Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
Area-Gomez, Estela, del Carmen Lara Castillo, Maria, Tambini, Marc D, Guardia-Laguarta, Cristina, de Groof, Ad J C, Madra, Moneek, Ikenouchi, Junichi, Umeda, Masato, Bird, Thomas D, Sturley, Stephen L, Schon, Eric A
Published in The EMBO journal (05.11.2012)
Published in The EMBO journal (05.11.2012)
Get full text
Journal Article
Potential COVID-19 therapeutics from a rare disease: weaponizing lipid dysregulation to combat viral infectivity
Sturley, Stephen L., Rajakumar, Tamayanthi, Hammond, Natalie, Higaki, Katsumi, Márka, Zsuzsa, Márka, Szabolcs, Munkacsi, Andrew B.
Published in Journal of lipid research (01.07.2020)
Published in Journal of lipid research (01.07.2020)
Get full text
Journal Article
Phosphatidate Phosphatase Activity Plays Key Role in Protection against Fatty Acid-induced Toxicity in Yeast
Fakas, Stylianos, Qiu, Yixuan, Dixon, Joseph L., Han, Gil-Soo, Ruggles, Kelly V., Garbarino, Jeanne, Sturley, Stephen L., Carman, George M.
Published in The Journal of biological chemistry (19.08.2011)
Published in The Journal of biological chemistry (19.08.2011)
Get full text
Journal Article
Sterol and Diacylglycerol Acyltransferase Deficiency Triggers Fatty Acid-mediated Cell Death
Garbarino, Jeanne, Padamsee, Mahajabeen, Wilcox, Lisa, Oelkers, Peter M., D'Ambrosio, Diana, Ruggles, Kelly V., Ramsey, Nicole, Jabado, Omar, Turkish, Aaron, Sturley, Stephen L.
Published in The Journal of biological chemistry (06.11.2009)
Published in The Journal of biological chemistry (06.11.2009)
Get full text
Journal Article
Mapping the functional yeast ABC transporter interactome
Snider, Jamie, Hanif, Asad, Lee, Mid Eum, Jin, Ke, Yu, Analyn R, Graham, Chris, Chuk, Matthew, Damjanovic, Dunja, Wierzbicka, Marta, Tang, Priscilla, Balderes, Dina, Wong, Victoria, Jessulat, Matthew, Darowski, Katelyn D, San Luis, Bryan-Joseph, Shevelev, Igor, Sturley, Stephen L, Boone, Charles, Greenblatt, Jack F, Zhang, Zhaolei, Paumi, Christian M, Babu, Mohan, Park, Hay-Oak, Michaelis, Susan, Stagljar, Igor
Published in Nature chemical biology (01.09.2013)
Published in Nature chemical biology (01.09.2013)
Get full text
Journal Article
An “Exacerbate-reverse” Strategy in Yeast Identifies Histone Deacetylase Inhibition as a Correction for Cholesterol and Sphingolipid Transport Defects in Human Niemann-Pick Type C Disease
Munkacsi, Andrew B., Chen, Fannie W., Brinkman, Matthew A., Higaki, Katsumi, Gutiérrez, Giselle Domínguez, Chaudhari, Jagruti, Layer, Jacob V., Tong, Amy, Bard, Martin, Boone, Charles, Ioannou, Yiannis A., Sturley, Stephen L.
Published in The Journal of biological chemistry (08.07.2011)
Published in The Journal of biological chemistry (08.07.2011)
Get full text
Journal Article
Sterols and sphingolipids: Dynamic duo or partners in crime?
Gulati, Sonia, Liu, Ying, Munkacsi, Andrew B., Wilcox, Lisa, Sturley, Stephen L.
Published in Progress in lipid research (01.10.2010)
Published in Progress in lipid research (01.10.2010)
Get full text
Journal Article
The pathophysiology and mechanisms of NP-C disease
Sturley, Stephen L., Patterson, Marc C., Balch, William, Liscum, Laura
Published in Biochimica et biophysica acta (11.10.2004)
Published in Biochimica et biophysica acta (11.10.2004)
Get full text
Journal Article
Transcriptional Profiling Identifies Two Members of the ATP-binding Cassette Transporter Superfamily Required for Sterol Uptake in Yeast
Wilcox, Lisa J., Balderes, Dina A., Wharton, Brook, Tinkelenberg, Arthur H., Rao, Govinda, Sturley, Stephen L.
Published in The Journal of biological chemistry (06.09.2002)
Published in The Journal of biological chemistry (06.09.2002)
Get full text
Journal Article
The complexity of a monogenic neurodegenerative disease: More than two decades of therapeutic driven research into Niemann-Pick type C disease
Hammond, Natalie, Munkacsi, Andrew B., Sturley, Stephen L.
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.08.2019)
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.08.2019)
Get full text
Journal Article
Exacerbating and reversing lysosomal storage diseases: from yeast to humans
Rajakumar, Tamayanthi, Munkacsi, Andrew B, Sturley, Stephen L
Published in Microbial cell (25.08.2017)
Published in Microbial cell (25.08.2017)
Get full text
Journal Article
Loss of Subcellular Lipid Transport Due to ARV1 Deficiency Disrupts Organelle Homeostasis and Activates the Unfolded Protein Response
Shechtman, Caryn F., Henneberry, Annette L., Seimon, Tracie A., Tinkelenberg, Arthur H., Wilcox, Lisa J., Lee, Eunjee, Fazlollahi, Mina, Munkacsi, Andrew B., Bussemaker, Harmen J., Tabas, Ira, Sturley, Stephen L.
Published in The Journal of biological chemistry (08.04.2011)
Published in The Journal of biological chemistry (08.04.2011)
Get full text
Journal Article
Decreased Expression of ARV1 Results in Cholesterol Retention in the Endoplasmic Reticulum and Abnormal Bile Acid Metabolism
Tong, Fumin, Billheimer, Jeffrey, Shechtman, Caryn F., Liu, Ying, Crooke, Roseann, Graham, Mark, Cohen, David E., Sturley, Stephen L., Rader, Daniel J.
Published in The Journal of biological chemistry (29.10.2010)
Published in The Journal of biological chemistry (29.10.2010)
Get full text
Journal Article
Unraveling the sterol-trafficking defect in Niemann-Pick C disease
Sturley, Stephen L, Patterson, Marc C, Pentchev, Peter
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2009)
Get full text
Journal Article
Overexpression of Human Diacylglycerol Acyltransferase 1, Acyl-CoA:Cholesterol Acyltransferase 1, or Acyl-CoA:Cholesterol Acyltransferase 2 Stimulates Secretion of Apolipoprotein B-containing Lipoproteins in McA-RH7777 Cells
Liang, John J, Oelkers, Peter, Guo, Cuiying, Chu, Pi-Chun, Dixon, Joseph L, Ginsberg, Henry N, Sturley, Stephen L
Published in The Journal of biological chemistry (22.10.2004)
Published in The Journal of biological chemistry (22.10.2004)
Get full text
Journal Article
Mutagenesis of the Putative Sterol-Sensing Domain of Yeast Niemann Pick C-Related Protein Reveals a Primordial Role in Subcellular Sphingolipid Distribution
Malathi, Krishnamurthy, Higaki, Katsumi, Tinkelenberg, Arthur H., Balderes, Dina A., Almanzar-Paramio, Dorca, Wilcox, Lisa J., Erdeniz, Naz, Redican, Francis, Padamsee, Mahajabeen, Liu, Ying, Khan, Sohail, Alcantara, Frederick, Carstea, Eugene D., Morris, Jill A., Sturley, Stephen L.
Published in The Journal of cell biology (16.02.2004)
Published in The Journal of cell biology (16.02.2004)
Get full text
Journal Article