Discovery of (S)‑1-(1-(Imidazo[1,2‑a]pyridin-6-yl)ethyl)-6-(1-methyl‑1H‑pyrazol-4-yl)‑1H‑[1,2,3]triazolo[4,5‑b]pyrazine (Volitinib) as a Highly Potent and Selective Mesenchymal–Epithelial Transition Factor (c-Met) Inhibitor in Clinical Development for Treatment of Cancer
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Published in Journal of medicinal chemistry (25.09.2014)
Published in Journal of medicinal chemistry (25.09.2014)
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Published in Polymers (01.09.2022)
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Preclinical pharmacokinetic characterization of amdizalisib, a novel PI3Kδ inhibitor for the treatment of hematological malignancies
Jiang, Shuwen, Li, Xiangkun, Xue, Weifang, Xia, Sumei, Wang, Jian, Sai, Yang, Dai, Guangxiu, Su, Weiguo
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Phase I study of the Syk inhibitor sovleplenib in relapsed or refractory mature B-cell tumors
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Published in Regenerative therapy (01.12.2022)
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Significantly improving mechanical properties of CF/PAI composites: the influence of interfacial modification coupled with post heat treatment
Zhou, Fang, Zhao, Zhenbo, Jing, Deqi, Zhang, Xinghua, Wang, Peng, Su, Weiguo, Zhang, Shouchun
Published in Journal of materials research and technology (01.05.2023)
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Volitinib, a potent and highly selective c-Met inhibitor, effectively blocks c-Met signaling and growth in c-MET amplified gastric cancer patient-derived tumor xenograft models
Gavine, Paul R., Ren, Yongxin, Han, Lu, Lv, Jing, Fan, Shiming, Zhang, Wei, Xu, Wen, Liu, Yuan Jie, Zhang, Tianwei, Fu, Haihua, Yu, Yongjuan, Wang, Huiying, Xu, Shirlian, Zhou, Feng, Su, Xinying, Yin, XiaoLu, Xie, Liang, Wang, Linfang, Qing, Weiguo, Jiao, Longxian, Su, Weiguo, Wang, Q. May
Published in Molecular oncology (01.01.2015)
Published in Molecular oncology (01.01.2015)
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Safety and efficacy of fruquintinib in patients with previously treated metastatic colorectal cancer: a phase Ib study and a randomized double-blind phase II study
Xu, Rui-Hua, Li, Jin, Bai, Yuxian, Xu, Jianming, Liu, Tianshu, Shen, Lin, Wang, Liwei, Pan, Hongming, Cao, Junning, Zhang, Dongsheng, Fan, Songhua, Hua, Ye, Su, Weiguo
Published in Journal of hematology and oncology (19.01.2017)
Published in Journal of hematology and oncology (19.01.2017)
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Discovery of fruquintinib, a potent and highly selective small molecule inhibitor of VEGFR 1, 2, 3 tyrosine kinases for cancer therapy
Sun, Qiaoling, Zhou, Jinghong, Zhang, Zheng, Guo, Mingchuan, Liang, Junqing, Zhou, Feng, Long, Jingwen, Zhang, Wei, Yin, Fang, Cai, Huaqing, Yang, Haibin, Zhang, Weihan, Gu, Yi, Ni, Liang, Sai, Yang, Cui, Yumin, Zhang, Meifang, Hong, Minhua, Sun, Junen, Yang, Zheng, Qing, Weiguo, Su, Weiguo, Ren, Yongxin
Published in Cancer biology & therapy (01.01.2014)
Published in Cancer biology & therapy (01.01.2014)
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Absorption, metabolism and excretion of surufatinib in rats and humans
Li, Ke, Ma, Sheng, Miao, Liyan, Fan, Songhua, Pan, Bin, Zhang, Weihan, Su, Weiguo, Xiong, Yating, Gu, Zheming, Guo, Lian, Sai, Yang
Published in Current drug metabolism (01.01.2020)
Published in Current drug metabolism (01.01.2020)
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Effects of a High-fat Meal on the Pharmacokinetics of the VEGFR Inhibitor Fruquintinib: A Randomized Phase I Study in Healthy Subjects
Qian, Hongjie, MD, Fan, Songhua, MD, Li, Ke, PhD, Sai, Yang, PhD, Su, Weiguo, PhD, Chen, Qian, PhD, Liu, Yun, MD, Li, Tingting, BS, Wang, Wei, MD, Jia, Jingying, MS, Yu, Chen, MS, Liu, Yanmei, MD
Published in Clinical therapeutics (01.08.2019)
Published in Clinical therapeutics (01.08.2019)
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Preclinical pharmacokinetics and disposition of a novel selective VEGFR inhibitor Fruquintinib (HMPL-013) and the prediction of its human pharmacokinetics
Gu, Yi, Wang, Jian, Li, Ke, Zhang, Li, Ren, Hongcan, Guo, Lixia, Sai, Yang, Zhang, Weihan, Su, Weiguo
Published in Cancer chemotherapy and pharmacology (01.07.2014)
Published in Cancer chemotherapy and pharmacology (01.07.2014)
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Circulating tumour DNA biomarkers in savolitinib-treated patients with non-small cell lung cancer harbouring MET exon 14 skipping alterations: a post hoc analysis of a pivotal phase 2 study
Yu, Yongfeng, Ren, Yongxin, Fang, Jian, Cao, Lejie, Liang, Zongan, Guo, Qisen, Han, Sen, Ji, Zimei, Wang, Ye, Sun, Yulan, Chen, Yuan, Li, Xingya, Xu, Hua, Zhou, Jianying, Jiang, Liyan, Cheng, Ying, Han, Zhigang, Shi, Jianhua, Chen, Gongyan, Ma, Rui, Fan, Yun, Sun, Sanyuan, Jiao, Longxian, Jia, Xiaoyun, Wang, Linfang, Lu, Puhan, Xu, Qian, Luo, Xian, Su, Weiguo, Lu, Shun
Published in Therapeutic advances in medical oncology (2022)
Published in Therapeutic advances in medical oncology (2022)
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Long-Term Efficacy, Safety, and Subgroup Analysis of Savolitinib in Chinese Patients With NSCLCs Harboring MET Exon 14 Skipping Alterations
Lu, Shun, Fang, Jian, Li, Xingya, Cao, Lejie, Zhou, Jianying, Guo, Qisen, Liang, Zongan, Cheng, Ying, Jiang, Liyan, Yang, Nong, Han, Zhigang, Shi, Jianhua, Chen, Yuan, Xu, Hua, Zhang, Helong, Chen, Gongyan, Ma, Rui, Sun, Sanyuan, Fan, Yun, Fan, Songhua, Yu, Jie, Lu, Puhan, Luo, Xian, Su, Weiguo
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Published in JTO clinical and research reports (01.10.2022)
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P539: A PHASE 1 STUDY OF HMPL‐306, A DUAL INHIBITOR OF MUTANT ISOCITRATE DEHYDROGENASE (IDH) 1 AND 2, IN PTS WITH RELAPSED/REFRACTORY MYELOID HEMATOLOGICAL MALIGNANCIES HARBORING IDH1 AND/OR 2 MUTATIONS
Hu, Lijuan, Zhao, Wei‐LI, Wu, Wen, Wei, Xudong, MI, Ruihua, Hu, Yu, LI, Qiubai, He, Wenjuan, LI, Juan, Dong, Yugang, Wang, Hehua, Zhang, Xuhan, Zhang, Yu, Xu, Zhongyuan, Liu, Hui, Cai, Zhen, Sun, Jie, Xu, Yajing, Jiang, Zhiping, Zhang, Cheng, Chen, Guo, Gong, Tiejun, Tang, Qinghua, Jing, Hongmei, MA, Lan, Gao, Sujun, Liu, Qiqi, Zhong, Zeyu, Ren, Yongxin, Chen, Jian, Fan, Songhua, Shi, Michael, Su, Weiguo, Huang, Xiaojun
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Inertial micro-switch capable of prolonging contact time
Deng, Kangfa, Su, Weiguo, Li, Song, Zhang, Yating, Zhang, Wei
Published in Electronics letters (29.08.2013)
Published in Electronics letters (29.08.2013)
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Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor
Cai, Yu, Yu, Jun, Ren, Ping, He, Jianlin, Wu, Zhipeng, Xiao, Kun, Jia, Hong, Wang, Jian, Sai, Yang, Dai, Guangxiu, Li, Xiong, Su, Weiguo, Ngo, Karen, Castro, Glenda, Acton, Paul D., Fung‐Leung, Wai‐Ping, Edwards, James P., Venable, Jennifer, Rao, Tadimeti S.
Published in Pharmacology research & perspectives (01.02.2020)
Published in Pharmacology research & perspectives (01.02.2020)
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Hydroxyl-functionalized block co-polyimide enables simultaneously improved toughness and strength of tetrafunctional epoxy resin
Zhang, Lili, Zhang, Xinghua, Wei, Xinghai, Jing, Deqi, Su, Weiguo, Zhang, Shouchun
Published in Composites science and technology (10.11.2022)
Published in Composites science and technology (10.11.2022)
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