Efficacy and safety of intravenous belimumab in Japanese patients with systemic lupus erythematosus: A subgroup analysis of a phase 3 randomized placebo-controlled trial
Tanaka, Yoshiya, Bass, Damon, Chu, Myron, Egginton, Sally, Ji, Beulah, Struemper, Herbert, Roth, David
Published in Modern rheumatology (04.05.2019)
Published in Modern rheumatology (04.05.2019)
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Journal Article
Population pharmacokinetics of belantamab mafodotin, a BCMA‐targeting agent in patients with relapsed/refractory multiple myeloma
Rathi, Chetan, Collins, Jon, Struemper, Herbert, Opalinska, Joanna, Jewell, Roxanne C., Ferron‐Brady, Geraldine
Published in CPT: pharmacometrics and systems pharmacology (01.08.2021)
Published in CPT: pharmacometrics and systems pharmacology (01.08.2021)
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Journal Article
Reductions in circulating B cell subsets and immunoglobulin G levels with long-term belimumab treatment in patients with SLE
Struemper, Herbert, Kurtinecz, Milena, Edwards, Lisa, Freimuth, William W, Roth, David A, Stohl, William
Published in Lupus science & medicine (01.02.2022)
Published in Lupus science & medicine (01.02.2022)
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Journal Article
Longitudinal efficacy and safety modeling and simulation framework to aid dose selection of belantamab mafodotin for patients with multiple myeloma
Collins, Jon, van Noort, Martijn, Rathi, Chetan, Post, Teun M, Struemper, Herbert, Jewell, Roxanne C, Ferron-Brady, Geraldine
Published in CPT: pharmacometrics and systems pharmacology (01.10.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.10.2023)
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Manufacturing‐dependent change in biological activity of the TLR4 agonist GSK1795091 and implications for lipid A analog development
Steeghs, Neeltje, Hansen, Aaron R., Hanna, Glenn J., Garralda, Elena, Park, Haeseong, Strauss, James, Adam, Michael, Campbell, Gossett, Carver, Jennifer, Easton, Rachael, Mays, Katherine, Skrdla, Peter, Struemper, Herbert, Washburn, Michael L., Matheny, Christopher, Piha‐Paul, Sarina A.
Published in Clinical and translational science (01.11.2022)
Published in Clinical and translational science (01.11.2022)
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Journal Article
First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1)
Postel-Vinay, Sophie, Lam, Vincent K, Ros, Willeke, Bauer, Todd M, Hansen, Aaron R, Cho, Daniel C, Stephen Hodi, F, Schellens, Jan H M, Litton, Jennifer K, Aspeslagh, Sandrine, Autio, Karen A, Opdam, Frans L, McKean, Meredith, Somaiah, Neeta, Champiat, Stephane, Altan, Mehmet, Spreafico, Anna, Rahma, Osama, Paul, Elaine M, Ahlers, Christoph M, Zhou, Helen, Struemper, Herbert, Gorman, Shelby A, Watmuff, Maura, Yablonski, Kaitlin M, Yanamandra, Niranjan, Chisamore, Michael J, Schmidt, Emmett V, Hoos, Axel, Marabelle, Aurelien, Weber, Jeffrey S, Heymach, John V
Published in Journal for immunotherapy of cancer (01.03.2023)
Published in Journal for immunotherapy of cancer (01.03.2023)
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Journal Article
Chemoimmunotherapy using pegylated liposomal Doxorubicin and interleukin-18 in recurrent ovarian cancer: a phase I dose-escalation study
Simpkins, Fiona, Flores, Aurea, Chu, Christina, Berek, Jonathan S, Lucci, 3rd, Joseph, Murray, Sharon, Bauman, John, Struemper, Herbert, Germaschewski, Fiona, Jonak, Zdenka, Gardner, Olivia, Toso, John, Coukos, George
Published in Cancer immunology research (01.09.2013)
Published in Cancer immunology research (01.09.2013)
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Journal Article
Population Pharmacokinetics (PopPK) and Exposure-Response (E-R) Analyses for Belantamab Mafodotin Monotherapy in Patients with Relapsed/Refractory Multiple Myeloma (RRMM) Enrolled in DREAMM-2 and DREAMM-3
Ferron-Brady, Geraldine, Taylor, Adekemi, Kaullen, Josh, Polireddy, Kishore, McKeown, Astrid, Sule, Neal, Struemper, Herbert
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Pharmacokinetics of Belimumab in Children With Systemic Lupus Erythematosus
Dimelow, Richard, Ji, Beulah, Struemper, Herbert
Published in Clinical pharmacology in drug development (01.06.2021)
Published in Clinical pharmacology in drug development (01.06.2021)
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Journal Article
Safety and efficacy of intravenous belimumab in children with systemic lupus erythematosus: results from a randomised, placebo-controlled trial
Brunner, Hermine I, Abud-Mendoza, Carlos, Viola, Diego O, Calvo Penades, Inmaculada, Levy, Deborah, Anton, Jordi, Calderon, Julia E, Chasnyk, Vyacheslav G, Ferrandiz, Manuel A, Keltsev, Vladimir, Paz Gastanaga, Maria E, Shishov, Michael, Boteanu, Alina Lucica, Henrickson, Michael, Bass, Damon, Clark, Kenneth, Hammer, Anne, Ji, Beulah N, Nino, Antonio, Roth, David A, Struemper, Herbert, Wang, Mei-Lun, Martini, Alberto, Lovell, Daniel, Ruperto, Nicolino, Cuttica, Rubén, Silverman, Earl, Miettunen, Paivi, Kawano, Yoshifumi, Takei, Syuji, Iwata, Naomi, Mori, Masaaki, Umebayashi, Hiroaki, Smolewska, Elzbieta, Gazda, Agnieszka, Rutkowska-Sak, Lidia, Ciurtin, Coziana, Ioannou, John, Clinch, Jacqui Georgina, McCann, Liza Jennifer, Baildam, Eileen Marion, Pilkington, Clarissa, Jerath, Rita Sethi, Syed, Reema Hameed, Wahezi, Dawn M, Jung, Lawrence K L
Published in Annals of the rheumatic diseases (01.10.2020)
Published in Annals of the rheumatic diseases (01.10.2020)
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Journal Article
Exposure-Response (E-R) for Ocular Safety Endpoints for Belantamab Mafodotin (Belamaf), a B-Cell Maturation Antigen (BCMA)-Targeting Agent, in Patients with Relapsed/Refractory Multiple Myeloma (RRMM) in the DREAMM-2 Study
Ferron-Brady, Geraldine, Rathi, Chetan, Collins, Jon, Struemper, Herbert, Opalinska, Joanna, Jewell, Roxanne C
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Abstract CT196: Therapeutic dose selection for belantamab mafodotin, a BCMA-targeting agent, in patients with relapsed/refractory multiple myeloma (RRMM): Application of population pharmacokinetics (PopPK) and exposure-response (E-R) analyses
Ferron-Brady, Geraldine, Rathi, Chetan, Collins, Jon, Struemper, Herbert, Opalinska, Joanna, Jewell, Roxanne C
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Exposure–Response Analyses for Therapeutic Dose Selection of Belantamab Mafodotin in Patients With Relapsed/Refractory Multiple Myeloma
Ferron‐Brady, Geraldine, Rathi, Chetan, Collins, Jon, Struemper, Herbert, Opalinska, Joanna, Visser, Sandra, Jewell, Roxanne C.
Published in Clinical pharmacology and therapeutics (01.11.2021)
Published in Clinical pharmacology and therapeutics (01.11.2021)
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Journal Article
Safety, Pharmacokinetics, and Pharmacodynamics of the TLR4 Agonist GSK1795091 in Healthy Individuals: Results from a Randomized, Double-blind, Placebo-controlled, Ascending Dose Study
Hug, Bruce A., Matheny, Christopher J., Burns, Olivia, Struemper, Herbert, Wang, Xiaowei, Washburn, Michael L.
Published in Clinical therapeutics (01.08.2020)
Published in Clinical therapeutics (01.08.2020)
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Journal Article
P-245 Belantamab mafodotin in patients with severely impaired renal function: a phase I, 2-part study to evaluate pharmacokinetics, safety and efficacy in patients with relapsed/refractory multiple myeloma
Shafi-Harji, Seema, Nugent, Courtney, Ferron-Brady, Geraldine, Delimpasi, Sosana, Dimopoulos, Meletios, Chen, Yunxin, Chng, Wee Joo, Lee, Jae Hoon, Ailawadhi, Sikander, Gowin, Krisstina, Arning, Michael, Struemper, Herbert
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
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Journal Article
Opportunities for Quantitative Translational Modeling in Oncology
Yates, James W.T., Byrne, Helen, Chapman, Sonya C., Chen, Tao, Cucurull‐Sanchez, Lourdes, Delgado‐SanMartin, Juan, Di Veroli, Giovanni, Dovedi, Simon J., Dunlop, Carina, Jena, Rajesh, Jodrell, Duncan, Martin, Emma, Mercier, Francois, Ramos‐Montoya, Antonio, Struemper, Herbert, Vicini, Paolo
Published in Clinical pharmacology and therapeutics (01.09.2020)
Published in Clinical pharmacology and therapeutics (01.09.2020)
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Journal Article
Abstract CT150: A first-in-human phase I study of the OX40 agonist GSK3174998 (GSK998) +/- pembrolizumab in patients (Pts) with selected advanced solid tumors (ENGAGE-1)
Postel-Vinay, Sophie, Lam, Vincent K., Ros, Willeke, Bauer, Todd M., Hansen, Aaron R., Cho, Daniel C., Hodi, F. Stephen, Schellens, Jan H.M., Litton, Jennifer K., Aspeslagh, Sandrine, Autio, Karen A., Opdam, Frans L., McKean, Meredith, Somaiah, Neeta, Champiat, Stephane, Altan, Mehmet, Spreafico, Anna, Rahma, Osama, Paul, Elaine M., Ahlers, Christoph M., Zhou, Helen, Struemper, Herbert, Gorman, Shelby A., Watmuff, Maura, Yablonski, Kaitlin M., Yanamandra, Niranjan, Chisamore, Michael J., Schmidt, Emmett V., Hoos, Axel, Marabelle, Aurélien, Weber, Jeffrey S., Heymach, John V.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Evaluation of a novel autoinjector for subcutaneous self-administration of belimumab in systemic lupus erythematosus
Sheikh, Saira Z, Hammer, Anne E, Fox, Norma Lynn, Groark, James, Struemper, Herbert, Roth, David, Gordon, David
Published in International journal of clinical pharmacology and therapeutics (01.11.2016)
Published in International journal of clinical pharmacology and therapeutics (01.11.2016)
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