Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain
Akçay, Gizem, Belmonte, Matthew A, Aquila, Brian, Chuaqui, Claudio, Hird, Alexander W, Lamb, Michelle L, Rawlins, Philip B, Su, Nancy, Tentarelli, Sharon, Grimster, Neil P, Su, Qibin
Published in Nature chemical biology (01.11.2016)
Published in Nature chemical biology (01.11.2016)
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Journal Article
GPR Image Clutter Suppression Using Gaussian Curvature Decomposition in the PCA Domain
Su, Qibin, Bi, Beizhen, Zhang, Pengyu, Shen, Liang, Huang, Xiaotao, Xin, Qin
Published in Remote sensing (Basel, Switzerland) (01.10.2022)
Published in Remote sensing (Basel, Switzerland) (01.10.2022)
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Journal Article
Abstract 979: Discovery of the JAK1 selective kinase inhibitor AZD4205
Kettle, Jason G., Su, Qibin, Grimster, Neil, Kawatkar, Sameer, Throner, Scott, Woessner, Richard, Chen, Huawei, Bebernitz, Geraldine, Bell, Kristen, Anderson, Erica, Ruston, Linette, Winter-Holt, Jon, Lyne, Paul, Vasbinder, Melissa, Chuaqui, Claudio
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Discovery of azabenzimidazole derivatives as potent, selective inhibitors of TBK1/IKKε kinases
Wang, Tao, Block, Michael A., Cowen, Scott, Davies, Audrey M., Devereaux, Erik, Gingipalli, Lakshmaiah, Johannes, Jeffrey, Larsen, Nicholas A., Su, Qibin, Tucker, Julie A., Whitston, David, Wu, Jiaquan, Zhang, Hai-Jun, Zinda, Michael, Chuaqui, Claudio
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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Journal Article
Discovery of novel hedgehog antagonists from cell-based screening: Isosteric modification of p38 bisamides as potent inhibitors of SMO
Yang, Bin, Hird, Alexander W., Russell, Daniel John, Fauber, Benjamin P., Dakin, Les A., Zheng, Xiaolan, Su, Qibin, Godin, Robert, Brassil, Patrick, Devereaux, Erik, Janetka, James W.
Published in Bioorganic & medicinal chemistry letters (15.07.2012)
Published in Bioorganic & medicinal chemistry letters (15.07.2012)
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Journal Article
Stereochemical Diversity through Cyclodimerization: Synthesis of Polyketide-like Macrodiolides
Su, Qibin, Beeler, Aaron B, Lobkovsky, Emil, Porco, John A, Panek, James S
Published in Organic letters (12.06.2003)
Published in Organic letters (12.06.2003)
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Journal Article
Enantioselective Synthesis of Linear Polypropionate Arrays Using Anthracene-Tagged Organosilanes
Kesavan, Sarathy, Su, Qibin, Shao, Jian, Porco, John A, Panek, James S
Published in Organic letters (29.09.2005)
Published in Organic letters (29.09.2005)
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Journal Article
Discovery of the Potent and Selective Inhaled Janus Kinase 1 Inhibitor AZD4604 and Its Preclinical Characterization
Nilsson, Magnus, Berggren, Kristina, Berglund, Susanne, Cerboni, Silvia, Collins, Mia, Dahl, Göran, Elmqvist, David, Grimster, Neil P., Hendrickx, Ramon, Johansson, Johan R., Kettle, Jason G., Lepistö, Matti, Rhedin, Magdalena, Smailagic, Amir, Su, Qibin, Wennberg, Tiiu, Wu, Allan, Österlund, Torben, Naessens, Thomas, Mitra, Suman
Published in Journal of medicinal chemistry (12.10.2023)
Published in Journal of medicinal chemistry (12.10.2023)
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Discovery of (2R)‑N‑[3-[2-[(3-Methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]‑1H‑indol-7-yl]-2-(4-methylpiperazin-1-yl)propenamide (AZD4205) as a Potent and Selective Janus Kinase 1 Inhibitor
Su, Qibin, Banks, Erica, Bebernitz, Geraldine, Bell, Kirsten, Borenstein, Cassandra F, Chen, Huawei, Chuaqui, Claudio E, Deng, Nanhua, Ferguson, Andrew D, Kawatkar, Sameer, Grimster, Neil P, Ruston, Linette, Lyne, Paul D, Read, Jon A, Peng, Xianyou, Pei, Xiaohui, Fawell, Stephen, Tang, Zhanlei, Throner, Scott, Vasbinder, Melissa M, Wang, Haoyu, Winter-Holt, Jon, Woessner, Richard, Wu, Allan, Yang, Wenzhan, Zinda, Michael, Kettle, Jason G
Published in Journal of medicinal chemistry (14.05.2020)
Published in Journal of medicinal chemistry (14.05.2020)
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Journal Article
Novel potent and selective pyrazolylpyrimidine-based SYK inhibitors
Barlaam, Bernard, Boiko, Scott, Boyd, Scott, Dry, Hannah, Gingipalli, Lakshmaiah, Ikeda, Timothy, Johnson, Tony, Kawatkar, Sameer, Lorthioir, Olivier, Pike, Andy, Pollard, Hannah, Read, Jon, Su, Qibin, Wang, Haiyun, Wang, Huimin, Wang, Lianghe, Wang, Peng, Edmondson, Scott D.
Published in Bioorganic & medicinal chemistry letters (15.11.2020)
Published in Bioorganic & medicinal chemistry letters (15.11.2020)
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Journal Article
Discovery of 1-Methyl-1 H -imidazole Derivatives as Potent Jak2 Inhibitors
Su, Qibin, Ioannidis, Stephanos, Chuaqui, Claudio, Almeida, Lynsie, Alimzhanov, Marat, Bebernitz, Geraldine, Bell, Kirsten, Block, Michael, Howard, Tina, Huang, Shan, Huszar, Dennis, Read, Jon A., Rivard Costa, Caroline, Shi, Jie, Su, Mei, Ye, Minwei, Zinda, Michael
Published in Journal of medicinal chemistry (09.01.2014)
Published in Journal of medicinal chemistry (09.01.2014)
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Journal Article
Inhibitors of JAK-family kinases: an update on the patent literature 2013-2015, part 1
Kettle, Jason G, Åstrand, Annika, Catley, Matthew, Grimster, Neil P, Nilsson, Magnus, Su, Qibin, Woessner, Richard
Published in Expert opinion on therapeutic patents (01.02.2017)
Published in Expert opinion on therapeutic patents (01.02.2017)
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Journal Article
Optimization of a series of novel, potent and selective Macrocyclic SYK inhibitors
Grimster, Neil P., Gingipalli, Lakshmaiah, Balazs, Amber, Barlaam, Bernard, Boiko, Scott, Boyd, Scott, Dry, Hannah, Goldberg, Frederick W., Ikeda, Tim, Johnson, Tony, Kawatkar, Sameer, Kemmitt, Paul, Lamont, Scott, Lorthioir, Olivier, Mfuh, Adelphe, Patel, Joe, Pike, Andy, Read, Jon, Romero, Romulo, Sarkar, Ujjal, Sha, Li, Simpson, Iain, Song, Kun, Su, Qibin, Wang, Haixia, Watson, David, Wu, Allan, Zehnder, Troy E., Zheng, XiaoLan, Li, Shaolu, Dong, Zhiqiang, Yang, Dejian, Song, Yanwei, Wang, Peng, Liu, Xuemei, Dowling, James E., Edmondson, Scott D.
Published in Bioorganic & medicinal chemistry letters (15.07.2023)
Published in Bioorganic & medicinal chemistry letters (15.07.2023)
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Journal Article
Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors
Yang, Bin, Vasbinder, Melissa M, Hird, Alexander W, Su, Qibin, Wang, Haixia, Yu, Yan, Toader, Dorin, Lyne, Paul D, Read, Jon A, Breed, Jason, Ioannidis, Stephanos, Deng, Chun, Grondine, Michael, DeGrace, Nancy, Whitston, David, Brassil, Patrick, Janetka, James W
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
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Journal Article
Discovery of 1‑Methyl‑1H‑imidazole Derivatives as Potent Jak2 Inhibitors
Su, Qibin, Ioannidis, Stephanos, Chuaqui, Claudio, Almeida, Lynsie, Alimzhanov, Marat, Bebernitz, Geraldine, Bell, Kirsten, Block, Michael, Howard, Tina, Huang, Shan, Huszar, Dennis, Read, Jon A, Rivard Costa, Caroline, Shi, Jie, Su, Mei, Ye, Minwei, Zinda, Michael
Published in Journal of medicinal chemistry (09.01.2014)
Published in Journal of medicinal chemistry (09.01.2014)
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Journal Article
Identification of a novel series of azabenzimidazole-derived inhibitors of spleen tyrosine kinase
Kawatkar, Sameer P., Barlaam, Bernard, Kemmitt, Paul, Simpson, Iain, Watson, David, Wang, Peng, Lamont, Scott, Su, Qibin, Boiko, Scott, Ikeda, Timothy, Patel, Joe, Pike, Andy, Pollard, Hannah, Read, Jon, Sarkar, Ujjal, Wang, Haiyun, Wen, Quanshan, Yan, Zhiyuan, Dowling, James E., Dry, Hannah, Edmondson, Scott D.
Published in Bioorganic & medicinal chemistry letters (15.09.2020)
Published in Bioorganic & medicinal chemistry letters (15.09.2020)
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Journal Article
Abstract C40: Inhibition of Mcl-1 through covalent modification of a non-catalytic lysine side chain
Su, Qibin, Akçay, Gizem, Grimster, Neil, Belmonte, Matthew, Rawlins, Philip, Lamb, Michelle, Hird, Alexander, Aquila, Brian
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Journal Article
Discovery and Optimization of a Novel Series of Highly Selective JAK1 Kinase Inhibitors
Grimster, Neil P, Anderson, Erica, Alimzhanov, Marat, Bebernitz, Geraldine, Bell, Kirsten, Chuaqui, Claudio, Deegan, Tracy, Ferguson, Andrew D, Gero, Thomas, Harsch, Andreas, Huszar, Dennis, Kawatkar, Aarti, Kettle, Jason G, Lyne, Paul, Read, Jon A, Rivard Costa, Caroline, Ruston, Linette, Schroeder, Patricia, Shi, Jie, Su, Qibin, Throner, Scott, Toader, Dorin, Vasbinder, Melissa, Woessner, Richard, Wang, Haixia, Wu, Allan, Ye, Minwei, Zheng, Weijia, Zinda, Michael
Published in Journal of medicinal chemistry (28.06.2018)
Published in Journal of medicinal chemistry (28.06.2018)
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