara, Ken, Xu, Christine, Kanamaluru, Vanaja, Palmisano, Maria, Krishna, Gopal
Published in Cancer chemotherapy and pharmacology (01.05.2020)
Published in Cancer chemotherapy and pharmacology (01.05.2020)
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Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Nebulized Sodium Nitrite (AIR001) Following Repeat-Dose Inhalation in Healthy Subjects
Rix, Peter J., Vick, Andrew, Attkins, Neil J., Barker, Geoffrey E., Bott, Adrian W., Alcorn, Harry, Gladwin, Mark T., Shiva, Sruti, Bradley, Stephen, Hussaini, Azra, Hoye, William L., Parsley, Ed L., Masamune, Hiroko
Published in Clinical pharmacokinetics (01.03.2015)
Published in Clinical pharmacokinetics (01.03.2015)
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A reduction of 3 g/day from a usual 9 g/day salt diet improves endothelial function and decreases endothelin-1 in a randomised cross_over study in normotensive overweight and obese subjects
Dickinson, Kacie M., Clifton, Peter M., Keogh, Jennifer B.
Published in Atherosclerosis (01.03.2014)
Published in Atherosclerosis (01.03.2014)
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Effect of Low- and High-Fat Meals on the Pharmacokinetics of Venetoclax, a Selective First-in-Class BCL-2 Inhibitor
Salem, Ahmed Hamed, Agarwal, Suresh K, Dunbar, Martin, Nuthalapati, Silpa, Chien, David, Freise, Kevin J, Wong, Shekman L
Published in Journal of clinical pharmacology (01.11.2016)
Published in Journal of clinical pharmacology (01.11.2016)
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Can a Selective PPARγ Modulator Improve Glycemic Control in Patients With Type 2 Diabetes With Fewer Side Effects Compared With Pioglitazone?
DePaoli, Alex M., Higgins, Linda S., Henry, Robert R., Mantzoros, Christos, Dunn, Fredrick L.
Published in Diabetes care (01.07.2014)
Published in Diabetes care (01.07.2014)
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The effect of a selective CXCR2 antagonist (AZD5069) on human blood neutrophil count and innate immune functions
Jurcevic, Stipo, Humfrey, Charles, Uddin, Mohib, Warrington, Steve, Larsson, Bengt, Keen, Christina
Published in British journal of clinical pharmacology (01.12.2015)
Published in British journal of clinical pharmacology (01.12.2015)
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Pharmacokinetic Interactions Between Tegoprazan and the Combination of Clarithromycin, Amoxicillin and Bismuth in Healthy Chinese Subjects: An Open-Label, Single-Center, Multiple-Dosage, Self-Controlled, Phase I Trial
Du, Yujing, Yu, Lixiu, Deng, Bin, Li, Qinying, Hu, Junrui, Li, Linjie, Xu, Yusen, Song, Liangwei, Xie, Fang, Wang, Yinghui, Chen, Yuhao, Liu, Chengxin, Zhai, Xuejia, Lu, Yongning
Published in Clinical drug investigation (01.05.2024)
Published in Clinical drug investigation (01.05.2024)
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Pharmacokinetics of Fosamprenavir plus Ritonavir in Human Immunodeficiency Virus Type 1-Infected Adult Subjects with Hepatic Impairment
PEREZ-ELIAS, Maria J, LARROUSSE MORELLON, Maria, YU LOU, MARY BETH WIRE, ORTEGA, Enrique, HERNANDEZ-QUERO, José, RODRIGUEZ-TORRES, Maribel, CLOTET, Bonaventura, FELIZARTA, Franco, GUTIERREZ, Felix, PINEDA, Juan A, NICHOLS, Garrett
Published in Antimicrobial Agents and Chemotherapy (01.12.2009)
Published in Antimicrobial Agents and Chemotherapy (01.12.2009)
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Anti-Aβ agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis
Lu, Liming, Zheng, Xiaoyan, Wang, Shengwen, Tang, Chunzhi, Zhang, Yuqing, Yao, Gaolei, Zeng, Jingchun, Ge, Shuqi, Wen, Hao, Xu, Mingzhu, Guyatt, Gordon, Xu, Nenggui
Published in Journal of neurology, neurosurgery and psychiatry (01.12.2020)
Published in Journal of neurology, neurosurgery and psychiatry (01.12.2020)
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Nonsteroidal anti-inflammatory drugs and upper and lower gastrointestinal mucosal damage
Sostres, Carlos, Gargallo, Carla J, Lanas, Angel
Published in Arthritis research & therapy (01.01.2013)
Published in Arthritis research & therapy (01.01.2013)
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A randomised, placebo-controlled study of omipalisib (PI3K/mTOR) in idiopathic pulmonary fibrosis
Lukey, Pauline T., Harrison, Stephen A., Yang, Shuying, Man, Yim, Holman, Beverley F., Rashidnasab, Alaleh, Azzopardi, Gabrielle, Grayer, Michael, Simpson, Juliet K., Bareille, Philippe, Paul, Lyn, Woodcock, Hannah V., Toshner, Richard, Saunders, Peter, Molyneaux, Philip L., Thielemans, Kris, Wilson, Frederick J., Mercer, Paul F., Chambers, Rachel C., Groves, Ashley M., Fahy, William A., Marshall, Richard P., Maher, Toby M.
Published in The European respiratory journal (01.03.2019)
Published in The European respiratory journal (01.03.2019)
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Effects of Food, Gastric Acid Reduction, and Strong CYP3A Induction on the Pharmacokinetics of Tasurgratinib, a Novel Selective Fibroblast Growth Factor Receptor Inhibitor
Nomoto, Maiko, Hasunuma, Tomoko, Cai, Cuiyuan, Suzuki, Ippei, Mikubo, Ayano, Funasaka, Setsuo, Otake, Yohei, Nakai, Kenya, Yasuda, Sanae
Published in Journal of clinical pharmacology (01.12.2024)
Published in Journal of clinical pharmacology (01.12.2024)
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