Discovery of a small molecule RXFP3/4 agonist that increases food intake in rats upon acute central administration
DeChristopher, Brian, Park, Soo-Hee, Vong, Linh, Bamford, Derek, Cho, Hyun-Hee, Duvadie, Rohit, Fedolak, Allison, Hogan, Christopher, Honda, Toshiyuki, Pandey, Pramod, Rozhitskaya, Olga, Su, Liansheng, Tomlinson, Elizabeth, Wallace, Iain
Published in Bioorganic & medicinal chemistry letters (15.04.2019)
Published in Bioorganic & medicinal chemistry letters (15.04.2019)
Get full text
Journal Article
A Phenotypic Screen Identifies Calcium Overload as a Key Mechanism of β-Cell Glucolipotoxicity
Vogel, Jennifer, Yin, Jianning, Su, Liansheng, Wang, Sharon X, Zessis, Richard, Fowler, Sena, Chiu, Chun-Hao, Wilson, Aaron C, Chen, Amy, Zecri, Frederic, Turner, Gordon, Smith, Thomas M, DeChristopher, Brian, Xing, Heming, Rothman, Deborah M, Cai, Xinming, Berdichevsky, Alina
Published in Diabetes (New York, N.Y.) (01.05.2020)
Published in Diabetes (New York, N.Y.) (01.05.2020)
Get full text
Journal Article
Cyclic tetramer compounds as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders
Dechristopher, Brian Addison, Yang, Lihua, Zheng, Rui, Grosche, Philipp, Patel, Tajesh Jayprakash, Briner, Karin, Liu, Eugene Yuejin, Monovich, Lauren Gilchrist, Mao, Justin Yik Ching, Su, Liansheng, Flyer, Alec Nathanson, Golosov, Andrei Alexandrovich
Year of Publication 14.11.2023
Get full text
Year of Publication 14.11.2023
Patent
Cyclic tetramer compounds as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders
Yang, Lihua, Grosche, Philipp, Briner, Karin, Mao, Justin Yik Ching, Su, Liansheng, Dechristopher, Brian Addison, Zheng, Rui, Patel, Tajesh Jayprakash, Liu, Eugene Yuejin, Monovich, Lauren Gilchrist, Flyer, Alec Nathanson, Sanchez, Carina Cristina, Golosov, Andrei Alexandrovich
Year of Publication 08.06.2021
Get full text
Year of Publication 08.06.2021
Patent
Derivados de benzo[d][1,3]dioxol como activadores del receptor glp1 para tratamiento de obesidad
Daniel SMITH, Matthew CARSON, Troy SMITH, Ping ZHANG, Ming QIAN, Lihua YANG, Liansheng SU, Thomas CAYA, Lara CZABANIUK, Chung-Yeh WU, Chun ZHANG, Martin ALLAN, Xilin ZHOU
Year of Publication 03.05.2024
Get full text
Year of Publication 03.05.2024
Patent
COMPUESTOS TETRÁMEROS CÍCLICOS COMO INHIBIDORES DE PROPROTEÍNA CONVERTASA SUBTILISINA/KEXINA TIPO 9 (PCSK9) PARA EL TRATAMIENTO DE TRASTORNOS METABÓLICOS
Yang, Lihua, Grosche, Philipp, Briner, Karin, Mao, Justin Yik Ching, Su, Liansheng, Dechristopher, Brian Addison, Zheng, Rui, Patel, Tajesh Jayprakash, Liu, Eugene Yuejin, Monovich, Lauren Gilchrist, Flyer, Alec Nathanson, Sanchez, Carina Cristina, Golosov, Andrei Alexandrovich
Year of Publication 13.01.2022
Get full text
Year of Publication 13.01.2022
Patent
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
Dodd Stephanie Kay, Gaul Christoph, Karki Rajeshri Ganesh, Liansheng Su, Damon, II Robert Edson, Jain Monish, Gulgeze Efthymiou Hatice Belgin, Lin Kai, Raymer Brian Kenneth, Bebernitz Gregory Raymond, Clairmont Kevin, Kirman Louise Clare, Patel Tajesh Jayprakash, Cohen Scott Louis, Barnes David Weninger, Day Robert Francis, Mao Justin Yik Ching
Year of Publication 17.10.2017
Get full text
Year of Publication 17.10.2017
Patent
compostos de tetrâmero cíclico como inibidores de pró-proteína convertase subtilisina/kexina tipo 9 (pcsk9) para o tratamento de transtornos metabólicos
RUI ZHENG, LIANSHENG SU, ANDREI ALEXANDROVICH GOLOSOV, ALEC NATHASON FLYER, BRIAN ADDISON DECHRISTOPHER, LAUREN GILCHRIST MONOVICH, EUGENE YUEJIN LIU, CARINA CRISTINA SANCHEZ, PHILIPP GROSCHE, TAJESH JAYPRAKASH PATEL, LIHUA YANG, JUSTIN YIK CHING MAO, KARIN BRINER
Year of Publication 17.08.2021
Get full text
Year of Publication 17.08.2021
Patent
COMPUESTOS TETRÁMEROS ClCLICOS COMO INHIBIDORES DE PROPROTElNA CONVERTASA SUBTILISINA/KEXINA TIPO 9 (PCSK9) PARA EL TRATAMIENTO DE TRASTORNOS METABÓLICOS
RUI ZHENG, LIANSHENG SU, ANDREI ALEXANDROVICH GOLOSOV, BRIAN ADDISON DECHRISTOPHER, LAUREN GILCHRIST MONOVICH, EUGENE YUEJIN LIU, CARINA CRISTINA SANCHEZ, PHILIPP GROSCHE, TAJESH JAYPRAKASH PATEL, LIHUA YANG, KARIN BRINER, JUSTIN YIK CHING MAO, ALEC NATHANSON FLYER
Year of Publication 30.06.2021
Get full text
Year of Publication 30.06.2021
Patent
BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF
LIANSHENG SU, BARNES DAVID WENINGER, DAMON, II ROBERT EDSON, GULGEZE EFTHYMIOU HATICE BELGIN, PATEL TAJESH JAYPRAKASH, DODD STEPHANIE KAY, COHEN SCOTT LOUIS, CLAIRMONT KEVIN, LIN KAI, RAYMER BRIAN KENNETH, DAY ROBERT FRANCIS, KIRMAN LOUISE CLARE, GAUL CHRISTOPH, MAO JUSTIN YIK CHING, JAIN MONISH, KARKI RAJESHRI GANESH, BEBERNITZ GREGORY RAYMOND
Year of Publication 19.06.2014
Get full text
Year of Publication 19.06.2014
Patent
2-((4-((S)-2-(4-CHLORO-2-FLUOROPHENYL)-2-METHYLBENZO[D][1,3]DIOXOL-4-YL)PIPERIDIN-1-YL)METHYL)-1-(((S)-OXETAN-2-YL)METHYL)-1H-IMIDAZOLE DERIVATIVES AS ACTIVATORS OF THE GLP1 RECEPTOR FOR THE TREATMENT OF OBESITY
CARSON, Matthew, ALLAN, Martin, SMITH, Troy, ZHANG, Ping, FAZAL, Tanzina, QIAN, Ming, YANG, Lihua, CAYA, Thomas, SU, Liansheng
Year of Publication 17.08.2023
Get full text
Year of Publication 17.08.2023
Patent