H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma
Joshi, Jaya Julie, Coffey, Heather, Corcoran, Erik, Tsai, Jennifer, Huang, Chia-Ling, Ichikawa, Kana, Prajapati, Sudeep, Hao, Ming-Hong, Bailey, Suzanna, Wu, Jeremy, Rimkunas, Victoria, Karr, Craig, Subramanian, Vanitha, Kumar, Pavan, MacKenzie, Crystal, Hurley, Raelene, Satoh, Takashi, Yu, Kun, Park, Eunice, Rioux, Nathalie, Kim, Amy, Lai, Weidong G, Yu, Lihua, Zhu, Ping, Buonamici, Silvia, Larsen, Nicholas, Fekkes, Peter, Wang, John, Warmuth, Markus, Reynolds, Dominic J, Smith, Peter G, Selvaraj, Anand
Published in Cancer research (Chicago, Ill.) (15.12.2017)
Published in Cancer research (Chicago, Ill.) (15.12.2017)
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Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex
Teng, Teng, Tsai, Jennifer Hc, Puyang, Xiaoling, Seiler, Michael, Peng, Shouyong, Prajapati, Sudeep, Aird, Daniel, Buonamici, Silvia, Caleb, Benjamin, Chan, Betty, Corson, Laura, Feala, Jacob, Fekkes, Peter, Gerard, Baudouin, Karr, Craig, Korpal, Manav, Liu, Xiang, T Lowe, Jason, Mizui, Yoshiharu, Palacino, James, Park, Eunice, Smith, Peter G, Subramanian, Vanitha, Wu, Zhenhua Jeremy, Zou, Jian, Yu, Lihua, Chicas, Agustin, Warmuth, Markus, Larsen, Nicholas, Zhu, Ping
Published in Nature communications (25.05.2017)
Published in Nature communications (25.05.2017)
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Ribonucleocapsid Formation of Severe Acute Respiratory Syndrome Coronavirus through Molecular Action of the N-Terminal Domain of N Protein
KUMAR SINGH SAIKATENDU, JOSEPH, Jeremiah S, SUBRAMANIAN, Vanitha, NEUMAN, Benjamin W, BUCHMEIER, Michael J, STEVENS, Raymond C, KUHN, Peter
Published in Journal of Virology (01.04.2007)
Published in Journal of Virology (01.04.2007)
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Author Correction: Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer
Korpal, Manav, Puyang, Xiaoling, Wu, Zhenhua Jeremy, Seiler, Roland, Furman, Craig, Oo, Htoo Zarni, Seiler, Michael, Irwin, Sean, Subramanian, Vanitha, Joshi, Jaya Julie, Wang, Chris K, Rimkunas, Victoria, Tortora, Davide, Yang, Hua, Kumar, Namita, Kuznetsov, Galina, Matijevic, Mark, Chow, Jesse, Kumar, Pavan, Zou, Jian, Feala, Jacob, Corson, Laura, Henry, Ryan, Selvaraj, Anand, Davis, Allison, Bloudoff, Kristjan, Douglas, James, Kiss, Bernhard, Roberts, Morgan, Fazli, Ladan, Black, Peter C, Fekkes, Peter, Smith, Peter G, Warmuth, Markus, Yu, Lihua, Hao, Ming-Hong, Larsen, Nicholas, Daugaard, Mads, Zhu, Ping
Published in Nature communications (04.06.2019)
Published in Nature communications (04.06.2019)
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Crystal Structure of Nonstructural Protein 10 from the Severe Acute Respiratory Syndrome Coronavirus Reveals a Novel Fold with Two Zinc-Binding Motifs
JOSEPH, Jeremiah S, KUMAR SINGH SAIKATENDU, STEVENS, Raymond C, KUHN, Peter, SUBRAMANIAN, Vanitha, NEUMAN, Benjamin W, BROOUN, Alexei, GRIFFITH, Mark, MOY, Kin, YADAV, Maneesh K, VELASQUEZ, Jeffrey, BUCHMEIER, Michael J
Published in Journal of Virology (01.08.2006)
Published in Journal of Virology (01.08.2006)
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Journal Article
Crystal Structure of a Monomeric Form of Severe Acute Respiratory Syndrome Coronavirus Endonuclease nsp15 Suggests a Role for Hexamerization as an Allosteric Switch
Joseph, Jeremiah S, Saikatendu, Kumar Singh, Subramanian, Vanitha, Neuman, Benjamin W, Buchmeier, Michael J, Stevens, Raymond C, Kuhn, Peter
Published in Journal of Virology (01.06.2007)
Published in Journal of Virology (01.06.2007)
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Journal Article
Nuclear Magnetic Resonance Structure of the N-Terminal Domain of Nonstructural Protein 3 from the Severe Acute Respiratory Syndrome Coronavirus
SERRANO, Pedro, JOHNSON, Margaret A, STEVENS, Raymond C, KUHN, Peter, WÜTHRICH, Kurt, ALMEIDA, Marcius S, HORST, Reto, HERRMANN, Torsten, JOSEPH, Jeremiah S, NEUMAN, Benjamin W, SUBRAMANIAN, Vanitha, SAIKATENDU, Kumar S, BUCHMEIER, Michael J
Published in Journal of Virology (01.11.2007)
Published in Journal of Virology (01.11.2007)
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Journal Article
Identification of a PCSK9-LDLR disruptor peptide with in vivo function
Brousseau, Margaret E., Clairmont, Kevin B., Spraggon, Glen, Flyer, Alec N., Golosov, Andrei A., Grosche, Philipp, Amin, Jakal, Andre, Jerome, Burdick, Debra, Caplan, Shari, Chen, Guanjing, Chopra, Raj, Ames, Lisa, Dubiel, Diana, Fan, Li, Gattlen, Raphael, Kelly-Sullivan, Dawn, Koch, Alexander W., Lewis, Ian, Li, Jingzhou, Liu, Eugene, Lubicka, Danuta, Marzinzik, Andreas, Nakajima, Katsumasa, Nettleton, David, Ottl, Johannes, Pan, Meihui, Patel, Tajesh, Perry, Lauren, Pickett, Stephanie, Poirier, Jennifer, Reid, Patrick C., Pelle, Xavier, Seepersaud, Mohindra, Subramanian, Vanitha, Vera, Victoria, Xu, Mei, Yang, Lihua, Yang, Qing, Yu, Jinghua, Zhu, Guoming, Monovich, Lauren G.
Published in Cell chemical biology (17.02.2022)
Published in Cell chemical biology (17.02.2022)
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Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer
Korpal, Manav, Puyang, Xiaoling, Jeremy Wu, Zhenhua, Seiler, Roland, Furman, Craig, Oo, Htoo Zarni, Seiler, Michael, Irwin, Sean, Subramanian, Vanitha, Julie Joshi, Jaya, Wang, Chris K, Rimkunas, Victoria, Tortora, Davide, Yang, Hua, Kumar, Namita, Kuznetsov, Galina, Matijevic, Mark, Chow, Jesse, Kumar, Pavan, Zou, Jian, Feala, Jacob, Corson, Laura, Henry, Ryan, Selvaraj, Anand, Davis, Allison, Bloudoff, Kristjan, Douglas, James, Kiss, Bernhard, Roberts, Morgan, Fazli, Ladan, Black, Peter C, Fekkes, Peter, Smith, Peter G, Warmuth, Markus, Yu, Lihua, Hao, Ming-Hong, Larsen, Nicholas, Daugaard, Mads, Zhu, Ping
Published in Nature communications (24.07.2017)
Published in Nature communications (24.07.2017)
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Clearance of plasma PCSK9 via the asialoglycoprotein receptor mediated by heterobifunctional ligands
Bagdanoff, Jeffrey T., Smith, Thomas M., Allan, Martin, O’Donnell, Peter, Nguyen, Zachary, Moore, Elizabeth A., Baird, Jason, Wang, Shuangxi, Subramanian, Vanitha, Tigani, Bruno, Nettleton, David O., Monovich, Lauren G., Lewis, Ian, Flyer, Alec N., Granda, Brian, Blankenship, John W., Barnes-Seeman, David, Clairmont, Kevin B.
Published in Cell chemical biology (19.01.2023)
Published in Cell chemical biology (19.01.2023)
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Abstract 10516: Identification of a PCSK9-LDLR Disruptor Macrocycle with in vivo Function
Brousseau, Margaret E, Clairmont, Kevin B, Spraggon, Glen, Flyer, Alec N, Golosov, Andrei A, Grosche, Philipp, André, Jérôme, Caplan, Shari, Chen, Guanjing, Fan, Li, Gattlen, Raphael, Koch, Alexander, Lewis, Ian, Li, Jingzhou, Liu, Eugene, Lubicka, Danuta, Marzinzik, Andreas, Nakajima, Katsumasa, Nettleton, David, Ottl, Johannes, Pan, Meihui, Patel, Tajesh, Pickett, Stephanie, Poirier, Jennifer, Reid, Patrick C, Pelle, Xavier, Subramanian, Vanitha, Vera, Victoria, Xu, Mei, Yang, Lihua, Yang, Qing, yu, jinghua, Zhu, Guoming, Monovich, Lauren G
Published in Circulation (New York, N.Y.) (16.11.2021)
Published in Circulation (New York, N.Y.) (16.11.2021)
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Abstract 126: A chemogenomic approach reveals the action of splicing modulators at the branch point adenosine binding pocket defined by the PHF5A/SF3b complex
Teng, Teng, Tsai, Jennifer, Puyang, Xiaoling, Seiler, Michael, Peng, Shouyong, Aird, Daniel, Buonamici, Silvia, Caleb, Benjamin, Chan, Betty, Corson, Laura, Feala, Jacob, Fekkes, Peter, Karr, Craig, Korpal, Manav, Mizui, Yoshiharu, Park, Eunice, Palacino, James, Smith, Peter, Subramanian, Vanitha, Wu, Jeremy, Yu, Lihua, Chicas, Agustin, Warmuth, Markus, Larsen, Nicholas, Zhu, Ping
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Structural Basis of Severe Acute Respiratory Syndrome Coronavirus ADP-Ribose-1″-Phosphate Dephosphorylation by a Conserved Domain of nsP3
Saikatendu, Kumar Singh, Joseph, Jeremiah S., Subramanian, Vanitha, Clayton, Tom, Griffith, Mark, Moy, Kin, Velasquez, Jeffrey, Neuman, Benjamin W., Buchmeier, Michael J., Stevens, Raymond C., Kuhn, Peter
Published in Structure (London) (01.11.2005)
Published in Structure (London) (01.11.2005)
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Abstract DDT01-04: Discovery and development of H3B-6545: A novel, oral, selective estrogen receptor covalent antagonist (SERCA) for the treatment of breast cancer
Smith, Peter G., Puyang, Xiaoling, Furman, Craig, Zheng, Guo Zhu, Banka, Deepti, Thomas, Michael, Subramanian, Vanitha, Irwin, Sean, Larsen, Nicholas, Caleb, Benjamin, Karr, Craig, Wu, Jeremy, O’Shea, Morgan, Yang, Joyce, Davis, Allison, Kim, Amy, Rioux, Nathalie, Rimkunas, Victoria, Yao, Huilan, MacKenzie, Crystal, Kumar, Pavan, Smith, Sherri, Eckley, Sean, Hart, Andrew, Lai, George, Rowbottom, Christopher, Fekkes, Peter, Buonamici, Silvia, Reynolds, Dominic, Yu, Lihua, Sahmoud, Tarek, Warmuth, Markus, Mitchell, Lorna, Zhu, Ping, Korpal, Manav
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERα WT and ERα MUT Breast Cancer
Puyang, Xiaoling, Furman, Craig, Zheng, Guo Zhu, Wu, Zhenhua J, Banka, Deepti, Aithal, Kiran, Agoulnik, Sergei, Bolduc, David M, Buonamici, Silvia, Caleb, Benjamin, Das, Subhasree, Eckley, Sean, Fekkes, Peter, Hao, Ming-Hong, Hart, Andrew, Houtman, René, Irwin, Sean, Joshi, Jaya J, Karr, Craig, Kim, Amy, Kumar, Namita, Kumar, Pavan, Kuznetsov, Galina, Lai, Weidong G, Larsen, Nicholas, Mackenzie, Crystal, Martin, Lesley-Ann, Melchers, Diana, Moriarty, Alyssa, Nguyen, Tuong-Vi, Norris, John, O'Shea, Morgan, Pancholi, Sunil, Prajapati, Sudeep, Rajagopalan, Sujatha, Reynolds, Dominic J, Rimkunas, Victoria, Rioux, Nathalie, Ribas, Ricardo, Siu, Amy, Sivakumar, Sasirekha, Subramanian, Vanitha, Thomas, Michael, Vaillancourt, Frédéric H, Wang, John, Wardell, Suzanne, Wick, Michael J, Yao, Shihua, Yu, Lihua, Warmuth, Markus, Smith, Peter G, Zhu, Ping, Korpal, Manav
Published in Cancer discovery (01.09.2018)
Published in Cancer discovery (01.09.2018)
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Crystal structure of a monomeric form of severe acute respiratory syndrome coronavirus endonuclease nspl5 suggests a role for hexamerization as an allosteric switch
JOSEPH, Jeremiah S, KUMAR SINGH SAIKATENDU, SUBRAMANIAN, Vanitha, NEUMAN, Benjamin W, BUCHMEIER, Michael J, STEVENS, Raymond C, KUHN, Peter
Published in Journal of virology (2007)
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Published in Journal of virology (2007)
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