Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
Byrd, John C, Furman, Richard R, Coutre, Steven E, Flinn, Ian W, Burger, Jan A, Blum, Kristie A, Grant, Barbara, Sharman, Jeff P, Coleman, Morton, Wierda, William G, Jones, Jeffrey A, Zhao, Weiqiang, Heerema, Nyla A, Johnson, Amy J, Sukbuntherng, Juthamas, Chang, Betty Y, Clow, Fong, Hedrick, Eric, Buggy, Joseph J, James, Danelle F, O'Brien, Susan
Published in The New England journal of medicine (04.07.2013)
Published in The New England journal of medicine (04.07.2013)
Get full text
Journal Article
Bruton Tyrosine Kinase Inhibitor Ibrutinib (PCI-32765) Has Significant Activity in Patients With Relapsed/Refractory B-Cell Malignancies
ADVANI, Ranjana H, BUGGY, Joseph J, SUKBUNTHERNG, Juthamas, IZUMI, Raquel, HAMDY, Ahmed, HEDRICK, Eric, FOWLER, Nathan H, SHARMAN, Jeff P, SMITH, Sonali M, BOYD, Thomas E, GRANT, Barbara, KOLIBABA, Kathryn S, FURMAN, Richard R, RODRIGUEZ, Sara, CHANG, Betty Y
Published in Journal of clinical oncology (01.01.2013)
Published in Journal of clinical oncology (01.01.2013)
Get full text
Journal Article
The effect of Bruton's tyrosine kinase (BTK) inhibitors on collagen‐induced platelet aggregation, BTK, and tyrosine kinase expressed in hepatocellular carcinoma (TEC)
Chen, Jun, Kinoshita, Taisei, Gururaja, Tarikere, Sukbuntherng, Juthamas, James, Danelle, Lu, Daniel, Whang, Jennifer, Versele, Matthias, Chang, Betty Y.
Published in European journal of haematology (01.11.2018)
Published in European journal of haematology (01.11.2018)
Get full text
Journal Article
Population pharmacokinetics and pharmacodynamics of gabapentin after administration of gabapentin enacarbil
Lal, Ritu, Sukbuntherng, Juthamas, Luo, Wendy, Tovera, James, Lassauzet, Marie Liesse, Cundy, Kenneth C
Published in Journal of clinical pharmacology (01.01.2013)
Published in Journal of clinical pharmacology (01.01.2013)
Get more information
Journal Article
Arbaclofen Placarbil, a Novel R-Baclofen Prodrug: Improved Absorption, Distribution, Metabolism, and Elimination Properties Compared with R-Baclofen
Lal, Ritu, Sukbuntherng, Juthamas, Tai, Ezra H L, Upadhyay, Shubhra, Yao, Fenmei, Warren, Mark S, Luo, Wendy, Bu, Lin, Nguyen, Son, Zamora, Jeanelle, Peng, Ge, Dias, Tracy, Bao, Ying, Ludwikow, Maria, Phan, Thu, Scheuerman, Randall A, Yan, Hui, Gao, Mark, Wu, Quincey Q, Annamalai, Thamil, Raillard, Stephen P, Koller, Kerry, Gallop, Mark A, Cundy, Kenneth C
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
Get full text
Journal Article
Clinical Pharmacokinetics of Gabapentin After Administration of Gabapentin Enacarbil Extended-Release Tablets in Patients With Varying Degrees of Renal Function Using Data From an Open-Label, Single-Dose Pharmacokinetic Study
Lal, Ritu, PhD, Sukbuntherng, Juthamas, PhD, Luo, Wendy, MS, Chen, Dan, MD, PhD, Blumenthal, Robin, PhD, Ho, Judy, BS, Cundy, Kenneth C., PhD
Published in Clinical therapeutics (2012)
Published in Clinical therapeutics (2012)
Get full text
Journal Article
Single- and multiple-dose disposition kinetics of sunitinib malate, a multitargeted receptor tyrosine kinase inhibitor: comparative plasma kinetics in non-clinical species
Haznedar, Joshua Ö., Patyna, Shem, Bello, Carlo L., Peng, Geoffrey W., Speed, William, Yu, Xiaoming, Zhang, Qingling, Sukbuntherng, Juthamas, Sweeny, David J., Antonian, Lida, Wu, Ellen Y.
Published in Cancer chemotherapy and pharmacology (01.09.2009)
Published in Cancer chemotherapy and pharmacology (01.09.2009)
Get full text
Journal Article
SU14813: a novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activity
Patyna, Shem, Laird, A Douglas, Mendel, Dirk B, O'farrell, Anne-Marie, Liang, Chris, Guan, Huiping, Vojkovsky, Tomas, Vasile, Stefan, Wang, Xueyan, Chen, Jeffrey, Grazzini, Maren, Yang, Cheng Y, Haznedar, Joshua O, Sukbuntherng, Juthamas, Zhong, Wei-Zhu, Cherrington, Julie M, Hu-Lowe, Dana
Published in Molecular cancer therapeutics (01.07.2006)
Published in Molecular cancer therapeutics (01.07.2006)
Get full text
Journal Article
Pharmacokinetics and tolerability of single escalating doses of gabapentin enacarbil: A randomized-sequence, double-blind, placebo-controlled crossover study in healthy volunteers
Lal, Ritu, PhD, Sukbuntherng, Juthamas, PhD, Luo, Wendy, MS, Chen, Dan, MD, PhD, Vu, Amanda, MS, Tovera, James, BS, Cundy, Kenneth C., PhD
Published in Clinical therapeutics (01.08.2009)
Published in Clinical therapeutics (01.08.2009)
Get full text
Journal Article
Absorption, metabolism, and excretion of oral ¹⁴C radiolabeled ibrutinib: an open-label, phase I, single-dose study in healthy men
Scheers, Ellen, Leclercq, Laurent, de Jong, Jan, Bode, Nini, Bockx, Marc, Laenen, Aline, Cuyckens, Filip, Skee, Donna, Murphy, Joe, Sukbuntherng, Juthamas, Mannens, Geert
Published in Drug metabolism and disposition (01.02.2015)
Published in Drug metabolism and disposition (01.02.2015)
Get full text
Journal Article
Adherence To The Ibrutinib 420 mg Dose Administered To Patients With Previously Treated CLL
Burger, Jan A., MD, PhD, Barr, Paul M., MD, Brown, Jennifer R., MD, PhD, Hillmen, Peter, MB ChB, PhD, O'Brien, Susan, MD, Barrientos, Jacqueline C., MD, Reddy, Nishitha M., MBBS, MScl, Coutre, Steven, MD, Mulligan, Stephen P., MBBS, MD, FRACP, FRCPA, Jaeger, Ulrich, MD, Furman, Richard R., MD, Cymbalista, Florence, MD, Montillo, Marco, MD, Dearden, Claire, MD, Robak, Tadeusz, MD, PhD, Carol Moreno, MD, Pagel, John, MD, PhD, Suzuki, Samuel, MS, MBA, Sukbuntherng, Juthamas, PhD, Cole, George, MD, James, Danelle F., MD, MAS, Byrd, John C., MD
Published in Clinical lymphoma, myeloma and leukemia (01.09.2015)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2015)
Get full text
Journal Article
Distribution, metabolism, and excretion of the anti-angiogenic compound SU5416
Ye, Christine, Sweeny, David, Sukbuntherng, Juthamas, Zhang, Qingling, Tan, Weiwei, Wong, Simon, Madan, Ajay, Ogilvie, Brian, Parkinson, Andrew, Antonian, Lida
Published in Toxicology in vitro (01.03.2006)
Published in Toxicology in vitro (01.03.2006)
Get full text
Journal Article
Evaluation of antitumor properties of novel saframycin analogs in vitro and in vivo
Spencer, Jeffrey R., Sendzik, Martin, Oeh, Jason, Sabbatini, Peter, Dalrymple, Stacie A., Magill, Catherine, Kim, Hyunjin M., Zhang, Penglie, Squires, Neil, Moss, Katherine G., Sukbuntherng, Juthamas, Graupe, Doris, Eksterowicz, John, Young, Peter R., Myers, Andrew G., Green, Michael J.
Published in Bioorganic & medicinal chemistry letters (15.09.2006)
Published in Bioorganic & medicinal chemistry letters (15.09.2006)
Get full text
Journal Article
Ibrutinib does not prolong the corrected QT interval in healthy subjects: results from a thorough QT study
de Jong, Jan, Hellemans, Peter, Jiao, James Juhui, Huang, Yuhan, Mesens, Sofie, Sukbuntherng, Juthamas, Ouellet, Daniele
Published in Cancer chemotherapy and pharmacology (01.12.2017)
Published in Cancer chemotherapy and pharmacology (01.12.2017)
Get full text
Journal Article
Impact of ibrutinib dose adherence on therapeutic efficacy in patients with previously treated CLL/SLL
Barr, Paul M., Brown, Jennifer R., Hillmen, Peter, O'Brien, Susan, Barrientos, Jacqueline C., Reddy, Nishitha M., Coutre, Steven, Mulligan, Stephen P., Jaeger, Ulrich, Furman, Richard R., Cymbalista, Florence, Montillo, Marco, Dearden, Claire, Robak, Tadeusz, Moreno, Carol, Pagel, John M., Burger, Jan A., Suzuki, Samuel, Sukbuntherng, Juthamas, Cole, George, James, Danelle F., Byrd, John C.
Published in Blood (11.05.2017)
Published in Blood (11.05.2017)
Get full text
Journal Article
The effect of food on the pharmacokinetics of oral ibrutinib in healthy participants and patients with chronic lymphocytic leukemia
de Jong, Jan, Sukbuntherng, Juthamas, Skee, Donna, Murphy, Joe, O’Brien, Susan, Byrd, John C., James, Danelle, Hellemans, Peter, Loury, David J., Jiao, Juhui, Chauhan, Vijay, Mannaert, Erik
Published in Cancer chemotherapy and pharmacology (01.05.2015)
Published in Cancer chemotherapy and pharmacology (01.05.2015)
Get full text
Journal Article
Stable isotope‐labelled intravenous microdose for absolute bioavailability and effect of grapefruit juice on ibrutinib in healthy adults
Vries, Ronald, Smit, Johan W., Hellemans, Peter, Jiao, James, Murphy, Joseph, Skee, Donna, Snoeys, Jan, Sukbuntherng, Juthamas, Vliegen, Maarten, Zwart, Loeckie, Mannaert, Erik, Jong, Jan
Published in British journal of clinical pharmacology (01.02.2016)
Published in British journal of clinical pharmacology (01.02.2016)
Get full text
Journal Article
A Randomized, Double-Blind, Phase 3 Safety and Efficacy Study of Ridinilazole Versus Vancomycin for Treatment of Clostridioides difficile Infection: Clinical Outcomes With Microbiome and Metabolome Correlates of Response
Okhuysen, Pablo C, Ramesh, Mayur S, Louie, Thomas, Kiknadze, Nino, Torre-Cisneros, Julian, de Oliveira, Claudia Murta, Van Steenkiste, Christophe, Stychneuskaya, Alena, Garey, Kevin W, Garcia-Diaz, Julia, Li, Jianling, Duperchy, Esther, Chang, Betty Y, Sukbuntherng, Juthamas, Montoya, Jose G, Styles, Lori, Clow, Fong, James, Danelle, Dubberke, Erik R, Wilcox, Mark
Published in Clinical infectious diseases (02.02.2024)
Published in Clinical infectious diseases (02.02.2024)
Get full text
Journal Article